Functional Genomics of Plant Disease Defense
Positions are available immediately in the Iowa State University Center for Plant Responses to Enviromental Stresses under the direction of Drs. Roger Wise and Steve Whitham. The overall goals of the NSF-Plant Genome project “Functional Genomics of Plant Disease Defense Pathways” http://nsf.gov/awardsearch/showAward.do?AwardNumber=0500461 are to utilize functional genomics tools and resources available to barley, rice, and the model dicot Arabidopsis thaliana, to accelerate comparative analysis of disease defense pathways important in agriculture.
Candidates will work with a team responsible for molecular, genetic, and functional characterization of gene-specific sequences associated with and required for R-gene mediated resistance responses using barley powdery mildew as a model system. Approaches include utilization of the 22K Affymetrix Barley1 GeneChip to characterize the transcriptional networks regulated during powdery mildew induced programmed cell death and subsequent high-throughput reverse genetic systems in barley and Arabidopsis to functionally validate candidate genes in resistance pathways of both monocot and dicot plants. All of the above approaches will be facilitated by well-characterized, high-resolution, recombinant mapping populations, accelerated cell-death mutants, RNAi and TILLING silencing systems, BAC, cosmid, and cDNA library resources.
Funding is available up to three years. Salary is commensurate with experience. Ph.D. required in genetics, molecular biology, plant physiology, plant pathology or related field. Experience in bioinformatics/computational/statistical analysis, single-cell transcript profiling, RNAi mediated gene silencing, cell biology, and/or high-throughput gene mapping is desirable. Highly motivated individuals should send curriculum vitae, research interests, and reprints to:
|Dr. Roger Wise, USDA-ARS||Phone: 515-294-9756|
|Department of Plant Pathology||Fax: 515-294-9420|
|Iowa State Universityemail@example.com|
|Ames, IA, 50011-1020||http://wiselab.org/ ; http://plexdb.org/|
- Name, e-mail, address, phone, and fax no. of three references should be included -
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