Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology

Nikolau Research Group

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Dr. Nikolau is the Frances M. Craig Professor of Biochemistry at Iowa State University where he has taught and conducted research since 1988. He was awarded his Ph.D. in Biochemistry at Massey University, New Zealand, in 1982, and conducted postdoctoral research at the University of California, Davis, and the University of Utah before joining the faculty of Iowa State University. Dr. Nikolau's research interests focus on the biochemistry and molecular biology of biotin and biotin-containing enzymes and the regulation of plant lipid metabolism.

Nikolau group research is conducted in the Molecular Biology Building and the 4th floor of the Biorenewables Research Laboratory (BRL 4th).


Faculty Membership:


The Nikolau Research Group

Research in the Nikolau Group is focused on the comprehensive understanding of metabolism. The lab is particularly focused on the discovery and characterization of novel metabolic processes, and the associated biocatalysts, utilizing expanding genomics resources as the starting point for these endeavors.

The past decade has seen an explosion of genomics datasets, which have revolutionized the way biological systems are defined. Yet the majority of the gene sequences that are deposited at databases are ambiguously annotated relative to biochemical functionality.  These gaps in knowledge therefore offer opportunities for novel discoveries that can be used to generate innovative metabolic solutions to societally defined issues.

These research activities are providing opportunities for research-based education and training of undergraduate and graduate students, as well as post-doctoral researchers.

News & Updates

Associate scientist accepts new position
April 14, 2015
Congratulations and all best wishes to Zhihong Song, associate scientist and assistant manager of the W.M. Keck Metabolomics Research Laboratory, who has accepted a position with the Food and Drug Administration in Washington, DC. The Nikolau research group honored Song at a farewell potluck on April 7.

Plant Lipids Conference
February 9,2015

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Nikolau Research Group members Liza Alexander, Alexis Campbell, Jennifer Chmliewski, Kayla Flyckt, Xin Guan, Adarsh Jose and Basil Nikolau participated in the "Plant Lipids: Structure, Metabolism & Function" Gordon Research Conference held February 1-6 in Galveston, TX.

Stephanie Ikediobi joins Nikolau group
February 9, 2015
Stephanie Ikediobi joined the Nikolau Research Group at the beginning of Spring semster. Stephanie is an interdepartmental genetics MS student, whose research interests include epigenetics, nutrient-gene interactions and metabolism. Welcome aboard, Stephanie!

Yandeau-Nelson promoted to Assistant Professor
September 22, 2014
Marna Yandeau-Nelson was recently promoted to Assistant Professor in the Department of Genetics, Development and Cell Biology. Along with assuming teaching duties, she has established her own independent research group. Yandeau-Nelson had previously served as Associate Scientist with the Nikolau reasearch group. Congratulations, Marna!

News & Updates Archives