BCB 444/544
Introduction to Bioinformatics
Bioinformatics and Computational Biology

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Required Reading

• HW 4 paper: Ginalski et al.(2005) Practical Lessons from Protein Structure Prediction, Nucleic Acids Res.33:1874-91 PDF
• 544 students only: http://www.nature.com/nature/journal/v443/n7108/abs/nature05113.html (PDF)

• Basic Biology for lecture on 8/24/07 (Friday)

http://www.ornl.gov/sci/techresources/Human_Genome/publicat/primer2001/index.shtml

      You don't need the PPTs - just the PDF!

• Eddy, What is dynamic programming? (PDF)
• Eddy, What is a hidden Markov model? (PDF)
• BCB 544 Extra Required Reading Assignment: Pollard KS, Salama SR, Lambert N, Lambot MA, Coppens S, Pedersen JS, Katzman S, King B, Onodera C, Siepel A, Kern AD, Dehay C, Igel H, Ares M Jr, Vanderhaeghen P, Haussler D. (2006) An RNA gene expressed during cortical development evolved rapidly in humans. Nature 443: 167-172. PDF

Assigned Websites

• Literature Resources for Bioinformatics for Lab1 on 8/23/07 (Thursday)

http://www.public.iastate.edu/~adinkelm/Bioinformatics_Resources.htm

Optional Reading & Websites

· Brendel et al (2004) Bioinformatics 20: 1157 paper on gene prediction

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