• Lecture: MWF 8-8:50am, Physics 3 (from Friday 1/18 on)
• Instructor: Dr. Philip Dixon, pdixon@iastate.edu, 1436 Wilson, 3405 Agronomy, 4-2142, 4-6828
• Office Hours: 3-4 M, 2-4 Weds both in 3405 Agron.
• Grader: Antonio Villaneuva-Morales, antoniov@iastate.edu Office hours: W 2-3, 0113 Pearson
• Questions?: Please feel free to e-mail me (pdixon@iastate.edu) or Antonio anytime with questions or comments.
  I often check e-mail in the evening, especially the night before homework is due.
• Class Web site: http://www.public.iastate.edu/~pdixon/stat402
  Copies of the syllabus, homework assignments, SAS code and data sets will be available here.
• Text
  SAS for Linear Models, 4th edition, ( Littell, Stroup, and Freund).
  The fourth edition is important. The 3rd lacks an important chapter.
  This will be supplemented by readings from various sources.
• Reserve materials (all 2 hour in Parks Library):
  • Ramsey, F.L. and Schafer, D.W. The Statistical Sleuth
    This was the text for Stat 401, sections A,B. If you have it, it provides an alternative treatment for simple ANOVA.
  • Kuehl, R.O. (2000) Design of Experiments: Statistical Principles of Research Design and Analysis
    I have used this as a text before. Good source of details.
  • Various texts and reference books on experimental design.
• Goals:
  • Understand the principles of experimental design.
  • Be familiar with some standard experimental designs and how to analyze data from those designs.
  • Be able to apply statistical design principles to novel problems.
• Prerequisites:
  The official prerequisite is Stat 401. I will assume that you are comfortable with t-tests, 1-way ANOVA including contrasts, and assumptions, i.e. the concepts covered in Chapters 1 - 3, 5, and 6 of Ramsey and Schaefer, The Statistical Sleuth. I do not expect you to be able to do calculations by hand or remember the formulae (we'll use the computer for all that). I realize that some of you took 401 (or its equivalent) a while ago, so this material may be rusty. There is also considerable variation between sections of 401. Please ask questions if I am assuming something you haven't seen or don't remember. Office hours are a great place to review background material.
• Grading:
  Homework: 100 pts
  Two Midterms: 100 pts each
  Final: 100 pts
• Computing:
  This course will emphasize the use of SAS for statistical computing. We will heavily use proc glm and proc mixed. I will not emphasize traditional formulae for Sums-of-Squares and other quantities. Instead, I will focus on the principles of experimental design and analysis, the use of SAS to compute the needed quantities, and the appropriate interpretation of output. Data files and example SAS programs will be distributed via the class web pages.

  For those wishing to use R, JMP, or SPSS, I will be happy to help during office hours. I will distribute R code for as many analyses as I can, but class discussion will be limited or non-existent.

  It would be best if you had access to the SAS package on a relatively powerful computer. At ISU, SAS is available on many PC's, some MAC's, and on a campus-wide server (sas.iastate.edu).

  If you want your own copy, the Statistics Dept. computing group has a multi-user student license. This is free for students on their personal machine. You will need to bring your laptop (or PC) to Wilson to have the software installed. E-mail Kathy Shelley to schedule an appointment. Installing SAS on an ISU-owned PC requires a license, which costs ca $100 per year from Statistics. Again, contact Kathy Shelley to get license information. This is a web-based installation, so you do not need to move the machine. Licenses are also available from the Agronomy Dept. These are cheaper if you're associated with Agron.

  Finally, if you want to use SAS at home or in your office, but do not want to install a copy, you can use a terminal emulator (e.g. PUTTY) to connect to sas.iastate.edu and use SAS in batch mode (dial-up internet connection) or full screen mode (fast internet connection). See the Stat Dept SAS resource page for more info.

Week   Dates        Topic 

  1   Jan 14-18      Intro / How Many Replicates? (sample size and power)
      Jan 21        ML King Birthday - no class 
  2   Jan 23-25     How many Replicates, continued
  3   Jan 28-Feb 1  Should I subsample? (variance components)
  4   Feb  4- 8     Subsampling, continued
  5   Feb 11-15     How can I reduce unwanted variability? (blocking)
  6   Feb 18-22     more blocking (Latin Squares and incomplete blocks)
      Feb 25        Midterm I due (takehome, thru end of week 5)
                       may be delayed if lecture schedule gets behind
  7   Feb 25-29     What does "interaction" mean? (factorial trt design)
  8   Mar  3- 7     Factorial designs continued.
  9   Mar 10-14     What's the right error? (split plot designs)
      Mar 17-21     Spring Break
 10   Mar 24-28       split plots, continued
 11   Mar 31-Apr 4    other designs with multiple error terms
 12   Apr  7-11     Any problem with repeatedly measuring the same plots?
      Apr 14        Midterm II due (takehome, thru end of week 11)
 13   Apr 14-18     How do I analyze data from multiple sites and years?
 14   Apr 21-25     Should I worry about spatial correlation?
 15   Apr 28-May 2  Should I measure a baseline value? (ANCOVA)
      May  5-May 9  Finals week (final will probably be takehome)

Readings: Assigned readings will be posted regularly. My lectures will cover the same concepts, but I will use different examples and a different presentation. It will help if you read the assigned material before the appropriate lectures.

Supplemental readings, from other books, will be handed out as appropriate. These are optional. They will cover the same topics as the assigned readings and are given for your information, in case you prefer another book's style.

Homework: Statistics is best learnt by doing. The homework problems give you the chance to do. Problems are written to give you practice analyzing data or to illustrate points made in lecture. The intent is to help you understand and apply lecture concepts. Discussion with friends and classmates is encouraged. Copying papers does not contribute to learning and will not be tolerated.

Homework will be assigned weekly, except when there is a midterm, and due at the start of Friday's lecture. No late homework will be accepted. The lowest homework score will be dropped.

Exams: The two midterms will be takehome exams. They will be handed out at the Wednesday lecture and are to be returned at the following Monday's lecture. If my lectures are slower than scheduled, the midterm may be delayed. The format of the final will be discussed in class. I prefer to give a takehome exam, but as a class, we may decide on a traditional 2 hour in class exam.

All exams are open book. You may use your textbook, your lecture notes, or other material from the library reserve desk. You may not use your friends or classmates. Please e-mail me if you have questions. This includes questions about SAS coding. Ask me, not a classmate.

• Midterm I is tentatively scheduled for Weds, Feb 20, - Mon, Feb 25 , covering material through end of week 5 (blocking), but probably not incomplete blocks or Latin Squares.
• Midterm II is tentatively scheduled for Weds, Apr 9, - Mon, Apr 14 , covering material through end of week 11 (probably designs with multiple errors).
• Final: Date and time depend on format and the registrar's schedule

Academic Honesty Policy:
The ISU academic honesty policy is printed in the University catalog and available online. To clarify how this applies to your work in this class:

• On homework assignments: I encourage you to help each other interpret the homework problems, write SAS code, debug SAS code, and interpret the output. You may share SAS code, but I encourage you to understand that code even if you didn't write it. I do require you to write your answers in your own words.
• On midterm and final exams: You are to do all work individually. I am very willing to answer questions and help with SAS programming. But, you are to ask me and only me for help.
• Academic life depends on trust. Violations of this policy are taken seriously.

Disability accomodation:
Iowa State University complies with the Americans with Disabilities Act and Sect 504 of the Rehabilitation Act. If you have a disability and anticipate needing accommodations in this course, please contact Philip Dixon within the first two weeks of the semester. Retroactive requests for accommodations will not be honored. Before meeting with me, you need to obtain a SAAR form with recommendations for accommodations from the Disability Resources Office, Room 1076, Student Services Building. Their telephone number is 515-294-6624.