NATALYA A. BABENKO

Head of Department of Physiology of Ontogenesis

 

Kharkov National University

Institute  of Biology

pl.Svobody 4, Kharkov 61077

Ukraine

Phone + 380 572 457665

Fax +380 572 352923

 babenko@univer.kharkov.ua

 

Education

1992  Medical University, Kharkov,  Ukraine, Physiology. Hormonal and Dietic Factors of Regulation of Lipid Metabolism in Ontogenesis D.Sc

1985 Kharkov State University, Kharkov, Ukraine, Physiology. Phospholipids of Nuclear Structures in Ontogenesis. Ph.D

1974 Kharkov State University, Kharkov, Ukraine, Physiology M.S.

 

Post graduate training

1980 Gerontology School (Sochi, USSR)

1985 Molecular Biology School (Pushchino, USSR)

1990 Age and Evolutionary Physiology School (Leningrad, USSR)

1991 9th Summer School of the European Society of Membrane Science and Technology "Fundamentals  in  Membrane Science and Separation Processes" (Zvenigorod, Russia)

 

Research and Academic Positions

1974-1975 School Biology Lecturer (Kharkov, Ukraine)

1975-1976 Junior Research Associate of Medical Institute (Kharkov, Ukraine)

                       1977-1987 Junior Research Associate, Kharkov State University, Institute of Biology, Division of Molecular Biology &  Biochemistry of Ontogenesis, Kharkov, USSR.

                       1987-1990 Research Associate, Kharkov State University, Institute of Biology, Division of Molecular Biology & Biochemistry  of Ontogenesis, Kharkov, USSR.

                       1990-1993 Senior Research Associate, Kharkov State University, Institute of Biology, Division of Molecular Biology & Biochemistry of Ontogenesis, Kharkov, Ukraine.

1995 Visiting Professor, University of the Basque Country, Bilbao, Spain.

                       1993-1996 Leading Research Scientist, Kharkov State University, Institute of Biology, Division of Molecular Biology & Biochemistry of Ontogenesis, Kharkov, Ukraine.

1996 Head of Department of Physiology of Ontogenesis, Institute of Biology, Kharkov State University, Ukraine.

1996 Visiting Scientist,  University of the Basque Country, Bilbao, Spain.

 

Awards

·     The short-term Soros Humanitarian Foundation individual grant (1993)

·     The British Council individual grant (1994).

·     The Department of Education, Universities and Investigations individual grants, Spain (1995,1997).

·     Iowa State University and UNESCO individual grants, USA (1999, 2000).

·     The Award of the “Deutscher Akademischer Austauschdienst (DAAD)”, Bonn, Germany (1999).

 

Proffessional Membership

·     Academic Council Member for Animal and Human Physiology (Kharkov State University, 1995-2000)

·     Biology Institute Academic Council Member (Kharkov State University, 1994-2000)

·     Kharkov Physiology Society Board Secretary (Ukraine, 1986-2000)

·     Editorial Staff Member of the book:: Ontogenesis  Mechanisms and their Regulation (Kiev: Naukova Dumka, 1987)

·     Executive secretary of All-Ukrainian Symposium "Molecular and Functional Mechanisms of Ontogenesis" (Kharkov, Ukraine, 1987)

·     Kharkov Physiology Society Board Secretary (Ukraine, 1990-1995)

·     Vice-president of the International Symposium "Biological Mechanisms of Aging" (Kharkov, Ukraine, 1994, 1996, 1998, 2000)

 

     Selected Publications

     Kavok N.S., Krasilnikova O.A., Babenko N.A. Thyroxine signal transduction in liver cell involves phospholipase C and D activation. Genomic independent action of thyroid hormone ( in press).

 

Babenko N.A Kavok N.S. Effect of thyroid hormones on phosphatidylethanolamine metabolism in the liver cell nuclei (in press).

 

Tseng H.-C., Sakaguchi D.S., Fulton D.B., Babenko N.A., Graves D.J.The methylamine osmolyte, trimethylamine n-oxide (TMAO), stregthens cellular tubulin assembly in XR1 glial cells (in press).

 

Kavok N.S., Krasilnikova O.A., Sidorkina O.M., Babenko N.A. A rapid effect of thyroxine

on accumulation of diacylglycerols and on activation of protein kinase C in liver  cells.Biochemistry (Moscow) Engl.Tr. 65, P.1577-1583, 2000.

 

Krasilnikova O.A., Natarova Yu.A., Babenko N.A. Peculiarities of thyroxine action on sphingosine and phosphoinositide metabolism in rat liver in ontogenesis. Physiol. J. (Kiev), 46, P.26-32, 2000.

 

Babenko N.A, Natarova Yu.A. Role of thyroid hormones in regulation of sphingomyelin metabolism in the liver. Biochemistry (Moscow), Engl.Tr.64, P.1085-1089, 1999.

 

Babenko N.A., Ruiz-Larrea M.B., Martinez R., Martin C., Lacort M. Inhibition by estrogens of the oxidant-mediated mobilization of arachidonic acid in hepatocytes. J.Physiol. Biochem. 54(2), P.77-84, 1998. 

               

Ruiz-Larrea M.B., Martin C., Babenko N.A., Martinez R., Lacort M Diethylstilbestrol antagonizes the oxidant-induced transformations of membrane phospholipids. Biochemical Soc.Trans., 26. S224, 1998.

 

Babenko N.A., Lacort M., Ruiz-Larrea M.B. Phospholipase A2 mediates the oxidant-stimulated

arachidonic acid mobilization in rat liver hepatocytes. Toxicology Letters. 88 (Suppl.1), P.33-34, 1996.

 

Krasilnikova O.A., Babenko N.A. Role of thyroid hormones in regulation of phosphatidic acid, phosphatidylinositol, and polyphosphoinositide synthesis in liver cells. Biochemistry (Moscow), Engl. Tr. 61 P. 1008-1014, 1996.

 

Natarova Yu.A., Krasilnikova O.A., Babenko N.A. Effect of thyroxine on sphingomielin and phosphatidylcholine synthesis in rat hepatocytes. Ukr.Biochem J. 68, P.115-118, 1996.

 

Babenko N.A., Kavok N.S. Effect of thyroid hormones, phorbol esters and sphingosine on the incorporation of linoleic acid into lipids in the liver  of  white rats. Biochemistry (Moscow), Engl. Tr. 60 , P.1545-1550,1995.

 

Babenko N.A., Kavok N.S.  The role of thyroid hormones in the regulation of activity of phospholipases A1 and A2 in cells and in the liver cell nuclei of rats of various age. Biochemistry (Moscow), Engl. Tr. 59, P.1130-1139, 1994.

 

Babenko N.A., Filonenko N.S. Effects of thyroid hormones and diacylglycerols on sphyngomielin metabolism in  hepatocyte nuclei  of  rats of different age. Biochemistry (Moscow), Engl.Tr. 57. P. 242-246, 1992.

 

Babenko N.A. Regulation  of the sphingomyelinase and phospholipase C activities of liver cell plasma membranes from rats of different ages. Biochemistry (Moscow), Engl.,Tr., 56. P. 214-220, 1991.

 

Nikitin  V.N.,  Babenko N.A.      Age-specific differences in the  metabolism of nuclear phospholipid fatty acid components. In: Nuclear Structure and Function.  Proceeding of the Eleventh Nuclear  Workshop, 18-23 Sept 1989 (Ed. by J.R.Harris and I.B.Zbarsky) - New-York: Plenum publishing Corporation, p. 459-462, 1990.

 

Alesenko A.V.,  Babenko N.A.,  Pushcareva M.Y.,  Nikitin V.N. Comparison between  the level of sphingomielinase activity in the liver nuclei and in the brain. Byulliten experimentalnoi biologii i meditsini, (Experimental Biology and  Medicine Letters)9, p.287-289, 1989.