Development
and Plasticity of the
Vertebrate Retina and Visual Pathway
Coordinator:
Carlos B. Duarte, Ph.D.
CENTER FOR NEUROSCIENCE OF COIMBRA
DEPARTMENT OF ZOOLOGY
UNIVERSITY OF COIMBRA
3004-517 COIMBRA
PORTUGAL
Instructors:
| Donald Sakaguchi, Ph.D. Assoc. Prof. Dept. Zoology and Genetics Chair, Neuroscience Program Dept. Zoology and Genetics Iowa State University 339 Science II Ames, IA 50011 dssakagu@iastate.edu |
Michael Young, Ph.D. Assistant Professor Schepens Eye Research Institute, Dept. of Ophthalmology Harvard Medical School 20 Staniford Street Boston, MA 02114 mikey@vision.eri.harvard.edu |
Topics on development:
1) Neurogenesis and synaptogenesis
in the vertebrate retina
2) Formation of retinotectal connections
3) Activity and the development of the retinal projection
Topics on plasticity:
1) Neural transplants to repair the
damaged CNS
2) Therapeutic strategies for retinal restoration
3) Stem cells: what are they and what can they do
| Day/Time | Topics |
| MONDAY | APRIL 16, 2001 |
| 9:00-10:15 AM | Lecture: D. Sakaguchi Retinal development: Neurogenesis and differentiation 1 |
| 10:15-10:30 | Break |
| 10:30-11:45 | Lecture: D. Sakaguchi Retinal development: Neurogenesis and differentiation 2 |
| 11:45-1:00 PM | Break |
| 1:00-5:00 PM | Laboratory/Practical:
D. Sakaguchi; Neuronal Tract-Tracing 1 Lecture and Lab: Neuronal Tract-Tracing 1 |
| TUESDAY | APRIL 17, 2001 |
| 9:00-10:15 AM | Lecture: D. Sakaguchi Formation of retinotectal connections |
| 10:15-10:30 | Break |
| 10:30-11:45 | Lecture: D. Sakaguchi Activity and the development of the retinal projection |
| 11:45-1:00 PM | Break |
| 1:00-5:00 PM | Laboratory/Practical:
D. Sakaguchi; Neuronal Tract-Tracing 2 |
| WED. | APRIL 18, 2001 |
| 9:00-10:15 AM | Lecture: M. Young |
| 10:15-10:30 | Break |
| 10:30-11:45 | Lecture: Bioethics |
| 11:45-1:00 PM | Break |
| 1:00-3:30 PM | Laboratory/Practical: D. Sakaguchi; Neuronal Tract-Tracing 3 |
| 4:15 | Seminar: Don
Sakaguchi: "Differential expression
of SNARE complex proteins SNAP-25, Syntaxin and VAMP during development
of the mammalian retina" Room: "Serviço de Química Fisiológica", Faculty of Medicine, ground floor, Lecture room. |
| THURSDAY | APRIL 19, 2001 |
| 9:00-10:15 AM | Lecture: M. Young |
| 10:15-10:30 | Break |
| 10:30-11:45 | Lecture: M. Young |
| 11:45-1:00 PM | Break |
| 1:00-3:00 PM | Laboratory/Practical:
M. Young Isolation and culturing of neural stem cells 1 |
| 3:00-5:00 PM | Journal club discussion
session: Student presentations of current topic in neural development
and plasticity. For list of references. Room: "Serviço de Higiene", Faculty of Medicine, 2nd floor, Rm. 16 |
| FRIDAY | APRIL 20, 2001 |
| 9:00-10:15 AM | Lecture: M. Young |
| 10:15-10:30 | Break |
| 10:30-11:45 | Lecture: M. Young |
| 11:45-1:00 PM | Break |
| 1:00-3:30 PM | Laboratory/Practical:
M. Young Isolation and culturing of neural stem cells 2 |
| 4:15 | Seminar: Michael
Young: "CNS stem cell transplants
in rodent models of retinal degeneration" Room: IBILI, Lecture room. |