Valenzuela Lab
 
Cpicta
NV

Dr. Nicole Valenzuela Department of Ecology, Evolution, and Organismal Biology

Iowa State University

251 Bessey Hall. Ames, IA 50011

(515) 294-1285

nvalenzu@iastate.edu

NSF

RESEARCH OVERVIEW We are interested in studying how ecology affects the structure, function, and evolution of the genome and its role in the development and evolution of complex phenotypes. This helps us understand the evolution of biological diversity and how it responds to environmental change.

 

 
 

News And Events Our latest pubs and more

A lengthy solution to the optimal propagule size problem in the large-bodied South American freshwater turtle, Podocnemis unifilis. Evolutionary Ecology. 2018. In Press

Chromosomal context affects the molecular evolution of sex-linked genes and their autosomal counterparts in turtles and other vertebrates. Journal of Heredity. 2017. Preprint

MeDIPseq and nCpG analyses illuminate sexually dimorphic methylation of gonadal development genes with high historic methylation in turtle hatchlings with temperature-dependent sex determination. Epigenetics & Chromatin 2017. PDF

Development of sexing markers in Glyptemys insculpta and Apalone spinifera turtles uncovers an XX/XY sex-determining system in the critically-endangered bog turtle Glyptemys muhlenbergii. Conservation Genetic Resources. 2017. Full Text

Transcriptomic responses to environmental temperature by turtles with temperature-dependent and genotypic sex determination assessed by RNAseq inform the genetic architecture of embryonic gonadal development PLoS ONE. 2017. PDF

Discovery of youngest sex chromosomes reveals first case of convergent co-option of ancestral autosomes in turtles. Chromosoma 2017. PDF

Sex determination and the birth and death of species. Ecology and Evolution 2016. PDF

Cytogenetic insights into the evolution of chromosomes and sex determination reveal striking homology of turtle sex chromosomes to amphibian autosomes. Cytogenetic and Genome Research 2016. PDF

GRADUATE AND POSTDOCTORAL POSITIONS Positions are available for individuals interested in evolutionary biology, sex determination, evo-devo, chromosome and genome evolution, or climate change. Click here for details.

Sex Determination Evolution and Regulation of Developmental Networks

Embryos

Why do organisms vary so remarkably in the ways they produce males and females? Our work focuses on comparative evolutionary and ecological genomics related to the evolution of developmental pathways, particularly those that underlie the development of the sexual phenotype.

Phylogenomics Sex Chromosomes and Genome Organization

Chromosomes

What are the causes and consequences of chromosome evolution? We are studying (a) the evolution of sex chromosomes and the genes they contain, plus (b) the genome rearrangements responsible for changes in diploid number across turtles and their association with transitions in sex determination.

Links

ITA
TSDbook
EEOB
ISU
 
treeofsex
Tree of Sex Database Paper
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