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Education
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Ph.D, in Biochemistry, bioinformatics
and biological statistics fields,
Iowa State University, May 2008. Advisor:
Robert Jernigan, |
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M.S. in Pharmacology,
Shanghai Institute of Materia Medica, Chinese Academy of Sciences,
July 2001 |
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B.S. in Biology,
NanKai University, Tianjin, China, June 1998 |
Skills
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Experience in bioinformatics tools:
PDB, BLAST, VMD, CHARMM, CABS etc. |
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Experience in statistical software:
SAS, R and Sigmaplot |
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Experience in database query
language: SQL, JDBC, XML |
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Experience in programming using C++,
perl and Matlab |
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Familiarity with Linux/Unix,
Microsoft windows |
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Familiarity with wet lab technologies
in molecular biology, biochemistry and pharmacology |
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Fluency in both Chinese and English |
Research Experience
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Research Assistant in the
department of Biochemistry, Biophysics, and Molecular Biology, Iowa
State University, 2002-Present
-- Development of new statistical potentials for protein structure
prediction
--Studied residue packing of proteins using probability and statistics
methods
--Combination of elastic network model and MC algorithm for studying
protein conformational change |
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Research Assistant in
Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy
of Sciences, 1998-2001
-- Studied the structure and function of opioid receptors and the
binding of analgesia (pain relieve) drugs
-- Experience in these biological technologies: molecular cloning, cell
culture and protein expression, protein separation and purification,
drug and receptor binding |
Work Experience
Publications (other 3 in preparation)
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Feng YP, Kloczkowski K,
Jernigan RL. Orientational distributions of contact clusters in proteins
closely resemble those of an icosahedron.(Accepted,
Proteins:
Structure, Function, and Bioinformatics)
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Feng YP, Kloczkowski K,
Jernigan RL. Four-body contact potentials derived from two protein
datasets to discriminate native structures from decoys.
Proteins:
Structure, Function, and Bioinformatics 68: 57 – 66, 2007 |
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Taner, S.T., Feng, Y, Garcia,
J.V., Kloczkowski, A., Jernigan, R.L. The extent of cooperativity of
protein motions observed with elastic network models is similar for
atomic and coarser-grained models. Journal of Chemical theory and
computation. J. Chem. Theory Comput., 2 (3), 696 -704, 2006. |
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Feng YP, Chen LW, Zhou DH,
Chen J, Xu XJ, Chi ZQ. Analysis of binding domain and function of
chimeric mu/kappa opioid receptors to ohmefentanyl stereoisomers. Acta
Pharmacol Sin. Nov;22(11):981-5, 2001 |
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Chen LW, Feng YP, Zhou DH , Xu
XJ, Chen J, Wei Q, and Chi ZQ. One-Step Affinity Purification of Human
Mu-Opioid Receptor Overexpressed in Baculovirus System. Protein and
Peptide Letters, 8(4):265-272, 2001
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Wan XH, Huang XQ, Zhou DH, Jiang HL,
Feng YP, Chen KX, and Chi ZQ Molecular Modeling of Kappa Opioid
Receptor-Gi Protein Recognition. Protein and Peptide Letters,
7(6):403-409, 2000 |
Presentation
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New statistical potentials for
improved threading. The Biophysical Society 51st Annual
Meeting, March 2007, Baltimore, Maryland |
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Four-body contact potentials derived
from two datasets to determine native structures from decoys. The 5th
Annual Joint Bioinformatics Workshop between UI and ISU, July 2005,
Iowa City, IA, USA. |
Teaching Experience
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Teaching Assistant, Survey of
Biochemistry (BBMB301), Fall 2005 |
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Teaching Assistant, Biochemistry
(BBMB405), Spring 2005
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Main Honors
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Research Excellence Award, Iowa State
University, 2007 |
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Premium for Academic Excellence
(PACE) Award, Iowa State University, 2002
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References
Dr. Robert L.
Jernigan
Director of L. H. Baker center for bioinformatics and biological
statistics
Professor of department of biochemistry, biophysics and molecular biology
112 Office and Lab Building
Iowa State University
Ames, IA 50011
Phone: 515-294-3833
Email:
Jernigan@iastate.edu
Fax: 515-294-3841
Dr. Andrzej Kloczkowski
Senior scientist of plant sciences institute
Adjunct professor of department of biochemistry, biophysics and molecular
biology
108 Office and Lab building
Iowa State University
Ames, IA 50011
Phone: 515-294-7261
Dr. Zhijun Wu
Associate professor of department of mathematics
Program on bioinformatics and computational biology
307 Carver Hall
Iowa State University
Ames, IA 50011
Phone: 515-294-8165
Email:
zhijun@iastate.edu
Fax: 515-294-5454
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