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Dr. Nicole Valenzuela Department of Ecology, Evolution, and Organismal Biology

Iowa State University

251 Bessey Hall. Ames, IA 50011

(515) 294-1285

nvalenzu@iastate.edu

 

 

 
 

Curriculum Vitae

Nicole Valenzuela

 

 

Education

Ph.D. 1999. State University of New York at Stony Brook. Ecology and Evolution. Advisor: Dr. Charles H. Janson.

M.A. 1995. State University of New York at Stony Brook. Applied Ecology. Advisor: Dr. Charles H. Janson

B.Sc. 1991. Universidad de Los Andes, Bogotá, Colombia. Biology.

 

Positions Held

2010- present: Associate Professor, Dept. of Ecology, Evolution, and Organismal Biology, Iowa State University.

2009-2010 Visiting Assistant Professor, Dept. of Evolutionary Biology, Università degli Studi di Firenze, Florence, Italy.

2004- 2010 Assistant Professor, Dept. of Ecology, Evolution, and Organismal Biology, Iowa State University.

2001- 2004 Adjunct Assistant Professor and Associate Scientist, Dept. of Zoology and Genetics / EEOB, Iowa State University, Ames, Iowa.

2000-2001 Affiliate Assistant Professor, Dept. of Zoology and Genetics, Iowa State University.

1999-2000 Postdoctoral Associate, Dept. of Zoology and Genetics, Dr. Fredric Janzen, Iowa State University.

2003-2013 Faculty Member, Center for Integrative Animal Genomics, Iowa State University.

2001- present: Faculty Member, Interdepartmental Programs in Ecology and Evolutionary Biology (EEB), Genetics (IG), and Bioinformatics and Computational Biology (BCB) & Multidisciplicary Graduate Education Training (MGET), Iowa State University.

 

External Grants

2013-2016 National Science Foundation – Eukaryotic Genetics MCB 1244355– “Genome repatterning underlying the co-evolution of diploid number and sex determination in turtles”

2013-2015 National Science Foundation – DEB – DISSERTATION RESEARCH: The genome-wide occupancy and thermosensitivity of histone variant H2A.Z in embryonic Chrysemys picta, a turtle with temperature-dependent sex determination. (Co-PI: R. Literman).

2009-2011 Colciencias (Colombia’s National Science Foundation) – “Maternal and paternal effects on hatchling sex ratio and fitness in the riverine turtle Podocnemis lewyana”. Co-PI with Grupo Herpetológico de Antioquia, Colombia.

2009-2012 National Science Foundation – Eukaryotic Genetics MCB 0815354 “COLLABORATIVE RESEARCH: Sex Chromosome Evolution in Turtles” PI: N. Valenzuela, CoPI: S.V. Edwards (Harvard University).
2011 • NSF REU supplement (MCB 1112116)
2012 • NSF REU supplement (MCB 1233241)
2012 • NSF Supplement (MCB 1233234)

2008-2011 National Science Foundation – Developmental Systems IOS 0743284 “Gene expression response to naturally fluctuating temperature in turtles with alternative sex determining mechanisms”
2008 • NSF RET supplement (IOS 0824550)
2008 • NSF REU supplement (IOS 0826664)
2009 • NSF RET supplement (IOS 0924290)
2009 • NSF REU supplement (IOS 0925486)
2010 • NSF RET supplement (IOS 1032265)

2008-2011 National Science Foundation – Evolutionary Genetics DEB 0808047 “DISSERTATION RESEARCH: Phenotypic plasticity, sexual size dimorphism and Rensch's rule in freshwater turtles” (Co-PI: C. Ceballos)

2008-2009 National Science Foundation – Organism-Environment Interactions IOS 0809547 “Symposium: Reptile genomics and evolutionary genetics”. (CoOrganizers: D.E. Janes, C.L. Organ).

2006-2007 Turtle Conservation Fund – “Environmental effects on fitness of embryos and hatchlings of the endangered Arrau River Turtle, Podocnemis expansa, with important conservation implications”, CoPI with C. Ceballos.

2006-2007 Scott Neotropical Fund, Cleveland Zoo – “Metapopulation Genetics of the freshwater turtle Podocnemis unifilis”, Co-PI with T. Escalona

2003-2004 Lincoln Park Zoo –“Effect of nest transplant on hatchling sex and viability: an evaluation of conservation practices for the giant river turtle (Podocnemis expansa) in Venezuela” (Co-P.I., with C. Peñaloza and G. Barreto).

1998-2000 National Science Foundation. – Ecological & Evolutionary Physiology IOS 9800679 “Dissertation Research: Temperature-dependent sex determination in Podocnemis expansa”. (PI: C. Janson).

1996-1998 Colciencias (Colombia’s National Science Foundation) – “Temperature-dependent sex determination and population structure of Podocnemis expansa from Colombian Amazonia”.

1996-1998 PADI Foundation. –“Determination of Multiple Paternity in the Giant River Turtle Podocnemis expansa”.


Teching Experience

2011 Graduate Seminar (EEOB 590B) Extended Evolutionary Synthesis, Iowa State University

2010 Undergraduate Seminar (Biol 495) Evolutionary Ecology of Sex, Iowa State University

2008, 2009, 2012, 2013 Honors Research (HON 280H VM), Iowa State University

2007 Biology Internship (Biol 494), Iowa State University

2007-present: Individual Student Biology Research (Biol 490R), Iowa State University

2008- present: EEB Graduate Research (Genet 699), Iowa State University

2005- present: EEB Graduate Research (EEB 699), Iowa State University

2007 Graduate Seminar, Evolutionary Ecology of Sex (EEOB 590B), Iowa State University

2006, 2008, 2012 Evolutionary Ecology (EEOB 514), Iowa State University

2004- present (every year) Environmental Biology (Biol 173, former Biol 123), Iowa State University

2000- 2001 Undergraduate Mentoring in Environmental Biology Seminar (program sponsored by NSF), Dept. of Zoology and Genetics, Iowa State University.

1999-2000 General Biology Laboratory, Dept. of Zoology and Genetics, Iowa State University.

1997-1998 Teaching Assistant: General Ecology, Ecology Laboratory, Ecology. Dept. of Ecology and Evolution, SUNY at Stony Brook, New York.

1995 Teaching Assistant: General Ecology, Lab instructor of Cat Anatomy, Elementary Organismic Biology. Dept. of Ecology and Evolution, SUNY at Stony Brook, NY

1991 Laboratory Instructor: Genetics. Universidad de Los Andes, Colombia.

 

Awards, Honors and Scholarships

2004 National Society of Collegiate Scholars Faculty of the Year Student Nominee.

1997 Department of Ecology and Evolution, SUNY at Stony Brook. Outstanding Graduate Student Presentation Award.

1995 Fulbright Commission. Exceptional Research Award.

1993 Fulbright Commission, Amazon Basin Program. Scholarship.

1986 José Antonio Galán Fund, Colombia. Scholarship. 1986 ICETEX, Colombia. Scholarship

 

Publications

 


COPYRIGHT NOTICE: Reprints of published articles are provided as a service to enhance accessibility and the exchange of information. In downloading, you agree to comply with United States copyright law (Title 17, United States Code), such that the reprints are not to be "used for any purpose other than private study, scholarship, or research." All copyrights remain with the original publishers of the articles. Please make only a single copy of any article, for personal use only.

 

Updated 2/24/2014

  

2014

53. Ceballos CP, OE Hernández and N Valenzuela. 2014. Divergent sex-specific plasticity in long-lived vertebrates with contrasting sexual dimorphism. Evolutionary Biology 41:81–98 PDF.

2013

52. Weiner SA, DA Galbraith, DC Adams, N Valenzuela, FB Noll, CM Grozinger, and AL Toth. 2013. A survey of DNA methylation across social insect species, life stages, and castes reveals abundant and caste-associated methylation in a primitively social wasp. Naturwissenschaften 100: 795-799 PDF.

51. Shaffer HB, P Minx, DE Warren, AM Shedlock, RC Thomson, N Valenzuela, J Abramyan, D Badenhorst, KK Biggar, GM Borchert, CW Botka, RM Bowden, EL Braun, AM Bronikowski, BG Bruneau, LT Buck, B Capel, TA Castoe, M Czerwinski, KD Delehaunty, SW Edwards, CC Fronick, MK Fujita, L Fulton, TA Graves-Lindsey, RE Green, W Haerty, R Hariharan, LW Hillier, AK Holloway, D Janes, FJ Janzen, C Kandoth, L Kong, APJ de Koning, Y Li, R Literman, SE McGaugh, L Mork, M O’Laughlin, RT Paitz, DD Pollock, CP Ponting, S Radhakrishnan, BJ Raney, JM Richman, J StJohn, T Schwartz, A Sethuraman, PQ Spinks, KB Storey, N Thane, T Vinar, LM Zimmerman, WC Warren, ER Mardis, and RK Wilson. 2013. The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage. Genome Biology. DOI:10.1186/gb-2013-14-3-r28. PDF

50. Janes DE, Elsey RM, Langan EM, Moore B, Edwards SV and N Valenzuela. 2013. Sex-biased expression of sex-differentiating genes Foxl2 and Fgf9 in American alligators, Alligator mississippiensis. Sexual Development. 7: 253–260 PDF.

49. Badenhorst, D., R. Stanyon, T. Engstrom, and N. Valenzuela.2013. A ZZ/ZW microchromosome system in the spiny softshell turtle, Apalone spinifera reveals an intriguing sex chromosome conservation in Trionychidae. Chromosome Research. 12(2): 137-147. DOI 10.1007/s10577-013-9343-2 PDF.

48. Valenzuela N., J. Neuwald, and R. Literman. 2013. Transcriptional evolution underlying vertebrate sexual development. Developmental Dynamics. 242:307–319. DOI: 10.1002/dvdy.23897 PDF.

47. Ceballos C.P., Adams D.C., Iverson J.B., and Valenzuela N. 2013. Phylogenetic patterns of sexual size dimorphism in turtles and their implications for Rensch´s rule. Evolutionary Biology 40: 194-208. DOI: 10.1007/s11692-012-9199-y. PDF.

2012

46. Valenzuela N. and Ceballos C.P. 2012. Evolución y mecanismos de determinación sexual en tortugas. In: Biología y Conservación de las Tortugas Continentales de Colombia. Paez V.P. Editor. Serie Editorial “Recursos Hidrobiológicos y Pesqueros de Colombia”, Instituto de Investigación de Recursos Biológicos Alexander von Humboldt, Bogotá, Colombia. PDF.

 

 

2011

45. Bachtrog D., Kirkpatrick M, Mank, J.E., McDaniel S.F., Pires J.C., Rice W. and Valenzuela N. 2011. Are all sex chromosomes created equal? Trends in Genetics 27 (9): 350-357. PDF.

44. Ceballos, C. and Valenzuela, N. The role of sex-specific plasticity in shaping sexual dimorphism in a long-lived vertebrate, the snapping turtle Chelydra serpentina. Evolutionary Biology 38: 163-181. PDF

43. Neuwald J.L. and Valenzuela N. 2011. The Lesser Known Challenge of Climate Change: Thermal Variance and Sex-Reversal in Vertebrates with Temperature-Dependent Sex Determination PloS ONE 6(3): e18117. doi:10.1371/journal.pone.0018117. PDF

42. Valenzuela N. and Adams D.C. 2011. Chromosome number and sex determination co-evolve in turtles Evolution 65: 1808-1813. PDF

41. Janes, D.E., Valenzuela N., Ezaz T., Amemiya C., and Edwards S.V. 2011. Sex chromosome evolution in Amniotes: applications for bacterial artificial chromosome libraries. Journal of Biomedicine and Biotechnology Vol 2011, doi:10.1155/2011/132975 PDF.

2010

40. Valenzuela, N. 2010. Co-evolution of genomic structure and selective forces underlying sexual development and reproduction. Cytogenetics nd Genome Research 127:232–241PDF.

39. Valenzuela, N. 2010. Multivariate expression analysis of the gene network underlying sexual development in turtle embryos with temperature-dependent and genotypic sex determination. Sexual Development 4 (1-2): 39-49 PDF.

 

2009

38. Valenzuela, N. 2009. The painted turtle, Chrysemys picta: A model system for vertebrate evolution, ecology, and human health. Cold Spring Harbor Protocols 2009: DOI:10.1101/pdb.emo124 PDF.

37. Valenzuela, N. 2009. Egg incubation and collection of painted turtle embryos. Cold Spring Harbor Protocols 2009 DOI:10.1101/pdb.prot5238 PDF.

36. Escalona, T., Adams, D.C., and Valenzuela, N. 2009. Nesting ecology in the freshwater turtle Podocnemis unifilis: spatiotemporal patterns and inferred explanations. Functional Ecology 23: 826-835 PDF.

35. Escalona, T., Engstrom T.N., Hernandez O.E., Bock B.C., Vogt R.C. and Valenzuela N. 2009. Population genetics of the endangered South American freshwater turtle, Podocnemis unifilis, inferred from microsatellite DNA data. Conservation Genetics 10: 1683–1696 PDF.

 

2008

34. Chinsamy, A. and Valenzuela, N. 2008. Skeletochronology of the endangered side-neck turtles Podocnemis expansa. South African Journal of Science 104(7/8): 311-314 PDF

33. Martinez, P., Ezaz T., Valenzuela, N., Georges, A., and Graves J.A.M. 2008. An XX/XY heteromorphic sex chromosome system in the Australian chelid turtle Emydura macquarii, a new piece in the puzzle of sex chromosome evolution in turtles. Chromosome Research 16(6): 815-825 PDF

32. Valenzuela, N. 2008. Sexual development and the evolution of sex determination. Sexual Development 2(2): 64-72. PDF

31. Valenzuela, N. 2008. Evolution of the gene network underlying gonadogenesis in turtles with temperature-dependent and genotypic sex determination. Integrative and Comparative Biology 48 (4): 476-485. PDF Full Text

30. Janes D.E., Organ C., and Valenzuela N. 2008. New resources inform study of genome size, content and organization in non-avian reptiles. Integrative and Comparative Biology 48(4): 447-453. PDF Full Text

29. Valenzuela, N. 2008. Relic thermosensitive gene expression in a turtle with genotypic sex determination. Evolution 62-1: 234-240. PDF

2007

 28. McGaugh, S.E., Alacs E.A., Edwards S.V., Feldman C.R., Georges A., Sites, J.R.Jr., Valenzuela N. 2007. From molecules to organisms: Research applications of modern genetic tools for turtle biology and conservation. Chelonian Research Monographs 4: 47-72. PDF

27. Valenzuela, N. and Shikano T. 2007. Embryological ontogeny of Aromatase gene expression in Chrysemys picta and Apalone mutica turtles: comparative patterns within and across temperature-dependent and genotypic sex-determining mechanisms. Development, Genes and Evolution 217: 55–62. PDF

 

2006

 26. Valenzuela, N., LeClere A., and Shikano T. 2006. Comparative expression of steroidogenic factor 1 in Chrysemys picta and Apalone mutica turtles with environmental and genotypic sex determination. Evolution and Development 8 (5): 424-432 PDF

25. Ezaz T., Valenzuela, N., Gruetzner F., Miura I., Burke R., Georges, A. and Graves J.M. 2006. An XX/XY sex microchromosome system in a freshwater turtle, Chelodina longicollis (Testudines : Chelidae) with genetic sex determination. Chromosome Research 14:139-150 PDF

24. Pearse, D.E., A.D. Arndt, N. Valenzuela, B.A. Miller, V. Cantarelli, J.W. Sites, Jr. 2006. Estimating population structure under non-equilibrium conditions in a conservation context: Continent-wide population genetics of the giant Amazon river turtle Podocnemis expansa (Chelonia; Podocnemidae). Molecular Ecology 15: 985-1006  PDF

23. Valenzuela, N. 2006. (Book Review). Incubation of Reptile Eggs: Basics, Guidelines, Experiences, by Gunther Kohler. Quarterly Review of Biology 81:290-291. PDF

 

2004

 22. BOOK: Valenzuela, N. and V. Lance, Eds. 2004. Temperature Dependent Sex Determination in Vertebrates. Smithsonian Books. Washington D.C PDF INFO

21. Valenzuela, N., D.C. Adams, R.M. Bowden, and A.C. Gauger 2004. Geometric morphometric sex estimation for hatchling turtles: a powerful alternative for detecting subtle sexual shape dimorphism. Copeia. 2004(4): 735–742 PDF

20. Valenzuela, N. 2004. Evolution and maintenance of temperature-dependent sex determination. Pp. 131-147. In Valenzuela, N. and V. Lance, Eds. Temperature Dependent Sex Determination in Vertebrates. Smithsonian Books. Washington D.C PDF

19. Valenzuela, N. 2004. Temperature-dependent sex determination. Pp. 211-227. In Deeming D.C. Ed. Reptilian Incubation: Environment & Behaviour. Nottingham University Press. PDF

 

2003

 18. Valenzuela, N., D.C. Adams, and F.J. Janzen. 2003. Pattern does not equal process: Exactly when is sex environmentally determined? American Naturalist 161 (4): 676-683  PDF

17. Kagima, B. W., N. Valenzuela, T. Engstrom, B. Bock. 2003. Preliminary population genetic study of the yellow spotted Amazon river turtle (Podocnemis unifilis) using microsatellite DNA data. Integrative and Comparative Biology 43: 1025-1025.

 

2001

 16. Milne-Morjan, C. and N. Valenzuela. 2001. Is ground-nuzzling by female turtles associated with soil surface temperatures? Journal of Herpetology 35(4): 668-672  PDF

15. Valenzuela, N. and F. J. Janzen. 2001. Nest-site philopatry and the evolution of temperature-dependent sex determination. Evolutionary Ecology Research 3: 779-794  PDF

14. Valenzuela, N. 2001. Constant, shift and natural temperature effects on sex determination in Podocnemis expansa turtles. Ecology 82(11): 3010–3024  PDF

13. Valenzuela, N. 2001. Maternal effects on life history traits in the Amazonian giant river turtle Podocnemis expansa. Journal of Herpetology 35(3): 368-378 PDF

12. Valenzuela, N. 2001. Genetic differentiation among nesting beaches in the highly migratory giant river turtle (Podocnemis expansa) from Colombia. Herpetologica 57(1): 48-57   PDF

 

2000

 11. Valenzuela, N. 2000. Multiple paternity in side-neck turtles Podocnemis expansa: evidence from microsatellite DNA data. Molecular Ecology 9: 99-106 PDF

 

1997

 10. Adams, D. C., M. S. Di Bitetti, C. H. Janson, L. B. Slobodkin, and N. Valenzuela. 1997.  An “audience effect” for ecological terminology: use and misuse of jargon. Oikos 80:632-636 PDF

9. Valenzuela, N, E. Martínez, and R. Botero.  1997. Field study of sex determination in Podocnemis expansa from Colombian Amazonia. Herpetologica 53(3):390-398   PDF

 1995

 8. Valenzuela, N, E. Martínez, and R. Botero. 1995. Preliminary model of sex determination of Podocnemis expansa from Colombian Amazonia. Proceedings of the International Congress of Chelonian Conservation and Biology. Pp. 276-278.

1992

 7. Lance,V.A., N. Valenzuela and P. von Hildebrand. 1992. A hormonal method to determine the sex of hatchling giant river turtles, Podocnemis expansa. Application to endangered species research. American Zoologist 32:16A PDF

 

Undergraduate work (1990-1994)

 

6. Valenzuela, N. 1994. Early behavioral development of three wild infant Cebus apella in Colombia. Current Primatology, Volume II. Social Development, Learning and Behaviour. (Roeder, J.J., Thierry, B., Anderson, J.R. and N. Herrenschmidt, eds.). Selected Proceedings of the XIVth Congress of the IPS, Strasbourg, France, 1992. Pp. 297-302.

5. Valenzuela, N. 1993. Social contacts between infants and other group members in the wild Cebus apella. Field Studies of New World Monkeys at La Macarena, Colombia 8: 1-9 PDF

4. Valenzuela, N. 1992. Early development of three wild infant Cebus apella at La Macarena, Colombia. Field Studies of New World Monkeys at La Macarena, Colombia 6: 15-23  PDF

3. Espinel A. and N. Valenzuela. 1991. Adaptaciones genéticas a la malaria en poblaciones afroaborígenes del Pacífico Colombiano. Revista de Antropología y Arqueología. 7:117-130 PDF

2. Groot de Restrepo, H., A. Espinel, N. Valenzuela, D. Sicard, P. Angulo, and D. Nieto. 1991. Variabilidad Genética en el Género Cebus en Colombia. Proceedings of the II Congreso de Primatología, Barranquilla, Colombia.

1. Espinel A., N. Valenzuela, A. Fajardo, J. Umaña, and G. Quintero. 1990. Breve reseña de las actividades primatológicas en Colombia. Boletín Primatología Latinoamericana 2(1):62-68.

 

COPYRIGHT NOTICE: Reprints of published articles are provided as a service to enhance accessibility and the exchange of information. In downloading, you agree to comply with United States copyright law (Title 17, United States Code), such that the reprints are not to be "used for any purpose other than private study, scholarship, or research." All copyrights remain with the original publishers of the articles. Please make only a single copy of any article, for personal use only.