Influenza Vaccine Research Study in Older Adults
Can exercise and/or psychosocial factors influence
the immune response to influenza vaccine?
Researchers at Iowa State University will try to answer this question
with a 3-year NIH-funded clinical trial.
Health behaviors (diet, exercise, psychosocial factors) may influence
resistance to disease. As people age, immune function often declines,
leaving older adults more susceptible to infection. Due to this
decline in immune function, vaccines may not be as effective. Our
research group is interested in finding out if we can improve immunity
and vaccine effectiveness among older adults by changing health
habits (practicing regular exercise, reducing stress, etc).
Our preliminary studies over the past several years are promising
in terms of improving immune response to influenza immunization
in older adults. Over the next 3 years, we plan to enroll approximately
100 adults in an exercise program. Through our research, we hope
to find ways to improve resistance to infection in the older adult