Fall 2007
Aug 29 (Chris): Tozuka Y, Fukuda S, Namba T, Seki T, Hisatsune T. 2005. GABAergic excitation promotes neuronal differentiation in adult hippocampal progenitor cells. Neuron 47(6):803-815.

Sept. 5 (Ji-Youn): Klassen H, Schwartz PH, Ziaeian B, Nethercott H, Young MJ, Bragadottir R, Tullis GE, Warfvinge K, Narfstrom K. 2007. Neural precursors isolated from the developing cat brain show retinal integration following transplantation to the retina of the dystrophic cat. Veterinary ophthalmology 10(4):245-253.

Sept. 12 (Jisun): Toni N, Teng EM, Bushong EA, Aimone JB, Zhao C, Consiglio A, van Praag H, Martone ME, Ellisman MH, Gage FH. 2007. Synapse formation on neurons born in the adult hippocampus. Nature neuroscience 10(6):727-734.

Sept. 19: No Club Retina/Stem Cells

Sept. 26 (Carlos): Nakanishi M, Niidome T, Matsuda S, Akaike A, Kihara T, Sugimoto H. 2007. Microglia-derived interleukin-6 and leukaemia inhibitory factor promote astrocytic differentiation of neural stem/progenitor cells. The European journal of neuroscience 25(3):649-65.

Oct. 3 (Hye-Hyun): Agarwal N, Agarwal R, Kumar DM, Ondricek A, Clark AF, Wordinger RJ, Pang IH. 2007. Comparison of expression profile of neurotrophins and their receptors in primary and transformed rat retinal ganglion cells. Molecular vision 13:1311-1318.

Oct. 10 (Ji-Youn): Pinilla I, Cuenca N, Sauve Y, Wang S, Lund RD. 2007. Preservation of outer retina and its synaptic connectivity following subretinal injections of human RPE cells in the Royal College of Surgeons rat. Experimental eye research.

Oct. 24 (Jisun): Laplagne DA, Esposito MS, Piatti VC, Morgenstern NA, Zhao C, van Praag H, Gage FH, Schinder AF. 2006. Functional convergence of neurons generated in the developing and adult hippocampus. PLoS biology 4(12):e409.

Oct. 31 (Chris): Striedinger K, Meda P, Scemes E. 2007. Exocytosis of ATP from astrocyte progenitors modulates spontaneous Ca2+ oscillations and cell migration. Glia 55(6):652-662.
Nov. 7 No Club Retina/Stem Cells - Neurosci Mtg

Nov. 14 (Carlos): Gaughwin PM, Caldwell MA, Anderson JM, Schwiening CJ, Fawcett JW, Compston DA, Chandran S. 2006. Astrocytes promote neurogenesis from oligodendrocyte precursor cells. The European journal of neuroscience 23(4):945-956.

Nov. 21 No Club Retina/Stem Cells - Thanksgiving Break

Nov. 28 (Hye-Hyun): Tomita M, Mori T, Maruyama K, Zahir T, Ward M, Umezawa A, Young MJ. 2006. A comparison of neural differentiation and retinal transplantation with bone marrow-derived cells and retinal progenitor cells. Stem cells. 24(10):2270-2278.

Dec. 5 (Chris): Ciccolini F, Collins TJ, Sudhoelter J, Lipp P, Berridge MJ, Bootman MD. 2003. Local and global spontaneous calcium events regulate neurite outgrowth and onset of GABAergic phenotype during neural precursor differentiation. J Neurosci 23(1):103-111.

Summer 2007
May 24: Chris: Yiqin Zhang, Henry J. Klassen, Budd A. Tucker, Maria-Thereza R. Perez, and Michael J. Young (2007) CNS Progenitor Cells Promote a Permissive Environment for Neurite Outgrowth via a Matrix Metalloproteinase-2-Dependent Mechanism. Jounal of Neuroscience. ;27(17):4499-506.

May 31: Jisun: Shaoyu Ge Eyleen L. K. Goh Kurt A. Sailor Yasuji Kitabatake Guo-li Ming and Hongjun Song (2006) GABA regulates synaptic integration of newly generated neurons in the adult brain. Nature 439: 589-593.
June 7: Hye0Hyun: Ayumu Tashiro, Vladislav M. Sandler, Nicolas Toni, Chunmei Zhao and Fred H. Gage (2006) NMDA-receptor-mediated, cell-specific integration of new neurons in adult dentate gyrus. Nature 442: 929-933.

June 14: Matt: Ju WK, Liu Q, Kim KY, Crowston JG, Lindsey JD, Agarwal N, Ellisman MH, Perkins GA, Weinreb RN. Elevated Hydrostatic Pressure Triggers Mitochondrial Fission and Decreases Cellular ATP in Differentiated RGC-5 Cells. Invest Ophthalmol Vis Sci. 2007 May;48(5):2145-51.

June 21: Ji-Youn: Yaniv Ziv,*† Hila Avidan,*† Stefano Pluchino,‡ Gianvito Martino,‡ and Michal Schwartz*§ (2006) Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury. Proc Natl Acad Sci U S A. 2006 August 29; 103(35): 13174–13179.

June 28: ????: Ward MS, Khoobehi A, Lavik EB, Langer R, Young MJ. 2007. Neuroprotection of retinal ganglion cells in DBA/2J mice with GDNF-loaded biodegradable microspheres. Journal of pharmaceutical sciences 96(3):558-568.

July 5: No Club Retina

July 12: ????: A. Katrin Goetz, Bjorn Scheffler, Huan-Xin Chen, Shanshan Wang, Oleg Suslov, Hui Xiang, Oliver Brüstle, Steve N. Roper, and Dennis A. Steindler (2006) Temporally restricted substrate interactions direct fate and specification of neural precursors derived from embryonic stem cells. PNAS 103:11063-11068.

July 19: ????: Evelyn K.F. Yim, Stella W. Pang and Kam W. Leong (2007) Synthetic nanostructures inducing differentiation of human mesenchymal stem cells into neuronal lineage. Experimental Cell Research 313(9), 1820-1829.

July 26: ????: Francesca Pagani, Clotilde Lauro, Sergio Fucile, Myriam Catalano, Cristina Limatola, Fabrizio Eusebi, and Francesca Grassi (2006) Functional properties of neurons derived from fetal mouse neurospheres are compatible with those of neuronal precursors in vivo. Journal of Neuroscience Research 83:1494-1501.

August 2: Carlos: D'Ascenzo, M., et al., (2006) Role of L-type Ca2+ channels in neural stem/progenitor cell differentiation. Eur J Neurosci, 2006. 23(4): p. 935-44.

Spring 2007
Jan 11: Chris: Soen Y, Mori A, Palmer TD, Brown PO. Exploring the regulation of human neural precursor cell differentiation using arrays of signaling microenvironments. Mol Syst Biol. 2006;2:37. Epub 2006 Jul 4.

Jan 18: Jisun: Lamba DA, Karl MO, Ware CB, Reh TA. Efficient generation of retinal progenitor cells from human embryonic stem cells. Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12769-74. Epub 2006 Aug 14.

Jan 25: Matt: Nakazawa T, Nakazawa C, Matsubara A, Noda K, Hisatomi T, She H, Michaud N, Hafezi-Moghadam A, Miller JW, Benowitz LI. Tumor necrosis factor-alpha mediates oligodendrocyte death and delayed retinal ganglion cell loss in a mouse model of glaucoma. J Neurosci. 2006 Dec 6;26(49):12633-41.

Feb. 8: Chris:De Coppi P, Bartsch G Jr, Siddiqui MM, Xu T, Santos CC, Perin L, Mostoslavsky G, Serre AC, Snyder EY, Yoo JJ, Furth ME, Soker S, Atala A. Isolation of amniotic stem cell lines with potential for therapy. Nat Biotechnol. 2007 Jan;25(1):100-6. Epub 2007 Jan 7.

Feb. 15: Jisun: Gao L, Miller RH. Specification of optic nerve oligodendrocyte precursors by retinal ganglion cell axons. J Neurosci. 2006 Jul 19;26(29):7619-28.

Feb. 22: Matt: Das AV, Mallya KB, Zhao X, Ahmad F, Bhattacharya S, Thoreson WB, Hegde GV, Ahmad I. Neural stem cell properties of Muller glia in the mammalian retina: regulation by Notch and Wnt signaling. Dev Biol. 2006 Nov 1;299(1):283-302. Epub 2006 Jul 29.

Mar. 22: Chris: Mumm JS, Williams PR, Godinho L, Koerber A, Pittman AJ, Roeser T, Chien CB, Baier H, Wong RO. In vivo imaging reveals dendritic targeting of laminated afferents by zebrafish retinal ganglion cells. Neuron. 2006 Nov 22;52(4):609-21.

Mar. 29: Jisun: Gelain F, Bottai D, Vescovi A, Zhang S. Designer self-assembling Peptide nanofiber scaffolds for adult mouse neural stem cell 3-dimensional cultures. PLoS ONE. 2006 Dec 27;1:e119.

Apr. 5: Matt: Jadhav AP, Cho SH, Cepko CL. Notch activity permits retinal cells to progress through multiple progenitor states and acquire a stem cell property. Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):18998-9003. Epub 2006 Dec 5.

Apr. 12: Kriss Canola, Brigitte Angénieux, Meriem Tekaya, Alexander Quiambao, Muna I. Naash, Francis L. Munier, Daniel F. Schorderet, and Yvan Arsenijevic. Retinal Stem Cells Transplanted into Models of Late Stages of Retinitis Pigmentosa Preferentially Adopt a Glial or a Retinal Ganglion Cell Fate. Invest Ophthalmol Vis Sci. 2007 48: 446-454.

Apr. 19: Suzuki T, Mandai M, Akimoto M, Yoshimura N, Takahashi M. The simultaneous treatment of MMP-2 stimulants in retinal transplantation enhances grafted cell migration into the host retina. Stem Cells. 2006 Nov;24(11):2406-11.

Apr. 26: Hegde GV, James J, Das AV, Zhao X, Bhattacharya S, Ahmad I. Characterization of early retinal progenitor microenvironment: Presence of activities selective for the differentiation of retinal ganglion cells and maintenance of progenitors. Exp Eye Res. 2007 Jan 13; [Epub ahead of print]

Summer 2006
May 24: Matt: Anderson MG ,Libby RT ,Gould DB ,Smith RS ,John SW. (2005) High-dose radiation with bone marrow transfer prevents neurodegeneration in an inherited glaucoma. Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4566-71. Epub 2005 Mar 9.

May 31: Jeff: Flanagan LA, Rebaza LM, Derzic S, Schwartz PH, Monuki ES. (2006) Regulation of human neural precursor cells by laminin and integrins. J Neurosci Res. 2006 Apr;83(5):845-56.

June 9* (Please note, this a Friday): Jennifer: Ford MC, Bertram JP, Hynes SR, Michaud M, Li Q, Young M, Segal SS, Madri JA, Lavik EB. (2006) A macroporous hydrogel for the coculture of neural progenitor and endothelial cells to form functional vascular networks in vivo. Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2512-7. Epub 2006 Feb 10.

June 14: Julie: Meyer JS, Katz ML, Maruniak JA, Kirk MD. (2006) Embryonic stem cell-derived neural progenitors incorporate into degenerating retina and enhance survival of host photoreceptors. Stem Cells. 2006 Feb;24(2):274-83. Epub 2005 Aug 25.

June 21: Eun-Ah: Banin E, Obolensky A, Idelson M, Hemo I, Reinhardtz E, Pikarsky E, Ben-Hur T, Reubinoff B. (2006) Retinal incorporation and differentiation of neural precursors derived from human embryonic stem cells. Stem Cells. 2006 Feb;24(2):246-57. Epub 2005 Aug 25.

June 28: Chris: Yin Y, Henzl MT, Lorber B, Nakazawa T, Thomas TT, Jiang F, Langer R, Benowitz LI. (2006) Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells. Nat Neurosci. 2006 Jun;9(6):843-52. Epub 2006 May 14.

July 5: Jisun: Moe MC, Varghese M, Danilov AI, Westerlund U, Ramm-Pettersen J, Brundin L, Svensson M, Berg-Johnsen J, Langmoen IA. (2005) Multipotent progenitor cells from the adult human brain: neurophysiological differentiation to mature neurons. Brain 128, 2189-2199.

Fall 2005
Sept. 1: Matt: Ikeda H, Osakada F, Watanabe K, Mizuseki K, Haraguchi T, Miyoshi H, Kamiya D, Honda Y, Sasai N, Yoshimura N, Takahashi M, Sasai Y. Generation of Rx+/Pax6+ neural retinal precursors from embryonic stem cells. Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11331-6. Epub 2005 Aug 2.

Sept. 8: Jennifer: Tabar V, Panagiotakos G, Greenberg ED, Chan BK, Sadelain M, Gutin PH, Studer L. Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain. Nat Biotechnol. 2005 May;23(5):601-6. Epub 2005 Apr 24.

Sept. 15: Jisun: Cai J, Cheng A, Luo Y, Lu C, Mattson MP, Rao MS, Furukawa K. Membrane properties of rat embryonic multipotent neural stem cells. J Neurochem. 2004 Jan;88(1):212-26.

Sept. 22: Jeff: Kim J, Wu HH, Lander AD, Lyons KM, Matzuk MM, Calof AL. GDF11 controls the timing of progenitor cell competence in developing retina. Science. 2005 Jun 24;308 (5730):1927-30.

Sept. 29: Jelena: G. Tezel, Xiangjun Yang, and Jian Cai. (2005) Proteomic Identification of Oxidatively Modified Retinal Proteins in a Chronic Pressure-Induced Rat Model of Glaucoma. IOVS. 46 (9): 3177-3187.

Oct. 13: Laura: Bradford RL, Wang C, Zack DJ, Adler R. Roles of cell-intrinsic and microenvironmental factors in photoreceptor cell differentiation. Dev Biol. 2005 Aug 22; [Epub ahead of print]

Oct. 27: Alison:Wang JC, Harris WA. The role of combinational coding by homeodomain and bHLH transcription factors in retinal cell fate specification. Dev Biol. 2005 Sep 1;285(1):101-15.

Nov. 3: Jeff: Leu ST, Jacques SA, Wingerd KL, Hikita ST, Tolhurst EC, Pring JL, Wiswell D, Kinney L, Goodman NL, Jackson DY, Clegg DO. Integrin alpha4beta1 function is required for cell survival in developing retina. Dev Biol. 2004 Dec 15;276(2):416-30.

Nov. 10: Matt: Gauthier R, Joly S, Pernet V, Lachapelle P, Di Polo A. Brain-derived neurotrophic factor gene delivery to muller glia preserves structure and function of light-damaged photoreceptors. Invest Ophthalmol Vis Sci. 2005 Sep;46(9):3383-92.

Dec. 1: Tyra: Shen J, Yang X, Dong A, Petters RM, Peng YW, Wong F, Campochiaro PA. Oxidative damage is a potential cause of cone cell
death in Retinitis Pigmentosa. Journal of Cellular Physiology 2005 Jun;203 (3):457-64.

Spring 2005
January 24: Cytogenesis in the retina: Don
Young, R.W., Cell differentiation in the retina of the mouse. Anat Rec, 1985. 212(2): p. 199-205.
La Vail, M.M., D.H. Rapaport, and P. Rakic, Cytogenesis in the monkey retina. J Comp Neurol, 1991. 309(1): p. 86-114.

January 31: Cell fate determination in the retina 1: Allison
Turner, D.L. and C.L. Cepko, A common progenitor for neurons and glia persists in rat retina late in development. Nature, 1987. 328(6126): p. 131-6.
Livesey, F.J. and C.L. Cepko, Vertebrate neural cell-fate determination: lessons from the retina. Nat Rev Neurosci, 2001. 2(2): p. 109-18.

February 7: Cell fate determination in the retina 2: Laura
Altshuler, D. and C. Cepko, A temporally regulated, diffusible activity is required for rod photoreceptor development in vitro. Development, 1992. 114(4): p. 947-957.

February 14: Topographic map formation 1: Jelena
Sperry, R.W., Chemoaffinity in the orderly growth of nerve fiber patterns and connections. Proc. Natl. Acad. Sci. USA, 1963. 50: p. 703-710.
ATTARDI DG, SPERRY RW. Preferential selection of central pathways by regenerating optic fibers. Exp Neurol. 1963 Jan;7:46-64.
SPERRY RW. The growth of nerve circuits. Sci Am. 1959 Nov;201:68-75.

February 21: Topographic map formation 2: Matt
Cox, E.C., B. Muller, and F. Bonhoeffer, Axonal guidance in the chick visual system: posterior tectal membranes induce collapse of growth cones from the temporal retina. Neuron, 1990. 4(1): p. 31-7.
Drescher, U., et al., In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases. Cell, 1995. 82(3): p. 359-70.
O'Leary DD, Wilkinson DG. Eph receptors and ephrins in neural development. Curr Opin Neurobiol. 1999 Feb;9(1):65-73.

February 28: The role of activity in retinal development: Jeff
Meister, M., et al., Synchronous bursts of action potentials in ganglion cells of the developing mammalian retina. Science, 1991. 252: p. 939-43.
Feller MB, Wellis DP, Stellwagen D, Werblin FS, Shatz CJ. Requirement for cholinergic synaptic transmission in the propagation of spontaneous retinal waves. Science. 1996 May 24;272(5265):1182-7.
Wong RO. Patterns of correlated spontaneous bursting activity in the developing mammalian retina. Semin Cell Dev Biol. 1997 Feb;8(1):5-12.

March 7: Activity and the development of the retinocollicular projection: Tyra
Shatz, Carla J. Emergence of order in visual system development. PNAS USA,1996.93:p:602-608.
Sretavan, David W. and Shatz, Carla J. Prenatal Development of Retinal Ganglion Cell Axons: Segregation into Eye-Specific Layers Within the Cat's Lateral Geniculate Nucleus. J. of Neuroscience,1986.6(1):p:234-251.

March 14: No Club Retina: Spring break

March 21: Jordan presents: Zhao X, Das AV, Soto-Leon F, Ahmad I. Growth factor-responsive progenitors in the postnatal mammalian retina.Dev Dyn. 2005 Feb;232(2):349-58.

March 28: Matt

April 4: Jennifer: E.B. Lavik, Klassen, H. Warfvinge, K., Langer,R. and Young M.J. Fabrication of degradable polymer scaffolds to direct integration and differentiation of retinal progenitors. Biomaterials 26 (2005) 3187-3196.

April 11: Jelena: Cheng-Wu Zhang, Qiang Lu, Si-Wei You, Ye Zhi, Henry K. Yip, Wutian Wu, Kwok-Fai So, and Qi Cui. CNTF and BDNF Have Similar Effects on Retinal Ganglion Cell Survival but Differential Effects on Nitric Oxide Synthase Expression Soon after Optic Nerve Injury (2005) Investigative Ophthalmology and Visual Science. 46: 1497-1503.

April 18: Allison: Zahir T, Klassen H, Young MJ. Effects of ciliary neurotrophic factor on differentiation of late retinal progenitor cells. Stem Cells. 2005 Mar;23(3):424-32.

April 25: Jeff: Qiu G, Seiler MJ, Mui C, Arai S, Aramant RB, Juan E Jr, Sadda S. (2005) Photoreceptor differentiation and integration of retinal progenitor cells transplanted into transgenic rats. Exp Eye Res. 2005 Apr;80(4):515-25.

Fall 2004
Aug. 30: Jennifer Recknor presents: Shen Q, Goderie SK, Jin L, Karanth N, Sun Y, Abramova N, Vincent P, Pumiglia K, Temple S. "Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells." Science. 2004 May 28;304(5675):1338-40. Epub 2004 Apr 01. Additional Supplemental materials

Sept. 13: Matt Harper presents: David A. Feldheim, Masaru Nakamoto, Miriam Osterfield, Nicholas W. Gale, Thomas M. DeChiara, Rajat Rhoatgi, George D. Yancopoulos, and John G. Flanagan. (2004) Loss-of-Function Analysis of EphA Receptors in Retinotectal Mapping. The Journal of Neuroscience, March 10 2004 24(10): 2542-2550

Sept. 27: Jeff Orasky presents: Tabata Y, Ouchi Y, Kamiya H, Manabe T, Arai K, Watanabe S. Specification of the retinal fate of mouse embryonic stem cells by ectopic expression of Rx/rax, a homeobox gene. Mol Cell Biol. 2004 May;24(10):4513-21.

Oct. 4: Jelena Ostojic presents: Fran Shen, Bin Chen, John Danias, Kevin C. Lee, Hokyung Lee, Yanling Su, Steven M. Podos, and Thom W. Mittag (2004) Glutamate-Induced Glutamine Synthetase Expression in Retinal Müller Cells after Short-term Ocular Hypertension in the Rat. Invest. Ophthalmol. Vis. Sci. 2004 45:3107-3112.

Oct. 11: Jordon Rixon presents: Otani A, Dorrell MI, Kinder K, Moreno SK, Nusinowitz S, Banin E, Heckenlively J, Friedlander M. Rescue of retinal degeneration by intravitreally injected adult bone marrow-derived lineage-negative hematopoietic stem cells. Journal of Clinical Investigation. 2004 Sep; 114(6):765-74.

Nov. 8: Tyra Dunn presents: Kaori Amemiya, Masatoshi Haruta, Masayo Takahashi, Mitsuko Kosaka, and Goro Eguchi (2004) Adult human retinal pigment epithelial cells capable of differentiating into neuron. Biochemical and Biophysical Research Communications 316 (2004) 1­5

Nov. 15: Dan Zamzow presents: Hao Chena, Arthur J. Weber (2004) Brain-derived neurotrophic factor reduces TrkB protein and mRNA in the normal retina and following optic nerve crush in adult rats. Brain Research 1011 (2004) 99­ 106.

Nov. 22: University Holiday: No Club Retina

Nov. 29: Matt Harper presents: Brenda L. K. Coles, Brigitte Angenieux, Tomoyuki Inoue, Katia Del Rio-Tsonis, Jason R. Spence, Roderick R. McInnes, Yvan Arsenijevic, and Derek van der Kooy (2004) Facile isolation and the characterization of human retinal stem cells. PNAS. 101, #44: 15772-15777

May 31: Memorial Day: No Club Retina

June 7: Heather Greenlee presents: T.B.A. Please note, today's Club Retina will start at 4:10 PM (instead of 4:00 PM).

June 14: Jelena Ostojic presents: B. Fortune, B.V. Bui, J.C. Morrison, E.C. Johnson, J. Dong, W.O. Cepurna, L.J. Jia, S. Barber, and G.A. Cioffi. (2004) Selective Ganglion Cell Functional Loss in Rats with Experimental Glaucoma. Investigative Ophthalmology & Visual Science, June 2004, Vol. 45, No. 6: 1854-1862.

June 21: Jennifer Recknor presents: Pearse DD, Pereira FC, Marcillo AE, Bates ML, Berrocal YA, Filbin MT, Bunge MB, (2004) cAMP and Schwann cells promote axonal growth and functional recovery after spinal cord injury. Nat Med. 2004 Jun;10(6):610-6. Epub 2004 May 23.

June 28: Jordan Rixon presents: Jeffrey L. Goldberg, Mauricio E. Vargas, Jack T. Wang, Wim Mandemakers, Stephen F. Oster, David W. Stretavan, Ben A. Barres. An Oligodendrocyte Lineage-Specific Semaphorin, Sema5A, Inhibits Axon Growth by Retinal Ganglion Cells. J. Neurosci. 2004 24: 4989-4999.

July 5: University Holiday: No Club Retina

July 12:Alison Barhill presents: Rowan S, Cepko CL. (2004) Genetic analysis of the homeodomain transcription factor Chx10 in the retina using a novel multifunctional BAC transgenic mouse reporter. Dev Biol. 2004 Jul 15;271(2):388-402.

July 19: Jeff Orasky presents: Meyer JS, Katz ML, Maruniak JA, Kirk MD. (2004) Neural differentiation of mouse embryonic stem cells in vitro and after transplantation into eyes of mutant mice with rapid retinal degeneration. Brain Res. 2004 Jul 16;1014(1-2):131-44.

July 26: Laura Marsh presents: Ozawa Y, Nakao K, Shimazaki T, Takeda J, Akira S, Ishihara K, Hirano T, Oguchi Y, Okano H. (2004) Downregulation of STAT3 activation is required for presumptive rod photoreceptor cells to differentiate in the postnatal retina. Mol Cell Neurosci. 2004 Jun;26(2):258-70.

August 2: Jeff Orasky presents: Haruta M, Sasai Y, Kawasaki H, Amemiya K, Ooto S, Kitada M, Suemori H, Nakatsuji N, Ide C, Honda Y, Takahashi M. (2004) In vitro and in vivo characterization of pigment epithelial cells differentiated from primate embryonic stem cells. Invest Ophthalmol Vis Sci. 2004 Mar;45(3):1020-5.

August 9: Matt Harper presents: Wernig M, Benninger F, Schmandt T, Rade M, Tucker KL, Bussow H, Beck H, Brustle O. (2004) Functional integration of embryonic stem cell-derived neurons in vivo. J Neurosci. 2004 Jun 2;24(22):5258-68.

Feb. 2: Jelena Ostojic presents: Balwantray C. Chauhan, Terry L. LeVatte, Christine A. Jollimore, Paula K. Yu, Herbert A. Reitsamer, Melanie E. M. Kelly, Dao-Yi Yu, François Tremblay, and Michele L. Archibald. Model of Endothelin-1 Induced Chronic Optic Neuropathy in Rat. Invest Ophtalmol Vis Sci. 2004 Jan; 45(1): 144-152.

Feb. 9: Jeff Orasky presents: Jin Z, Zhang J, Klar A, Chedotal A, Rao Y, Cepko CL, Bao ZZ (2003) Irx4-mediated regulation of Slit1 expression contributes to the definition of early axonal paths inside the retina. Development. 2003 Mar;130(6):1037-48.

Feb. 16: Chase Newton presents: C. Haradaa, T. Harada, H.-M. A. Quaha, F. Maekawaa, K. Yoshidad, S. Ohnod, K. Wadac, L. F. Paradab and K. Tanaka (2003) Potential role of glial cell line-derived neurotrophic factor receptors in Müller glial cells during light-induced retinal degeneration. Neuroscience. 122, Issue 1 , 20 November 2003, Pages 229-235.

Feb. 23: Jennifer Behr presents: Shulamit Levenberg, Ngan F. Huang, Erin Lavik, Arlin B. Rogers, Joseph Itskovitz-Eldor, and Robert Langer, Differentiation of human embryonic stem cells on three-dimensional polymer scaffolds. Proceedings of the National Academy of Sciences, 2003. 100(22): p. 12741-12746.

Mar. 1: Jordan Rixon presents: Dietmar Fischer, Zhigang He, and Larry I. Benowitz (2004) Counteracting the Nogo Receptor Enhances Optic Nerve Regeneration If Retinal Ganglion Cells Are in an Active Growth State. J. Neurosci. 2004 24: 1646-1651.

Mar. 8: Alison Barnhill presents: Takahiko Matsuda and Constance L. Cepko. (2004) Electroporation and RNA interference in the rodent retina in vivo and in vitro
PNAS. 101 (1).

Mar. 15: Spring break - No Club Retina

Mar. 22: Chase Newton presents: Moshiri A, Reh TA. (2004) Persistent progenitors at the retinal margin of ptc+/- mice. J Neurosci. Jan 7;24(1):229-37.

Mar. 29: Laura Marsh presents: Zhang J, Gray J, Wu L, Leone G, Rowan S, Cepko CL, Zhu X, Craft CM, Dyer MA. Rb regulates proliferation and rod photoreceptor development in the mouse retina. Nature Genet. 2004 Feb 29 [Epub ahead of print]

April 5: Jelena Ostojic presents: Paul Aoun, James W. Simpkins, and Neeraj Agarwal. Role of PPAR- Ligands In Neuroprotection against Glutamate-Induced Cytotoxicity in Retinal Ganglion Cells. Invest. Ophthalmol. Vis. Sci. 2003 44: 2999-3004.

April 12: Jordan Rixon presents: Tomita M, Yamada H, Adachi Y, Cui Y, Yamada E, Higuchi A, Minamino K, Suzuki Y, Matsumura M, Ilkehara S. Choroidal neovascularization is provided by bone marrow cells. Stem Cells. 2004;22(1):21-6

April 19: Matt Harper presents: Rudzinski M, Wong TP, Saragovi HU. Changes in retinal expression of neurotrophins and neurotrophin receptors induced by ocular hypertension.
J Neurobiol. 2004 Feb 15;58(3):341-54.

April 26: ARVO Meeting - No Club Retina

Sept. 15: Heather Greenlee presents: Jackson James,1 Ani V. Das,1 Sumitra Bhattacharya,1 David M. Chacko,2 Xing Zhao,1 and Iqbal (2003) In Vitro Generation of Early-Born Neurons from Late Retinal Progenitors The Journal of Neuroscience, September 10, 2003 · 23(23):8193­ 8203

Sept. 22: Samantha Van Hoffelen presents: Cindi M. Morshead,1 A. Denize Garcia,2 Michael V. Sofroniew2 and Derek van der Kooy (2003) The ablation of glial fibrillary acidic protein-positive cells from the adult central nervous system results in the loss of forebrain neural stem cells but not retinal stem cells. European Journal of Neuroscience, Vol. 18, pp. 76­84.

Sept 29: Matt Harper presents: Dino Petrin, Adam Baker, Stuart G. Coupland, Peter Liston, Monica Narang, Karim Damji, Brian Leonard, Vince A. Chiodo, Adrian Timmers, William Hauswirth, Robert G. Korneluk, and Catherine Tsilfidis (2003) Structural and Functional Protection of Photoreceptors from MNU-Induced Retinal Degeneration by the X-Linked Inhibitor of Apoptosis. Invest. Ophthalmol. Vis. Sci. 2003 44: 2757-2763.

Oct. 6: Jeff Orasky presents: Keegan DJ, Kenna P, Humphries MM, Humphries P, Flitcroft DI, Coffey PJ, Lund RD, Lawrence JM. Department of Pathology, Institute of Ophthalmology, London, United Kingdom. Transplantation of syngeneic Schwann cells to the retina of the rhodopsin knockout (rho(-/-)) mouse. Invest Ophthalmol Vis Sci. 2003 Aug;44(8):3526-32

Oct. 13: Chase Newton presents: Takuya Suzuki,a Sotaro Ooto,a Tadamichi Akagi, Kaori Amemiya, Rie Igarashi, Yutaka Mizushima, and Masayo Takahashi (2003) Effects of prolonged delivery of brain-derived neurotrophic factor on the fate of neural stem cells transplanted into the developing rat retina. Biochemical and Biophysical Research Communications 309 (2003) 843­847

Oct. 20: Jordan Rixen presents: Li Y, Irwin N, Yin Y, Lanser M, Benowitz LI (2003) Axon regeneration in goldfish and rat retinal ganlion cells: differential responsiveness to carbohydrates and cAMP. Journal of Neuroscience, August 27, 2003 · 23(21):7830 ­7838.

Oct. 27: Jennifer Recknor: Eric V. Wong, Samuel David, Michele H. Jacob, and Daniel G. Jay (2003) Inactivation of Myelin-Associated Glycoprotein Enhances Optic Nerve Regeneration. The Journal of Neuroscience, April 15, 2003, 23(8):3112. See also Erratum.

Nov. 3: Chase Newton presents: Keith R. G. Martin,1 Harry A. Quigley,1 Donald J. Zack,1 Hana Levkovitch-Verbin,1 Jennifer Kielczewski,1 Danielle Valenta,1 Lisa Baumrind,1 Mary Ellen Pease,2 Ronald L. Klein,2 and William W. HauswirthGene Therapy with Brain-Derived Neurotrophic Factor As a Protection: Retinal Ganglion Cells in a Rat Glaucoma Model. Investigative Ophthalmology & Visual Science, October 2003, Vol. 44, No. 10: 4357-4365.

Nov. 10: No meeting due to Society for Neuroscience Meeting

Nov. 17: Jelena Ostojic presents: Ambati, Anand, Fernandez, Sakurai, Lynn, Kuziel, Rollins and Ambati (2003) An animal model of age-related macular degeneration in senescent Ccl-2-or Ccr-2-deficient mice. Nature Medicine. 9(11) 1390-1397.

Nov. 24: No meeting - Thanksgiving break

Dec.1: Jordan Rixen presents: Bourges JL, Gautier SE, Delie F, Bejjani RA, Jeanny JC, Gurny R, BenEzra D, Behar-Cohen FF. Ocular drug delivery targeting the retina and retinal pigment epithelium using polylactide nanoparticles. Invest Opthalmol Vis Sci. 2003 Aug; 44(8):35652-9

Dec 8: Samantha Van Hoffelen: Mariko Hirano, Akitsugu Yamamoto, Naoko Yoshimura, Tomoyuki Tokunaga, Tsutomu Motohashi, Katsuhiko Ishizaki, Hisahiro Yoshida, Kenji Okazaki, Hidetoshi Yamazaki, Shin-Ichi Hayashi, and Takahiro Kunisada (2003) Generation of Structures Formed by Lens and Retinal Cells Differentiating From Embryonic Stem Cells DEVELOPMENTAL DYNAMICS 228:664­671, 2003.