-
Ph.D. in Bioinformatics and Computational
Biology, Iowa State University, 2008
- M.S. in Statistics,
Iowa State University, 2005
-
M.Phil. in
Biochemistry,
Chinese University of Hong Kong, 2001
- B.S. in
Biology; B.E. in Economics and Management, University of Science and Technology of China,
1998
- Statistical Scientist, Crop Biometrics, Breeding Technology, Monsanto
Company, 2008-Present
-
Research Assistant in Bioinformatics and Biological Statistics,
Iowa State University,
2002-2008
- Research Assistant in Molecular Biology and
Biochemistry, Chinese University of Hong Kong, 1999-2001
- L. Yang, G. Song and R. L.
Jernigan. "Comparisons of experimental and computed protein anisotropic
temperature factors",
Proteins: Structure, function, and Bioinformatics, submitted.
- L. Yang,
G. Song, A. Carriquiry and R. L. Jernigan. "Close correspondence between the
motions from principal component analysis of multiple HIV-1
protease structures and elastic network modes" (2008), Structure,
16: 321-330.
[Link]
- L. Yang,
G. Song and R. L. Jernigan. "How well can we understand large-scale protein
motions using normal modes from elastic network models?" (2007),
Biophys. J., 93: 920-929.
[Link]
- R. L. Jernigan, L. Yang, O. Kurkcuoglu, G. Song and P. Doruker.
"Elastic network
models of coarse-grained proteins are effective for studying the structural control exerted over their dynamics" in
"Coarse-graining of condensed phase and biomolecular systems", Ed. G. Voth, Taylor and Francis Group, LLC,
July 2008.
- L. Yang, G. Song and R. L.
Jernigan. "Comparison of experimental and computed protein anisotropic
temperature factors",
in Proc. 2007 IEEE Int. Conf. Bioinfo. Biomed.
Workshops, pp 89-96, November 2007, Fremont, CA, USA.
[Link]
- L. Yang, G. Song and R. L. Jernigan. "Exploring
the dynamics of proteins from NMR structures and
validating normal modes", to be submitted.
- L. Yang, L. You, G. Song and R. L. Jernigan. "The
extent of improvement for protein B-factor prediction by combining structural
rigid body motions and internal flexibilities", in preparation.
- S. Avasarala, L. Yang, Y. Sun, A. W.
C. Leung, W. Y. Chan, W. T. Cheung and S. S. T. Lee. "A temporal study on the
histopathological, biochemical and molecular responses of CCl4-induced
hepatotoxicity in Cyp2e1-null mice" (2006), Toxicology, 228: 310-322.
[Link]
-
"How well can we understand large-scale protein
motions using elastic network modes?", The Joint Meeting of
the Biophysical Society 52nd Annual Meeting & 16th
International Biophysics Congress, February 2008, Long Beach, CA, USA.
-
"Comparison of experimental and computed protein anisotropic
temperature factors",
Computational Structural Bioinformatics Workshop (CSBW) on IEEE International Conference on Bioinformatics and Biomedicine (BIBM
2007), November 2007, San Jose, CA, USA.
-
"ENM: an R package for the
computational modelling and analysis of protein
dynamics using elastic network models", useR! 2007 - The R
User Conference, August 2007, Ames, IA, USA.
-
"Identification of essential
protein motions from principal component
analysis of multiple HIV-1 protease
structures and agreement with elastic network modes",
The 20th Annual Symposium
of The Protein Society & 20th
Anniversary Celebration, August 2006, San Diego, CA, USA.
-
"Identifying essential protein
motions from principal component analysis
of multiple HIV-1 protease
structures and agreement with elastic network modes",
The 32nd Steenbock Symposium - Dynamics of Proteins and
Macromolecular Assemblies, May 2006, Madison, WI, USA.
-
"Motion analysis of HIV-1
protease by anisotropic network
model and principal component analysis",
The 14th Growth Factors and
Signal Transduction Symposium - Integration of Structural and Functional
Genomics, September 2005, Ames, IA, USA.
-
"Motion analysis of HIV-1
protease by anisotropic network model and principal component analysis",
The 5th Annual Joint
Bioinformatics Workshop between UI and ISU, July 2005, Iowa City, IA,
USA.
-
"Identification of CYP2E1 dependent genes involved
in carbon tetrachloride (CCl4) and acetaminophen (APAP) induced
hepatotoxicity", The 13th International Symposium
on Microsomes and Drug Oxidations
(MDO2000), July 2000, Stresa, Italy.
-
"Differential display analysis
of peroxisome proliferator-activated receptor alpha (PPARĪ±) dependent genes involved in the
cellular fasting response", The 13th International Symposium on
Microsomes and Drug Oxidations (MDO2000), July 2000, Stresa, Italy.
- Elected Member of Sigma Xi
- Member of American Statistical Association (ASA)
- Member of American Association for the
Advancement of Science (AAAS)
- Member of Biophysical Society
- Reviewer for journal papers submitted to Proteins, Polymer, Cancer
Informatics, Journal of Biomolecular Structure and Dynamics and
Theoretical Chemistry Accounts and a NSF grant proposal
-
Guest Instructor of "Protein Dynamics",
Computational Biochemistry (BBMB541), Iowa State University, Fall 2007
-
Teaching Assistant, Survey of Biochemistry (BBMB301), Iowa State University, Spring 2006 & Fall 2006
- Teaching Assistant & Section Instructor of
"Transgenic
Technology", Molecular
Biotechnology (MBT4031),
Chinese University of Hong Kong, Spring 2000 & Spring 2001
-
Teaching Assistant, Environmental Science (ENS4251),
Chinese University of Hong Kong, Spring 2000
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