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Department of Chemistry
Iowa State University

Publications

The publications on this site are being made available to the academic community for use in teaching and research. All copyrights remain intact.


2014

140.   H. Yao and M. Hong, ”°Conformation and Lipid Interaction of the Fusion Peptide of the Paramyxovirus PIV5 in Anionic and Negative-Curvature Membranes From Solid-State NMR”±, J. Am. Chem. Soc., 136, 2611-2624 (2014). pdf

2013

139.  Y. Yang, K.J. Fritzsching, and M. Hong, ”°Resonance Assignment of Disordered Proteins Using a Multi-Objective Non-Dominated Sorting Genetic Algorithm”±, J. Biomol. NMR, 57, 281-96 (2013). pdf

138. S.Y. Liao, K.J. Fritzsching, and M. Hong, ”°Secondary-Structure Analysis of the Full-Length M2 Protein of the Influenza A Virus From Solid-State NMR”±, Prot. Sci. 22, 1623-38 (2013). pdf

137.  T. Wang, Y.B. Park, M.A. Caporini, M. Rosay, D.J. Cosgrove and M. Hong, ”°Sensitivity-Enhanced Solid-State NMR Elucidation of Protein Binding to Cell Walls”±, Proc. Natl. Acad. Sci. USA, 110, 16444-9 (2013). pdf

136.  B. Kwon, A.J. Waring and M. Hong, ”°A 2H Solid-State NMR Study of Lipid Clustering by Cationic Antimicrobial and Cell-Penetrating Peptides in Model Bacterial Membranes”±, Biophys. J. 105, 2333-42 (2013). pdf

135.  R.L. Johnson, J.M. Anderson, B.H. Shanks, X. Fang, M. Hong, K. Schmidt-Rohr, ”°Spectrally edited 2D 13C-13C NMR spectra without diagonal ridge for characterizing 13C-enriched low-temperature carbon materials”±, J. Magn. Reson. 234C, 112-124 (2013). pdf

134.  J.K. Williams, D. Tietze, J. Wang, Y. Wu, W.F. DeGrado and M. Hong, ”°Drug-Induced Conformational and Dynamical Changes of the S31N Mutant of the Influenza M2 Proton Channel Investigated by Solid-State NMR”±, J. Am. Chem. Soc. 135, 9885-9897 (2013). pdf support_info

133.  K. J. Fritzsching, Y. Yang, K. Schmidt-Rohr, and Mei Hong, ”°Practical Use of Chemical Shift Databases for Protein Solid-State NMR: 2D Chemical Shift Maps and Amino-Acid Assignment with Secondary-Structure Information”±, J. Biomol. NMR, 56, 155-167 (2013). pdf

132.  T. Wang, H. Yao and M. Hong, ”°Determining the Depth of Insertion of Dynamically Invisible Membrane Peptides by Gel-Phase 1H Spin Diffusion Heteronuclear Correlation NMR”±, J. Biomol. NMR, 56, 139-148 (2013). pdf

131.  J. Williams, Y. Zhang, K. Schmidt-Rohr, and M. Hong, ”°Solid-state NMR investigation of the pH-dependent structure and dynamics of the gating residue of the influenza M2 proton channel”±, Biophys. J., 104, 1698-1708 (2013). New and Notable commentary on 1639-1640. pdf

130.  M. Hong and K. Schmidt-Rohr, ”°Magic-Angle-Spinning NMR Techniques for Measuring Long-Range Distances in Biological Macromolecules”±, Acct. Chem. Res, 46, 2154-63 (2013). pdf

129.  Su Y, Li S, and Hong M. ”°Cationic membrane peptides: atomic-level insight of structure-activity relationships from solid-state NMR”±, Amino Acids, 2013, 44, 821-833 (2013). pdf

128.  H.W. Yao, and M. Hong, ”°Membrane-Dependent Conformation, Dynamics, and Lipid Interactions of the Fusion Peptide of the Paramyxovirus PIV5 From Solid-State NMR”±, J. Mol. Biol, 425, 563-576 (2013). pdf
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2012

127.  T. Wang, O. Zabotina, and M. Hong, ”°Pectin-cellulose and protein-polysaccharide  interactions in Arabidopsis primary cell walls by 2D 13C Correlation NMR”±, Biochemistry, 51, 9846-9856 (2012).  pdf

126.  T. Wang, L. Widanapathirana, Y. Zhao and M. Hong, ”°Aggregation and Dynamics of Oligocholate Transporters in Phospholipid Bilayers Revealed by Solid-State NMR Spectroscopy”±, Langmuir, 28, 17071-17078 (2012). pdf

125.  K. Schmidt-Rohr, K. J. Fritzsching, S. Y. Liao, M. Hong, ”°Spectral Editing of Two-Dimensional Magic-Angle-Spinning Solid-State NMR Spectra for Protein Resonance Assignment and Structure Determination”±, J. Biomol. NMR., 54, 343-353 (2012). pdf

124.  M. Hong and W.F. DeGrado, ”°Structural Basis For Proton Conduction and Inhibition by the Influenza M2 Protein”±, Invited review, Prot. Sci, 21, 1620-1633 (2012). pdf

123.  S. Li, Y. Su, and M. Hong, ”°Intramolecular 1H-13C distance measurement in uniformly 13C, 15N labeled peptides by solid-state NMR”±, Solid State Nucl. Magn. Reson. 45-46, 51-58 (2012). pdf

122.  M. Hong, K. Fritzsching, and J. K. Williams, ”°Hydrogen-Bonding Partner of the Proton-Conducting Histidine in the Influenza M2 Proton Channel Revealed From 1H Chemical Shifts”±, J. Am. Chem. Soc. 134, 14753-14755 (2012). pdf

121.  Y. Su, F. Hu and M. Hong, ”°Paramagnetic Cu(II) For Probing Membrane Protein Structure and Function: Inhibition Mechanism of the Influenza M2 Proton Channel”±, J. Am. Chem. Soc. 134, 8693-8702 (2012). PMID: 22519936. pdf 

120.   M. Dick-Perez, T. Wang, A. Salazar, O. Zabotina, and M. Hong, ”°Multidimensional Solid-State NMR Studies of the Structure and Dynamics of Pectic Polysaccharides in Uniformly 13C-Labeled Arabidopsis Primary Cell Walls”±, Magn. Reson. Chem. 50, 539-550 (2012).  PMID: 22777793. pdf

119.   D. M Harris, K. Corbin, T. Wang, R. Gutierrez,  A.L. Bertolo, C. Petti, D.M. Smilgies, J. M. Estevez, D. Bonetta, B. Urbanowicz, D. Ehrhardt, C. R. Somerville, J. K.C. Rose, M. Hong, S. DeBolt, ”°Cellulose microfibril crystallinity is reduced by mutating C-terminal transmembrane region residues CESA1A903V and CESA3T942I of cellulose synthase”±, Proc. Natl. Acad. Sci. USA, 109, 4098-4103 (2012). PMID: 22375033.  pdf

118.   T. Wang, S.D. Cady, and M. Hong, ”°NMR Determination of Protein Partitioning into Membrane Domains with Different Curvatures and Application to the Influenza M2 Protein”±, Biophys. J. 102, 787-794 (2012). PMID: 22385849. pdf

117.   F. Hu, K. Schmidt-Rohr and M. Hong, ”°NMR Detection of pH-Dependent Histidine-Water Proton Exchange Reveals the Conduction Mechanism of a Transmembrane Proton Channel”±, J. Am. Chem. Soc. 134, 3703-3713 (2012). PMID: 21974716. pdf

116.  M. Hong, Y. Zhang and F. Hu, ”°Membrane protein structure and dynamics from NMR spectroscopy”±, Annual Review Phys. Chem. 63, 1-24 (2012). PMID: 22136620. pdf 

2011

115.  Y. Su and M. Hong, ”°Conformational disorder of membrane peptides investigated from solid-state NMR line widths and line shapes”±, J. Phys. Chem. 115, 10758-10767 (2011).  PMID: 21806038. pdf

114.   J. Wang, C. Ma, G. Fiorin, V. Carnevale, T. Wang, F. Hu, R. A. Lamb, M. L. Klein, L. H. Pinto, M. Hong, and W. F. DeGrado, ”°Molecular Dynamics Simulation Directed Rational Design of Inhibitors Targeting Drug-Resistant Mutants of Influenza A Virus M2”±, J. Am. Chem. Soc. 133, 12834-12841 (2011).  PMID: 21744829. pdf

113.   S.D. Cady, T. Wang, and M. Hong, ”°Membrane-Dependent Effects of a Cytoplasmic Helix on the Structure and Drug Binding of the Influenza M2 Protein”±, J. Am. Chem. Soc. 133, 11572-11579 (2011).  pdf

112.   Hong, M and Su, Y., ”°Structure and Dynamics of Cationic Membrane Peptides and Proteins: Insights from Solid-State NMR”±, Protein Sci., review, 20, 641-655 (2011). PMID: 21344534. pdf

111.   Y. Su, A.J. Waring, P. Ruchala, and M. Hong, ”°Structure of b-hairpin Antimicrobial Peptides in Lipopolysaccharide Membranes: Mechanism of Gram Selectivity Obtained from Solid-State Nuclear Magnetic Resonance”±, Biochemistry, 50, 2072-2083 (2011).  PMID: 21302955. pdf

110.   S.D. Cady, J. Wang, Yibing Wu, W.F. DeGrado, and M. Hong, ”°Specific binding of adamantane drugs and direction of their polar amines in the pore of the influenza M2 transmembrane domain in lipid bilayers and dodecylphosphocholine micelles determined by NMR spectroscopy”±, J. Am. Chem. Soc. 133, 4274-4284 (2011) pdf

109.   M. Dick-Perez, Y. Zhang, J. Hayes, A. Salazar, O.A. Zabotina and M. Hong, ”°Structure and Interactions of Plant Cell-Wall Polysaccharides by 2D and 3D Magic-Angle-Spinning Solid-State NMR”±, Biochemistry, 50, 989-1000 (2011). PMID: 21204530. pdf

108.   S. Li and M. Hong, ”°Protonation, Tautomerization and Rotameric Structure of Histidine: A Comprehensive Study through High Resolution Solid-state NMR”±, J. Am. Chem. Soc. 133, 1534-1544 (2011). PMID: 21207964. pdf

107.   F. Hu, W. Luo, S.D. Cady and M. Hong, ”°Conformational Plasticity of the Influenza A M2 Transmembrane Peptide in Lipid Bilayers Under Varying pH, Drug Binding and Membrane Thickness”±, Biochim. Biophys. Acta, 1808, 415-423 (2011). PMID: 20883664. pdf

2010

106.  Y. Zhang and M. Hong, ”°Membrane-bound structure and topology of a human alpha-defensin indicates dimer pore as the mechanism of antimicrobial activity”±, Biochemistry, 49, 9770-9782 (2010). pdf

105.   F. Hu, W. Luo, and M. Hong, ”°Mechanisms of proton conduction and gating by influenza M2 proton channels from solid-state NMR”±, Science, 330, 505-508 (2010). full text

104.   Y. Su, A.J. Waring, P. Ruchala, and M. Hong, ”°Membrane-bound dynamic structure of an Arginine-rich cell-penetrating peptide, the protein transduction domain of HIV TAT, from solid-state NMR”±, Biochemistry, 49, 6009-6020 (2010). DOI: 10.1021/bi100642n. PMCID: PMC2925115. pdf

103.   Y. Su, W.F. DeGrado and M. Hong, ”°Orientation, dynamics and lipid interaction of an antimicrobial arylamide in lipid bilayers investigated by 19F and 31P solid-state NMR”±, J. Am. Chem. Soc. 132, 9197-9205 (2010). PMCID: PMC2904348. pdf

102.   T. Doherty*, Y. Su* (* indicates equal contribution) and M. Hong, ”°High-Resolution Orientation and Depth of Insertion of the Voltage-Sensing S4 Helix of a Potassium Channel in Lipid Bilayers”±, J. Mol. Biol. 401, 642-652 (2010). PMCID: PMC2918711.pdf

101.   S. Li, Y. Su, W. Luo, M. Hong, ”°Water-protein interactions of an arginine-rich membrane peptide in lipid bilayers investigated by solid-state nuclear magnetic resonance spectroscopy”±. J. Phys. Chem. B, 114, 4063-4069. PMCID: PMC2853767. pdf

100.    W. Luo and M. Hong, ”°Conformational Changes of an Ion Channel Detected Through Water-Protein Interactions Using Solid-State NMR”±, J. Am. Chem. Soc. 132, 2378-2384 (2010). PMCID: PMC2829254. pdf support_info

99.    S. D. Cady, K. Schmidt-Rohr, J. Wang, C.S. Soto, W. F. DeGrado, and M. Hong, ”°Structure of the amantadine binding site of influenza M2 proton channels In lipid bilayers”±, Nature, 463, 689-692 (2010). DOI: 10.1038/nature08722. PMCID: PMC2818718. pdf support_info

98.    S. Li, Y. Zhang, and M. Hong, ”°3D 13C-13C-13C Correlation NMR for De Novo Distance Determination of Solid Proteins and Application to a Human Alpha Defensin”±, J. Magn. Reson. 202, 203-210 (2010). PMCID: PMC2819753. pdf

97.    Y. Zhang, T. Doherty, J. Li, W. Lu, C. Barinka, J. Lubkowski and M. Hong, ”°Resonance Assignment and Three-Dimensional Structure Determination of a Human Alpha-Defensin, HNP-1, by Solid-State NMR”±, J. Mol. Biol., 397, 408-422 (2010). PMCID: PMC2873975. pdf

2009

96.     S.D. Cady, W. Luo, F. Hu, and M. Hong, ”°Structure and function of the influenza M2 proton channel”±, Current Topic, Biochemistry, 48, 7356-7364 (2009). DOI: 10.1021/bi9008837. pdf

95.    S. D. Cady and M. Hong, ”°Effects of Amantadine Binding on the Dynamics of Bilayer-Bound Influenza A M2 Transmembrane Peptide Studied by NMR Relaxation”±, J. Biomol. NMR, 45, 185-196. (2009). DOI 10.1007/s10858-009-9352-9. pdf

94.    T. Doherty and M. Hong, ”°High-Resolution Solid-State NMR of Anisotropically Mobile Molecules Under Very Low Power 1H Decoupling and Moderate Magic-Angle Spinning”±, J. Magn. Reson. 199, 225-232 (2009). DOI:10.1016/j.jmr.2009.05.006 pdf

93.    M. Hong, T.V. Mishanina and S.D. Cady, ”°Accurate Measurement of Methyl 13C Chemical Shifts by Solid-State NMR for the Determination of Protein Sidechain Conformation: the Influenza A M2 Transmembrane Peptide as an Example”±, J. Am. Chem. Soc. 131, 7806-7816 (2009). DOI: 10.1021/ja901550q. pdf

92.    Y. Su and M. Hong, ”°Roles of arginine and lysine residues in the translocation of a cell-penetrating peptide from 13C, 31P, and 19F solid-state NMR”±, Biochemistry, 48, 4587-4595 (2009). DOI:10.1021/bi900080d. pdf support_info

91.     J. Wang, S.D. Cady, V. Balannik, L.H. Pinto, W.F. DeGrado, and M. Hong, ”°Discovery of Spiro-piperidine inhibitors and their modulation of the dynamics of the M2 proton channel from influenza A Virus”±, J. Am. Chem. Soc. 131, 8066-8076 (2009). pdf

90.    W. Luo, S.D. Cady, and M. Hong, ”°Immobilization of the Influenza A M2 Transmembrane Peptide in Viral-Envelope Mimetic Lipid Membranes Detected by Solid-State NMR Spectroscopy”±, Biochemistry, 48, 6361-6368 (2009). DOI: 10.1021/bi900716s. pdf  support_info

89.    M. Tang. and M. Hong. ”°Structure and Mechanism of Beta-Hairpin Antimicrobial Peptides in Lipid Bilayers from Solid-State NMR Spectroscopy”±, Mol. Biosys, 5, 317-322 (2009).  DOI: 10.1039/b820398a. pdf

88.    S. D. Cady, T.V. Mishanina and M. Hong, ”°Structure of Amantadine-Bound M2 Transmembrane Peptide of Influenza A in Lipid Bilayers from Magic-Angle-Spinning Solid-State NMR: the Role of Ser31 in Amantadine Binding, J. Mol. Biol. 385, 1127-1141 (2009). doi: 10.1016/j.jmb.2008.11.022. pdf

””

87.    M. Tang, A.J. Waring and M. Hong, ”°Effects of Arginine Density on the Membrane-Bound Structure of a Cationic Antimicrobial Peptide from Solid-State NMR”±, Biochim. Biophys. Acta, 1788, 514-521 (2009). doi:10.1016/j.bbamem.2008.10.027. pdf

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86.    T. Doherty and M. Hong, ”°2D 1H-31P Solid-State NMR Studies of the Dependence of Inter-bilayer Water Dynamics on Lipid Headgroup Structure and Membrane Peptides”±, J. Magn. Reson., 196, 39-47 (2009). doi:10.1016/j.jmr.2008.10.001. pdf

2008

85.    Y. Su, R. Mani, T. Doherty, A. J. Waring and M. Hong, "Reversible Sheet - Turn Conformational Change of a Cell-Penetrating Peptide in Lipid Bilayers Studied by Solid-State NMR", J. Mol. Biol. 381,1133 -1144 (2008). pdf support_info

””

84.    Y. Su, R. Mani, and M. Hong, "Asymmetric Insertion of Membrane Proteins in Lipid Bilayers by Solid-State NMR Paramagnetic Relaxation Enhancement: a Cell-Penetrating Peptide Example", J. Am. Chem. Soc., 130, 8856-8864 (2008). pdf support_info

””

83.    M. Tang, A. J. Waring, and M. Hong, "Arginine Dynamics in a Membrane-Bound Cationic Beta-Hairpin Peptide from Solid-State NMR", ChemBioChem, 9, 1487-1492 (2008). pdf

””

82.    M. Tang, A. J. Waring, R. I. Lehrer and M. Hong, "Effects of Guanidinium-Phosphate Hydrogen Bonding on the Membrane-Bound Structure and Activity of an Arginine-Rich Membrane Peptide from Solid State NMR",  Angew. Chem. Int. Ed. Engl., 47, 3202-3205 (2008). pdf support_info

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81.    S.D. Cady and M. Hong, "Simultaneous extraction of multiple orientational constraints of membrane proteins by 13C-detected N-H dipolar couplings under magic angle spinning", J. Magn. Reson., 191, 219-225 (2008). pdf

 

80.    S.D. Cady and M. Hong, "Amantadine-Induced Conformational and Dynamical Changes of the Influenza M2 Transmembrane Proton Channel", Proc. Natl. Acad. Sci. U.S.A.,105, 1483-1488 (2008). pdf support_info

 

79.    T. Doherty, A.J. Waring and M. Hong, "Dynamic Structure of Disulfide-Removed Linear Analogs of Tachyplesin-I in the Lipid Bilayer from Solid-State NMR", Biochemistry, 47, 1105-1116 (2008). pdf support_info

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 2007

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78.    R. Mani, A.J. Waring, and M. Hong, "Conformation, Dynamics and Insertion of a Non-Cysteine-Containing Protegrin-1 Analog in Lipid Membranes from Solid-State NMR', ChemBioChem. 8, 1877-1884 (2007). pdf

 

77.    M. Hong, "Structure, Topology, and Dynamics of Membrane Peptides and Proteins from Solid-State NMR Spectroscopy", J. Phys. Chem. B. feature article, 111, 10340-10351 (2007). pdf

 

76.    W. Luo, R. Mani and M. Hong, "Sidechain Conformation and Gating of the M2 Transmembrane Peptide Proton Channel of Influenza A Virus from Solid-State NMR", J. Phys. Chem. B. 111, 10825-10832 (2007). pdf

 

75.    S.D. Cady, C. Goodman, C. Tatko, W.F. DeGrado, and M. Hong, "Determining the Orientation of Uniaxially Rotating Membrane Proteins Using Unoriented Samples: a 2H, 13C, and 15N Solid-State NMR Investigation of the Dynamics and Orientation of a Transmembrane Helical Bundle", J. Am. Chem. Soc. 129, 5719-5729 (2007). pdf

 

74.    M. Tang, A.J. Waring and M. Hong, "Trehalose-Protected Lipid Bilayers for Determining Membrane Protein Insertion and Topology", J. Magn. Reson. 184, 222-227 (2007). pdf

 

73     M. Tang, A. J. Waring and M. Hong, "Phosphate-Mediated Arginine Insertion Into Lipid Membranes and Pore Formation by a Cationic Membrane Peptide from Solid-State NMR", J. Am. Chem. Soc. 129, 11438-11446 (2007). pdf

 

 2006

””

72.    M. Hong and T. Doherty, "Orientation Determination of Membrane-Disruptive Proteins Using Powder Samples and Rotational Diffusion: A Simple Solid-State NMR Approach", Chem. Phys. Lett. 432, 296-300 (2006).pdf

 

71.    M. Hong, "Oligomeric structure, dynamics, and orientation, of membrane proteins from solid-state NMR", Structure, review, 14, 1731-1740 (2006). pdf

 

70.    T. Doherty, A. J. Waring and M. Hong, "Membrane-bound conformation and topology of Tachyplesin-1 by solid-state NMR spectroscopy", Biochemistry, 45, 13323-13330 (2006). pdf

 

69.    R. Mani, S.D. Cady, M. Tang, A.J. Waring, R.I. Lehrer, and M. Hong, "Membrane-dependent oligomeric structure and pore formation of a ¦Ā-hairpin antimicrobial peptide in lipid bilayers from solid-state NMR", Proc. Natl. Acad. Sci. U.S.A., 103, 16242-16247 (2006). pdf

 

68.    R. Mani, M. Tang, X. Wu, J. J. Buffy, A. J. Waring, M. A. Sherman, and M. Hong, "Membrane-Bound Dimer Structure of a ¦Ā-Hairpin Antimicrobial Peptide from Rotational-Echo Double-Resonance Solid-State NMR", Biochemistry, 45, 8341-8349 (2006). pdf

 

67.    W. Luo and M. Hong, "Determination of the Oligomeric Number and Intermolecular Distances of Membrane Protein Assemblies by Anisotropic 1H-Driven Spin Diffusion NMR", J. Am. Chem. Soc. 128, 7242-7251 (2006). pdf

 

66.   T. Doherty, A. Waring, and M. Hong, "Peptide-Lipid Interactions of the ¦Ā-Hairpin Antimicrobial Peptide Tachyplesin and its Linear Derivatives from Solid-State NMR", Biochim. Biophys. Acta, 1758, 1285-1291 (2006). pdf

 

65.    M. Hong, "Solid-State NMR Studies of the Structure and Dynamics of Disordered and Membrane-Bound Peptides and Proteins",  Acct. Chem. Res., 39, 176-183 (2006). pdf

 

64.    X.L. Yao and M. Hong, "Effects of Anionic Lipid and Ion Concentrations on the Topology and Segmental Mobility of Colicin Ia Channel Domain From Solid-State NMR",  Biochemistry, 45, 289-295 (2006). pdf

 

63.    W. Luo and M. Hong, "1D Sensitivity-Enhanced 1H Spin Diffusion Experiment for Determining Membrane Protein Topology",  Solid State Nuc. Magn. Reson., 29, 163-169 (2006). pdf

 

62.    M. Tang, A.J. Waring, R.I. Lehrer, and M. Hong, "Orientation of a ¦Ā-hairpin Antimicrobial Peptide in Lipid Bilayers from 2D Dipolar Chemical-Shift Correlation NMR",  Biophys. J., 90, 3616-3624 (2006). pdf

 

 

2005

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61.    P.A.B. Marasinghe, J.J. Buffy, K. Schmidt-Rohr and M. Hong, "Membrane Curvature Change Induced by an Antimicrobial Peptide Detected by 31P Exchange NMR", J. Phys. Chem. B, 109, 22036-44 (2005). pdf

 

60.    M. Tang, A.J. Waring, and M. Hong, "Intermolecular Packing and Alignment of a ¦Ā-Hairpin Peptide from 2D Solid-State NMR",  J. Am. Chem. Soc., 127, 13919-13927 (2005). pdf

 

59.    R. Mani, A.J. Waring, R.I. Lehrer, and M. Hong, "Membrane-Disruptive Abilities of ¦Ā-Hairpin Antimicrobial Peptides Correlate with Conformation and Activity: A 31P and 1H NMR Study", Biochim. Biophys. Acta, 1716, 11-18 (2005). pdf

 

58.    S. Wi, H. Sun, E. Oldfield and M. Hong, "Solid-State NMR and Quantum Chemical Investigations of 13C¦Į Shielding Tensor Magnitudes and Orientations in Peptides: Determining ¦Õ and ¦× Torsion Angles", J. Am. Chem. Soc., 127, 6451-8 (2005). pdf

 

57.    W. Luo, X.L. Yao and M. Hong, "Evidence of Large Structure Rearrangement of Colicin Ia Channel Domain Due to Membrane Binding from 2D 13C Spin Diffusion NMR", J. Am. Chem. Soc., 127, 6402-8 (2005). pdf

 

56.    J.J. Buffy, A.J. Waring, and M. Hong, "Determination of Peptide Oligomerization in Lipid Bilayers Using 19F Spin Diffusion NMR", J. Am. Chem. Soc., 127, 4477-4483 (2005). pdf

 

55.    M. Hong and S. Wi, "Torsion Angle Determination in Biological Solids by Solid-State NMR", chapter 4, NMR spectroscopy of Biological Solids, CRC Press, Boca Raton, 2005.

 

 

2004

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54.    R. Mani, J.J. Buffy, A.J. Waring, R.I. Lehrer, and M. Hong, "Solid-State NMR Investigation of the Selective Disruption of Lipid Membranes by Protegrin-1",  Biochemistry, 43, 13839-48 (2004). pdf

 

53.    S. Wi N. Sinha and M. Hong, "Long-range distances by heteronuclear detected 19F-1H rotational-echo double-resonance NMR", J. Am. Chem. Soc. 126, 12754-5 (2004). pdf

 

52.    N. Sinha, K. Schmidt-Rohr and M. Hong, "Compensation for Pulse Imperfections in Rotational-Echo Double-Resonance NMR by Composite Pulses and EXORCYCLE", J. Magn. Reson. 168, 358-65 (2004). pdf

 

51.    J.J. Buffy, M.J. McCormick, S. Wi, A. Waring, R.I. Lehrer, and M. Hong, "Selective Perturbation of Lipid Membranes by the Cyclic Antimicrobial Peptide RTD-1 Investigated by Solid-State NMR", Biochemistry, 43, 9800-9812 (2004). pdf

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50.    A.T. Petkova, M. Baldus, M. Belenky, M. Hong, R.G. Griffin, J. Herzfeld, "Backbone and side chain assignment strategies for multiply labeled membrane peptides and proteins in the solid state", J. Magn. Reson. 160: 1-12 (2003). pdf

 

49.    G.J. Gallagher, M. Hong, L.K. Thompson, 'Solid-state NMR spin diffusion for measurement of membrane-bound peptide structure: gramicidin A", Biochemistry, 43, 7899-7906 (2004). pdf

 

48.    X.L. Yao and M. Hong, "Structural Distribution in an Elastin-Mimetic Peptide by Magic-Angle Spinning Solid-State NMR Spectroscopy", J. Am. Chem. Soc., 126, 4199-4210 (2004). pdf

 

47.    X.L. Yao, R.A. McMillian, V.P. Conticello, and M. Hong, "Investigation of the Dynamics of an Elastin-Mimetic Polypeptide Using Solid-State NMR",  Magn. Reson. Chem. 42, 267-275 (2004). pdf

 

 

2003

””

46.    N. Sinha and M. Hong, "1H Rotational-Echo Double-Resonance NMR For Torsion Angle Determination in Peptides", Chem. Phys. Lett. 380, 742-748 (2003). pdf

 

45.    J. Buffy, A.J. Waring, R. I. Lehrer, and M. Hong, "Immobilization and Aggregation of Antimicrobial Peptide Protegrin in Lipid Bilayers by Solid-State NMR",  Biochemistry, 42, 13725-34 (2003). pdf

 

44.    K. Schmidt-Rohr and M. Hong, "Measurements of Carbon to Amide-Proton Distances by C-H Dipolar Recoupling with 15N NMR Detection", J. Am. Chem. Soc. 125, 5648-5649 (2003). pdf

 

43.    J. Buffy, T. Hong, A. Waring, R. I. Lehrer, and M. Hong, "Solid-State NMR Investigation of the Depth of Insertion of PG-1 in DLPC Using Paramagnetic Mn2+", Biophys. J. 85, 2363-2373 (2003). pdf

 

42.    M. Hong and X.L. Yao, "Homonuclear decoupled 13C chemical shift anisotropy in multiply labeled peptides by selective-pulse solid-state NMR", J. Magn. Reson. 160, 114-119 (2003). pdf

 

41.    M. Hong, D. Isailovic, R.A. McMillan, and V.P. Conticello, "Solid-state NMR chemical shift constraints for the structure of an elastin-mimetic protein",  Biopolymers, 70, 158-168, (2003). pdf

 

 

2002

””

40.    X.L. Yao, S. Yamaguchi and M. Hong, "C¦Į Chemical Shift Tensors in Helical Peptides by Dipolar-Modulated Chemical Shift Recoupling NMR", J. Biomol. NMR, 24, 51-62 (2002). pdf

 

39.    S. Yamaguchi, A. Waring, T. Hong, R. Lehrer and M. Hong, "Solid-state NMR Investigations of Peptide-Lipid Interaction and Orientation of a ¦Ā-sheet antimicrobial peptide, Protegrin", Biochemistry, 41, 9852-9862 (2002). pdf

 

38.    M. Hong, X.L. Yao, K. Jakes and D. Huster, "Investigation of Molecular Motions by Magic-Angle Cross-Polarization NMR Spectroscopy", J. Phys. Chem., 106, 7355-7364 (2002). pdf

 

37.    X.L. Yao and M. Hong, "Determination of C¦Į Chemical Shift Tensor Orientation in Peptides By Dipolar-Modulated Chemical Shift Recoupling Solid-State NMR",  J. Am. Chem. Soc., 124, 2730-2738 (2002). pdf

 

36.    D. Huster, X.L. Yao and M. Hong, "Membrane Protein Topology Probed by 1H Spin Diffusion from Lipids Using Solid-State NMR Spectroscopy", J. Am. Chem. Soc. 124, 874-883 (2002). pdf

 

35.    M. Hong*, R.A. McMillan, and V.P. Conticello, "Measurement of Conformational Constraints in an Elastin-Mimetic Protein by Residue-Pair Selected Solid-State NMR", J. Biomol. NMR, 22, 175-179 (2002). pdf

 

34.    S. Yamaguchi and M. Hong, "Orientation of Membrane Peptides by 1H-Detected Deuterium NMR",  J. Magn. Reson. 155, 244-250 (2002). pdf

 

33.    D. Huster, X.L. Yao, K. Jakes, and M. Hong, "Conformational changes of colicin Ia channel-forming domain upon membrane binding: a solid-state NMR study",  Biochim. Biophys. Acta, 1561, 159-170 (2002). pdf

 

 

2001

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32.    S. B. Kennedy, E. de Azevedo, W. A. Petka, D.A. Tirrell, T.P. Russell, and M. Hong, "Dynamic Structure of a Protein Hydrogel: A Solid-State NMR Study", Macromolecules 34, 8675-8685 (2001). pdf

 

31.    S. Yamaguchi, D. Huster, A. Waring, R.I. Lehrer, W. Kearney, B.F. Tack, and M. Hong, "Orientation and Dynamics of an Antimicrobial Peptide in the Lipid Bilayer by Solid-State NMR", Biophys. J., 81, 2203-2214 (2001). pdf

 

30.    X.L. Yao and M. Hong, "Dipolar Filtered 1H-13C Heteronuclear Correlation Spectroscopy For Resonance Assignment of Proteins", J. Biomol. NMR, 20, 263-274 (2001). pdf

 

29.    X. L. Yao, K. Schmidt-Rohr, and M. Hong, "Medium- and Long-Distance 1H-13C Heteronuclear Correlation NMR in Solids", J. Magn. Reson. 149, 139-143 (2001). pdf

 

28.    K. Schmidt-Rohr, K. Saalwachter, S. Liu, and M. Hong, "High-Sensitivity 2H-NMR in Solids by 1H Detection", J. Am. Chem. Soc. 123, 7168-7169 (2001). pdf

 

27.    D. Huster, L.S. Xiao, and M. Hong, "Solid-State NMR Investigation of the Dynamics of Colicin Ia Channel-Forming Domain", Biochemistry, 40, 7662-7674 (2001). pdf

 

26.    M. Hong and S. Yamaguchi, "Sensitivity-Enhanced 15N Static NMR in Solids by 1H Indirect Detection", J. Magn. Reson. 150, 43-48 (2001). pdf

 

 

1999-2000

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25.   D. Huster, S. Yamaguchi, and M. Hong, "Efficient ¦Ā-Sheet Identification in Proteins by Solid-State NMR spectroscopy", J. Am. Chem. Soc., 122, 11320-11327 (2000). pdf

 

24.   M. Hong, "Solid-State NMR Determination of 13C¦Į Chemical Shift Anisotropy for the Identification of Protein Secondary Structure", J. Am. Chem. Soc. 122, 3762-3770 (2000). pdf

 

23.   C. M. Rienstra, M. Hohwy, M. Hong and R. G. Griffin, "1D and 3D 15N-13C-13C NMR chemical shift correlation spectroscopy of solids: assignment of MAS spectra of peptides", J. Am. Chem. Soc., 122, 10979-10990 (2000). pdf

 

22.    D. J. Harris, T. J. Bonagamba, M. Hong and K. Schmidt-Rohr, "Conformation of Poly(ethylene oxide)-Hydroxybenzene Molecular Complexes Studied by Solid-state NMR",  Macromolecules 33, 3375-3381 (2000). pdf

 

21.    E. R. deAzevedo, S. B. Kennedy and M. Hong, "Determination of Slow Motions in Extensively Isotopically Labeled Proteins by Magic-Angle-Spinning 13C-Detected 15N Exchange NMR", Chem. Phys. Lett. 321, 43-48 (2000). pdf

 

20.    M. Hong, "Resonance Assignment of 13C, 15N Labeled Proteins by Two- and Three-Dimensional Magic-Angle-Spinning NMR", J. Biomol. NMR 15, 1-14 (1999). pdf

 

19.    M. Hong and K. Jakes, "Selective and Extensive 13C Labeling of a Membrane Protein for Solid-State NMR Investigation", J. Biomol. NMR 14, 71-74 (1999). pdf

 

18.    M. Hong, "Determination of Multiple ¦Õ Torsion Angles in Solid Proteins by Selective and Extensive 13C Labeling and Two-Dimensional Solid-State NMR", J. Magn. Reson. 139, 389-401 (1999). pdf

 

17.    D. Sandstrom, M. Hong and K. Schmidt-Rohr, "Identification and Mobility of Deuterated Sites in Peptides and Proteins by 2H-13C Correlation in Solid-State NMR", Chem. Phys. Lett. 300, 213-220 (1999). pdf

 

16.    M. Hong, "Solid-State Dipolar INADEQUATE NMR Spectroscopy with a Large Double-Quantum Spectral Width", J. Magn. Reson. 136, 86-91 (1999). pdf

 

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1997-1998

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15.     A.T. Petkova, M. Baldus, M. Belenky, M. Hong, R.G. Griffin ,J. Herzfeld, ”°Backbone and side chain assignment strategies for multiply labeled membrane peptides and proteins in the solid state”±, J Magn Reson. 160, 1-12 (2003). pdf

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14.    M. Hong, J.D. Gross, W. Hu and R.G. Griffin, "Determination of the Peptide Torsion Angle ¦µ by 15N Chemical Shift and 13C¦Į-1H¦Į Dipolar Tensor Correlation in Solid-State MAS NMR", J. Magn. Reson. 135, 169-177 (1998). pdf

 

13.    M. Hong and R.G. Griffin, "Resonance Assignments for Solid Peptides by Dipolar-Mediated 13C/15N Correlation Solid-State NMR", J. Am. Chem. Soc. 120, 7113-7114 (1998). pdf

 

12.    P.R. Costa, J.D. Gross, M. Hong and R.G. Griffin, "A NCCN 2Q-HLF Experiment for ¦· Torsion Angle Measurements in Peptides", Chem. Phys. Lett. 280, 95-103 (1997). pdf

 

11.    M. Hong, J.D. Gross, C.M. Rienstra, R.G. Griffin, K.K. Kumashiro and K. Schmidt-Rohr, "Coupling Amplification in 2D MAS NMR and its Application to Torsion Angle Determination in Peptides", J. Magn. Reson. 129, 85-92 (1997). pdf

 

10.    M. Hong, J.D. Gross and R.G. Griffin, "Site-resolved Determination of Peptide Torsion Angle ¦µ from the Relative Orientations of Backbone N-H and C-H Bonds by Solid-State NMR", J. Phys. Chem. 101, 5869-5874 (1997).pdf

 

 

1994-1996

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 9.     S. Caldarelli, M. Hong, L. Emsley and A. Pines, "Measurement of Carbon-Proton Dipolar Coupling in Liquid Crystals by Local Dipolar Field NMR Spectroscopy", J. Phys. Chem. 100, 18696-18701 (1996). pdf

 

 8.     M. Hong, A. Pines and S. Caldarelli, "Measurement and Assignment of Long-Range C-H Dipolar Couplings in Liquid Crystals by Two-Dimensional NMR Spectroscopy', J. Phys. Chem. 100, 14815-14822 (1996). pdf

 

 7.     M. Hong and K. Schmidt-Rohr, "Conformational Constraints on the Headgroup and sn-2 Chain of Bilayer DMPC from NMR Dipolar Couplings",  Biochemistry 35, 8335-8341 (1996). pdf

 

 6.     K. Schmidt-Rohr and M. Hong, "Information on Bond Orientation Distributions in Lipids and Liquid Crystals from Segmental Order Parameters", J. Phys. Chem. 100, 3861-3866 (1996). pdf

 

 5.     M. Hong, K. Schmidt-Rohr and D. Nanz, "Study of Phospholipid Structure by 1H, 13C, and 31P Dipolar Couplings from Two-Dimensional NMR",  Biophys. J. 69, 1939-1950 (1995).

 

 4.     M. Hong and K. Schmidt-Rohr, "DISTINCT NMR for Sign Determination of C-H Dipolar Couplings in Liquid-Crystalline Lipids", J. Magn. Reson. B 109, 284-290 (1995).

 

 3.     M. Hong, K. Schmidt-Rohr and A. Pines, "NMR Measurement of Signs and Sizes of C-H Dipolar Couplings in Lecithin",  J. Am. Chem. Soc. 117, 3310-3311 (1995).

 

 2.     D. Nanz, M. Ernst, M. Hong, M.A. Ziegeweid, K. Schmidt-Rohr and A. Pines, "Low-Power Decoupling with Windowless Multiple-Pulse Sequences for High-Resolution Spectra of Orientationally Ordered Samples", J. Magn. Reson. A 113,169-176 (1995).

 

 1.     Y.K. Lee, L. Emsley, R.G. Larsen, K. Schmidt-Rohr, M. Hong, L. Frydman, G.C. Chingas and A. Pines, "Three-Dimensional Variable-Angle Nuclear Magnetic Resonance Exchange Spectroscopy without Rotor Axis Hopping",  J. Chem. Phys. 101 (3), 1852-1864 (1994).

 

 


Professor Mei Hong
Department of Chemistry
0219 Hach Hall, Iowa State University
Ames, Iowa 50011-3111
Tel: 515-294-3521
Fax: 515-294-0105
Email: mhong@iastate.edu

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