Statistics 516X Lecture Notes

Lecture Notes

1. Introduction to Statistical Design and Analysis of Microarray Experiments     PowerPoint     PDF
2. Some Basic Biology Related to Microarray Technology     PowerPoint     PDF
3. The Basics of cDNA Microarray Technology     PowerPoint     PDF
4. The Basics of Oligonucleotide Microarray Technology     PowerPoint     PDF
5. The Basics of Microarray Image Processing     PowerPoint     PDF
6. Normalization Methods for Two-Color Microarray Data     PowerPoint     PDF
7. Normalization and Construction of Expression Measures for Affymetrix GeneChip Data     PowerPoint     PDF
8. Introduction to Experimental Design     PowerPoint     PDF    
9. Split Plot Experimental Designs     PowerPoint     PDF
10. Incomplete Block Experimental Designs     PowerPoint     PDF
11. Latin Square Experimental Designs     PowerPoint     PDF
12. Introduction to Mixed Linear Models     PowerPoint     PDF
13. Choosing between Competing Experimental Designs     PowerPoint     PDF
14. Multiple Testing Methods for the Analysis of Microarray Data     PowerPoint     PDF
15. Mixture Modeling of the p-value Distribution     PowerPoint     PDF
16. Introduction to Randomization Tests     PowerPoint     PDF
17. Significance Analysis of Microarrays (SAM)     PowerPoint     PDF
18. Estimation of Gene-Specific Variances     PowerPoint     PDF
19. Parametric Empirical Bayes Methods for Microarrays     PowerPoint     PDF
20. A Hidden Markov Model for Microarray Time Course Data in Multiple Biological Conditions     PowerPoint     PDF
21. Mixture modeling of the distribution of p-values from t-tests     PowerPoint     PDF
22. Cluster Analysis of Microarray Data     PowerPoint     PDF
23. Identifying Differentially Expressed Gene Categories     PowerPoint     PDF
24. Discussion of Hidden Markov Models for Microarray Time Course Data in Multiple Biological Conditions     PowerPoint     PDF
25. Rhonda DeCook's Presentation on eQTL Analysis     PowerPoint     PDF