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People
Dr. Nicole Valenzuela
I am an evolutionary biologist, and my research involves studies of:
- Evolutionary and Ecological Genomics
- Evolutionary Developmental Biology
- Sex Determination
- Population and Ecological Genetics
- Life History Evolution
- Herpetology
- Tropical Biology
- Conservation
Publications
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Robert Literman
I am a third year PhD student in the Ecology and Evolutionary Biology program. I am interested in the evolution and functional
basis of sex determination in reptiles. I am also a herp enthusiast,
and have worked with reptiles in Costa Rica and New Zealand.
Bob’s Website
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Srihari Radhakrishnan
I
am a second year Ph.D. student in the Bioinformatics & Computational
Biology program. I am interested in the transcriptomic analysis of gonadal
development in turtles.
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Emily Barks
I am a first year Master's student in the Interdepartmental Genetics
program. I am interested in evolutionary developmental biology
of sex determination in turtles, particularly the involvement
of epigenetics processes.
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Dr. Daleen Badenhorst
I
am a postdoctoral fellow. My previous work focused on the Rattus complex and its role as a reservoir for human pathogens using a molecular cytogenetic, phylogenomic and gene expression approach. I am now working on a phylogenomics project
to study the evolution of sex chromosomes and sex-linked genes in turtles.
My work is funded by the National Science Foundation (MCB 0815354
to N. Valenzuela and S.V. Edwards).
Daleen's
Website
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Dr. Daniel Janes
I
am a postdoctoral fellow. I am an evolutionary geneticist interested
in the evolution of sex-determining mechanisms and sex chromosomes.
My work is funded by the National Science Foundation (MCB 0815354
to N. Valenzuela and S.V. Edwards).
Dan's
Website
Janes, D.E., Valenzuela N., Ezaz T., Amemiya C., and Edwards S.V. 2011. Sex chromosome evolution in Amniotes: applications for bacterial artificial chromosome libraries. Journal of Biomedicine and Biotechnology Vol 2011, doi:10.1155/2011/132975
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Former Lab Members
Dr. Claudia Ceballos
I
completed my Ph.D. in the EEB program at ISU in 2010. I am interested
in understanding the causes and consequences of phenotypic evolution.
My PhD work focused on phenotypic plasticity of body growth and
its effect on the evolution of sexual size dimorphism in Podocnemis
expansa and Chelydra serpentina and the evolution of
Rensch's rule in turtles. My work was funded by the National Science
Foundation (DEB 0808047) and the Turtle Conservation Fund, to
N. Valenzuela (PI) and C Ceballos (CoPI).
I am now a Lecturer Faculty at the Veterinary Medicine Program
of the University of Antioquia, Colombia.
Claudia’s Website
Ceballos, C. and Valenzuela, N. 2011. The role of sex-specific plasticity in shaping sexual dimorphism in a long-lived vertebrate, the snapping turtle Chelydra serpentina. Evolutionary Biology 38: 163-181.
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Dr. Jennifer Neuwald
I
am a postdoctoral fellow. My previous work focused on the temporal
changes in population genetic dynamics of the eastern collared
lizard, Crotaphytus collaris collaris, in response to
forest fire management. I am now working on an eco-genomics project
to study the effect of fluctuating temperature on the expression
of genes involved in gonadogenesis in TSD turtles.
My work is funded by the National Science Foundation (IOS 0743284
to N. Valenzuela).
Jennifer's
Website
Neuwald
J.L. and Valenzuela N. 2011. The Lesser Known Challenge of Climate
Change: Thermal Variance and Sex-Reversal in Vertebrates with
Temperature-Dependent Sex Determination. PloS ONE
6(3): e18117. doi:10.1371/journal.pone.0018117
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Dr. Jennifer Deitloff
I
completed my Ph.D. in the EEB program at ISU in 2008. My work
focused on the ecological processes responsible for species co-ocurrence
patterns in two species of Plethodon salamanders. I was
co-advised by Dr. Dean Adams.
I am now a Postdoctoral Scholar in the Department of Biological
Sciences at Auburn University.
Jennifer's
Website
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Dr. Tibisay Escalona
I
was an NSF postdoctoral fellow. I am very interested in the ecology,
life history evolution and conservation of freshwater turtles
in the Neotropics. I worked on the metapopulation genetic analysis
of Podocnemis unifilis turtles in South America.
My work was funded by the National Science Foundation (DBI 0511958
to T. Excalona), and the Scott Neotropical Fund from the Cleveland
Zoo (to N. Valenzuela [PI] and T. Escalona [CoPI]).
I am currently a fellow at the laboratory of Ecotoxicology, Genomics
and Evolution at CIMAR in Portugal.
Tibisay’s Website
Escalona, T., Engstrom T.N., Hernandez
O.E., Bock B.C., Vogt R.C. and Valenzuela N. 2009. Population genetics
of the endangered South American freshwater turtle, Podocnemis
unifilis, inferred from microsatellite DNA data. Conservation
Genetics. DOI 10.1007/s10592-008-9746-3
Escalona, T., Adams, D.C., and Valenzuela,
N. 2009. Nesting ecology in the freshwater turtle Podocnemis unifilis:
spatiotemporal patterns and inferred explanations. Functional
Ecology DOI 10.1111/j.1365-2435.2009.01562.x
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Dr. Takahito Shikano
Postdoctoral
associate. I worked on the molecular evolution of sex related
genes across reptiles and other vertebrates that possess contrasting
sex determining mechanisms, in order to shed light on the evolution
of sex determination.
I am now a Postdoc in the Ecological Genetics Research Unit at
the University of Helsinki.
Taka's
Website
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Valenzuela, N.,
LeClere A.R, and Shikano T. 2006. Comparative expression of steroidogenic
factor 1 in Chrysemys picta and Apalone mutica
turtles with environmental and genotypic sex determination.
Evolution and Development 8 (5): 424-432.
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Valenzuela, N.
and Shikano T. 2007. Embryological ontogeny of Aromatase gene expression
in Chrysemys picta and Apalone mutica turtles:
comparative patterns within and across temperature-dependent
and genotypic sex-determining mechanisms. Development, Genes and Evolution 217:
55-62.
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Pedro Martinez
I
was a Ph.D. student in the Ecology and Evolutionary Biology Program (2006-2008) and the Genetics Program
(2008-2009) at ISU. I worked on sex chromosome evolution in turtles, particularly
in discovering a novel XX/XY system in the Australian chelid Emydura
macquarii. I am now a graduate student in Veterinary Medicine
at ISU.
Martinez, P., Ezaz T., Valenzuela,
N., Georges, A., and Graves J.A.M. 2008. An XX/XY heteromorphic sex
chromosome system in the Australian chelid turtle Emydura
macquarii, a new piece in the puzzle of sex chromosome evolution
in turtles. Chromosome Research: 16(6): 815-825. DOI 10.1007/s10577-008-1228-4.
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Andrea R. LeClere
I
graduated from the undergraduate Genetics program at ISU. For my
honors thesis I worked during 2004-2005 on a project aimed to compare the expression
profiles of sex genes (genes involved in sex differentiation)
between turtles with temperature-dependent sex determination (Chrysemys
picta) and turtles with genotypic sex determination (Apalone
mutica) incubated under identical conditions. We were searching
for key differences to understand the mechanics of both sex determining
systems.
I am now a PhD student in the Molecular, Cellular and Structural
Biology program at the University of Minnesota.
- Valenzuela, N., LeClere A.R, and
Shikano T. 2006. Comparative expression of steroidogenic factor 1 in
Chrysemys picta and Apalone mutica turtles with environmental
and genotypic sex determination. Evol. Dev. 8 (5): 424-432.
- LeClere A.R. and N. Valenzuela.2005.
Comparative gene expression of multiple sex-determining genes
in TSD and GSD turtles. Joint Meeting of the Society for the Study
of Amphibians and Reptiles and the Herpetologists' League, Tampa,
Florida.
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Barbara Kagima
 I was a Biology undergraduate at ISU, and during 2002-2005 I worked on population genetics of Podocnemis
unifilis turtles from Colombia and Peru, and on maternal-effect
genes related to sex differentiation in Chrysemys picta turtles
from North America. I completed my Master’s in 2008 in the EEB program
at ISU working on Wildlife Management with Dr. Sue Fairbanks. I
am now a PhD student at the University of Nebraska Lincoln.
- Kagima, B. and N. Valenzuela. 2005. Maternal
effect genes for sex determination in painted turtles, Chrysemys
picta. Joint Meeting of the Society for the Study of Amphibians
and Reptiles and the Herpetologists' League, Tampa, Florida.
- Kagima, B., Valenzuela, N., Engstrom,
T., and Bock, B. 2004. Preliminary population genetic study of
the yellow spotted Amazon river turtle (Podocnemis unifilis)
using microsatellite DNA data. Annual Meeting of the Society of
Integrative and Comparative Biology, New Orleans, Louisiana.
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Sonia Morrone and Anthony Siegle
  We were ITA
interns at the Valenzuela Lab during 2008-2009, and were Biology majors at ISU. We worked on
developmental biology and the effect of incubation temperature and posthatching environment on growth of snapping turtles, Chelydra serpentina.
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Morrone S. and Siegle A. 2009. Effects of environment on growth. Iowa Academy of Sciences Annual Meeting,Des Moines, IA.
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Katherine L. O'Shaughnessy
 I
was a summer intern with the ITA
program at the Valenzuela Lab and the REU
in Molecular Biotechnology and Genomics at ISU in 2009. I worked on
developmental biology and expression profiling of genes involved
in sex determination in turtles. I am now a Ph.D. student at the
University of Florida where I am studying vetebrate EvoDevo.
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O’Shaughnessy
K, Valenzuela, N, Neuwald, N, Literman, R, Manternach, T, Harris,
A. 2010. The genomics of temperature dependent sex determination in
Chrysemys picta. Experimental Biology FASEB Annual Meeting,
Anaheim, CA. Poster & Invited oral presentation - Winner of
NSF travel grant for undergraduates - Winner of "ASBMB's Best
Poster Theme" in the category of Systems Biology, Synthetic
Biology, and Signal Transduction.
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O'Shaughnessy
K, Valenzuela, N, Neuwald, J, Literman, R, Manternach, T, Harris,
A. 2010. The Genetic mechanism of temperature-dependent sex determination
in the painted turtle. Capital University Research Symposium,
Columbus, OH. Winner of Capital University's endowed "Bruning
Award" for excellence in research.
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Kevin Wenceslao
 I
was an ITA
intern at the Valenzuela Lab during 2010-2011. I am a Biology major at ISU. I worked on
developmental biology and the effect of incubation temperature on growth of painted turtles posthatching.
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Wenceslao K, Literman R, Neuwald J, and Valenzuela N. 2011. The effect of temperautre on sex determination and fitness in painted turtles. Iowa Academy of Sciences Annual Meeting,
Waverly, IA.
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Chris Chandler
I
was a Ph.D. rotation student in the Ecology and Evolutionary Biology
program. I am interested in the evolution of sex determination.
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Jeffrey Sander
I
was a Ph.D. rotation student from the Bioinformatics & Computational
Biology program. I worked on sex ratio evolution models.
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Jacqueline Farrel
I
was a MSc rotation student from the Interdepartmental Genetics
program. I worked on the molecular evolution of genes involved
in sex determination.
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William Pett
I
was a Ph.D. rotation student from the Bioinformatics & Computational
Biology program. I worked on the transcriptomic analysis of gonadal
development in turtles.
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