Tim's CV

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Curriculum Vitae

Tim A. Day
Assistant Professor
Department of Biomedical Sciences
Iowa State University, Ames, IA 50011

Phone: (515) 294-7100
Fax: (515) 294-2315
E-mail: day@iastate.edu

Professional Experience

2000 -	Assistant Professor Department of Biomedical Sciences, Iowa State University, Ames, IA
2002 -	Chairman Neuroscience Program, Iowa State University, Ames, IA
2000 -	Faculty Neuroscience Program, Iowa State University, Ames, IA
2001 -	Faculty Toxicology Program, Iowa State University, Ames, IA
1997 - 2000	Assistant Professor Department of Pharmacology & Toxicology, Michigan State University, East Lansing, MI
1996 - 1997	Visiting Assistant Professor Department of Zoology, Michigan State University, East Lansing, MI
1994 - 1996	Field Representative Resource Exchange International, Hanoi Medical College, Hanoi, Vietnam
1993 - 1994	Post-Doctoral Research Associate Department of Pharmacology & Toxicology, Michigan State University, East Lansing, MI
1991 - 1993	Pre-Doctoral Research Assistant Department of Zoology, Michigan State University, East Lansing, MI
1989 - 1991	Pre-Doctoral Research Assistant Department of Pharmacology & Toxicology, Michigan State University, East Lansing, MI
1988 - 1989	Pre-Doctoral Research Fellow College of Natural Science, Michigan State University, East Lansing, MI

Education

1993	Ph.D. Pharmacology & Toxicology, Michigan State University
1990	M.S. Zoology, Michigan State University
1990	B.S. Education, Michigan State University
1988	B.S. Biology, Kansas State University

Professional Affiliations

	British Society for Parasitologists
	American Society for Parasitologists
	American Society of Tropical Medicine & Hygiene
	Society for Neuroscience

Service to the Professional Community

2000 - 2003	Editorial Board Parasitology, Cambridge University Press
2000 -	Study Section National Institutes of Health, Tropical Medicine & Parasitology, Temporary ad hoc Member
	Ad hoc Reviewer American Journal of Tropical Medicine & Hygiene Biochemical Pharmacology Experimental Parasitology International Journal for Parasitology Journal of Parasitology Journal of Comparative Physiology Molecular and Biochemical Parasitology Molecular Neurobiology Neurotoxicology Peptides Proceedings of the National Academy of Sciences Southern Medical Journal

Service to the University Community

2003 -

Student Awards Committee
College of Veterinary Medicine, Iowa State University

2001 -

Faculty Governance Committee
College of Veterinary Medicine, Iowa State University

2001 - 2002

Pharmacology/Phsyiology Search Committee (3 positions)
Department of Biomedical Sciences, Iowa State University

2001 - 2004

Neuroscience Program Supervisoty Committee
Neuroscience Program, Iowa State University

2001 - 2004

Graduate Admissions Committee, Chair
Neuroscience Program, Iowa State University

2000 - 2003

Research Advisory Council
College of Veterinary Medicine, Iowa State University

2003	Research Advisory Council Subcommittee Review of University Bailey Research Award Grants
2003	Research Advisory Council Subcommittee Review of University Reserach Grant Proposals
2002	Research Advisory Council Subcommittee Review of 2002-2003 USDA Formula Funds Proposals
2002	Research Advisory Council Subcommittee Chair, Review of 2002-2003 HLI (Healthy Livestock Initiative) Proposals
2001	Research Advisory Council Subcommittee Assessment and Re-evaluation of College of Veterinary Medicine Intramural Research Funding Programs
2001	Research Advisory Council Subcommittee Review of 2001-2002 HLI (Healthy Livestock Initiative) Proposals
2001	Research Advisory Council Subcommittee Review of 2001-2002 IHLAC (Iowa Healthy Livestock Advisory Council) Proposals
2001	Research Advisory Council Subcommittee Review of 2001-2002 USDA Formula Funds Proposals
2000	Research Advisory Council Subcommittee Review of 2000-2001 IHLAC (Iowa Healthy Livestock Advisory Council) Contingency Proposals
2000	Research Advisory Council Subcommittee Review of 2000-2001 USDA Formula Fund Proposals

1998 - 2000

Committee Serving Under-Represented Minorities
Department of Pharmacology & Toxicology, Michigan State University

Teaching Experience

2003 -	Cellular, Molecular and Developmental Neurobiology, Lecturer NEURO/BMS 556, Iowa State University
2002 -	General Principles of Pharmacology, Lecturer BMS 354/554 General Pharmacology, Iowa State University
2002 -	Autonomic Pharmacology, Lecturer BMS 354/554 General Pharmacology, Iowa State University
2001 -	Circulation of Specialized Regions, Lecturer BMS 552 Physiology, Iowa State University
1999	Antiparasitic Agents, Lecturer PHM 820 Cellular & Molecular Pharmacology, Michigan State University
1998	Veterinary Parasitology, Lecturer PHM 556 Veterninary Pharmacology, Michigan State University
1996 - 1997	Neurobiology, Course Coordinator & Lecturer ZOL/PSL 402 Neurobiology, Michigan State University
1996 - 1998	Passive Properties of Biological Membranes, Lecturer PHM 827 Physiology & Pharmacology of Excitable Cells, Michigan State University
1991 - 1998	Renal Toxicology, Lecturer PHM 450 Toxicology, Michigan State University
1991 - 1992	Potassium Channels, Lecturer ZOL/PSL 827 Neurobiology, Michigan State University
1989	Comparative Neurobiology, Graduate Assistant ZOL 827 Comparative Neurobiology, Michigan StateUniversity
1990	General Biology, Student Teacher Portland High School, Portland, MI
1990	Earth Science, Student Teacher Portland High School, Portland, MI
1986 - 1987	Pre-College Algebra, Course Instructor Kansas State University

Research Funding

2002 - 2003	Exploring New Control Strategies in Soybean Cyst Nematodes Role: Principal Investigator Funding Agency: Iowa State University Type of Proposal: University Research Grant Direct Costs / Duration: $18,000 / 1 yr.
2002 - 2004	Exploring New Drug Targets in Parasitic Helminths Role: Principal Investigator Funding Agency: Healthy Livestock Initiative of Iowa Type of Proposal: Position Support Grant Direct Costs / Duration: $62,500 / 2.5 yrs
2000 - 2004	Structure and Function of Schistosome Neuropeptide F Role: Principal Investigator Funding Agency: NIH/NIAID Tropical Medicine & Parasitology Type of Proposal: R01 Direct Costs / Duration: $700,000 / 4 yrs.
1998 - 2001	Resistance to Praziquantel: An Emerging Problem Role: Co-Investigator Funding Agency: NIH/NIAID Tropical Medicine & Parasitology Type of Proposal: R01 Direct Costs / Duration: $1,329,967 / 3 yrs.
1998	Structure & Function of FMRFamide-Related Peptide Receptors Role: Principal Investigator Funding Agency: Pharmacia & Upjohn Direct Costs / Duration: $25,000 / 1 yr.
1998 - 2000	Praziquantel Resistance in Egypt Role: Visiting Expert Agency: World Health Organization - TDR Type of Proposal: Research Capability Strengthening Grant Direct Costs / Duration: $98,900 / 3 yrs.
1995 - 1999	*Analysis of Ion Channels in S. mansoni* Muscle Fibers** Role: Co-Investigator Funding Agency: NIH/NIAID Tropical Medicine & Parasitology Type of Proposal: R01 Direct Costs / Duration: $581,987 / 4 yrs.

Invited Seminars

2002	Schistosomiasis in Egypt: Morbidity Control and the Emergence of Resistance Toxicology Program, Iowa State University, Ames, IA
2002	Schistosomiasis in Egypt: Morbidity Control and the Emergence of Resistance Department of Veterinary Pathology, Iowa State University, Ames, IA
2001	Pharmacology of Schistosomes: Serotonin and Neuropeptides Schistosomiasis Congress, Recife, Brazil
2001	Figuring Out Flukes: The Current State of Schistosomiasis Research Department of Biochemistry and Biology, Queen's University of Belfast, Belfast, Northern, Ireland.
2001	The Potential of Resistance to Praziquantel in Egypt Department of Biomedical Sciences, Iowa State University, Ames, IA
2001	Resistance to Praziquantel Keystone Symposium: Molecular Helminthology, An Integrated Approach, Taos NM
2000	Neurotransmission in Parasitic Worms Neuroscience Program, Iowa State University, Ames IA
2000	Exploring New Drug Targets. How will the Next Generation of Anthelmintic Drugs be Discovered? Department of Biology, Cayey University, Cayey, Peurto Rico
1999	Neuropeptides in Parasitic Platyhelminths Department of Biomedical Sciences, Iowa State University, Ames, IA
1999	Neuropeptides in Parasitic Platyhelminths Center for Tropical and Emerging Global Diseases, Univ. of Georgia, Athens, GA
1999	People, Parasites and Peptides Department of Biology, University of Alaska Anchorage, Anchorage, AK
1999	People, Parasites and Peptides Department of Biology, University of Central Arkansas, Conway, AR
1998	Peptidergic Transmission in Parasitic Platyhelminths Department of Biology, University of Toledo, Toledo, OH
1996	FMRFamide-like Peptides in Schistosomes Keystone Symposium: Molecular Helminthology, An Integrated Approach

Publications

2003	*A functionally atypical amidating enzyme from the human parasite Schistosoma mansoni.* G.R. Mair, M.J. Niciu, M.T. Stewart, G. Brennan, H.H. Omar, D.W. Halton, R. Mains, B.A. Eipper, A.G. Maule and T.A. Day. FASEB Journal, in press.
2003	*Muscle organisation of Schistosoma mansoni* ceracria.** G.R. Mair, A.G. Maule, B. Fried, T.A. Day and D.W. Halton, Journal of Parasitology, in press
2002	*Neuropeptide F (NPF) from the land planarian, Arthurdendyus triangulatus: gene organisation and expression* (2002). P.M. Dougan, G.R. Mair, D.W. Halton, W.J. Curry T.A. Day and A.G. Maule. Journal of Comparative Nuerology 454:58-64.
2002	Functional voltage-gated Ca2+ channels in muscle fibers of the Platyhelminth Girardia tigrina (2002). P. Cobbett and T.A. Day. Comparative Biochemistry and Physiology Part A 134:593-605.
2002	Neuropeptide Signaling Systems - Potential Drug Targets for Parasite and Pest Control (2002). A.G. Maule, A. Mousley, N.J. Marks, T.A. Day, D.P. Thompson, T.G. Geary and D.W. Halton. Current Topics in Medicinal Chemistry 2:733-758.
2001	*Stability and reproductive fitness of S. mansoni* isolates with decreased sensitivity to praziquantel** (2001). S. William, A. Sabra, F. Ramzy, M. Mousa, Z. Demerdash, T.A. Day, J.L. Bennett and S. Botros. International Journal for Parasitology 31:1093-1100.
2001	Cloning and characterization of a muscle isoform of a Sodium Potassium ATPase alpha subunit (SNaK1) from Schistosoma mansoni (2001). P.J. Skelly, P.M. Dougan, A.G. Maule, T.A. Day and C.B. Shoemaker. Parasitology 123:277-284.
2001	Physiological effects of FMRFamide-related peptides and classical transmitters on isolated muscle fibres of the turbellarian Procerodes littoralis (2001). C.G. Moneypenny, N. Kreshchencko, T.A. Day, C. Moffett, D.W. Halton and A.G. Maule. Parasitology 122:447-455.
2001	*Praziquantel-induced tegumental damage in vitro* is diminished in schistosomes derived from praziquantel-resistant infections** (2001). S. William, S. Butros, M. Ismail, A. Farghally. T.A. Day and J.L. Bennett. Parasitology 122:63-66.
2000	Confocal microscopal study of the musculature of adult Schistosoma mansoni (2000). G.R. Mair, A.G. Maule, T.A. Day and D.W. Halton Parasitology 121:163-170.
2000	Functional ryanodine receptor channels in flatworm muscle fibres (2000). T.A. Day, J. Haithcock, M. Kimber and A.G. Maule. Parasitology 120:417-422.
2000	Pharmacology of FMRFamide-related peptides (FaRPs) in helminths (2000). T.G. Geary, N.J. Marks, A.G. Maule, J.W. Bowman, S.J. Alexander-Bowman, T.A. Day, M.J. Larsen, T.M. Kubiak, J.P. Davis and D.P. Thompson. Annals of the New York Academy of Sciences 897:212-227.
1999	Parasitic Peptides! The structure and function of neuropeptides in parasitic worms (1999). T.A. Day and A.G. Maule. Peptides 20:999-1019.
1999	Resistance to praziquantel: direct evidence from parasites isolated from Egyptian villagers (1999). M. Ismail, A. Metwally, S. William, S. Botros, A. Farghally, L. Tao, T.A. Day, J.L. Bennett. American Journal of Tropical Medicine & Hygiene 60:932-935.
1998	*The metalloprotease inhibitor 1,10-phenanthroline affects Schistosoma mansoni* motor activity, egg laying and viability** (1998). T.A. Day and G.Z. Chen. Parasitology 116:319-325.
1997	The development of resistance to anthelmintics: a perspective with an emphasis on the antischistosomal drug praziquantel (1997). J.L Bennett, T.A. Day, L. Tao, M. Ismail, A. Farghally, Experimental Parasitology 87:260-267.
1997	Physiological effects of platyhelminth FMRFamide-related peptides (FaRPs) on the somatic musculature of the monogean Diclodophora merlangi (1997). C.G. Moneypenny, A.G. Maule, C. Shaw, T.A. Day, R.A. Pax and D.W. Halton, Parasitology 115:281-288.
1997	*Structure-activity relationships of FMRFamide-related peptide-induced contractions of Schistosoma mansoni* muscle** (1997). T.A. Day, A.G. Maule, C. Shaw, and R.A. Pax, Peptides 18:917-921.
1996	Neurobiology of Helminth Parasites (1996). A.G. Maule, D.W. Halton, T.A. Day, R.A. Pax and C. Shaw. Chapter 6, Analytical Parasitology, Eds: M.T. Rogan & P.S. Craig, Heidelberg: Springer-Verlag.
1996	Neuromuscular physiology and pharmacology of parasitic flatworms (1996). R.A. Pax, T.A. Day, C.L. Miller and J.L. Bennett, Parasitology 113:S83-S96.
1996	S. mansoni: L-glutamate-induced contractions in isolated muscle fibers; evidence for a glutamate transporter (1996). C.L. Miller, T.A. Day, J.L. Bennett and R.A. Pax, Experimental Parasitology 84:410-419.
1996	*Cholinergic inhibition of muscle fibres isolated from Schistosoma mansoni* (Trematoda: Digenea)** (1996). T.A. Day, G.Z. Chen, C. Miller, M. Tian, J.L. Bennett and R.A. Pax, Parasitology 113:55-61.
1995	Analysis of the kinetics and voltage-dependency of transient and delayed K+ currents in muscle fibers isolated from the flatworm Schistosoma mansoni (1995). T.A. Day, E. Kim, J.L. Bennett and R.A. Pax, Comparative Biochemistry and Physiology 111A:79-87.
1995	*Immunohistochemical localisation of a Shaker-related potassium channel protein in Schistosoma mansoni* (Trematoda: Digenea)*(1995). E. Kim, T.A. Day, N.J. Marks, R.N. Johnston, D.W. Halton, C. Shaw, G.Z. Chen, J.L. Bennett and R.A. Pax, Experimental Parasitology* 81:421-429.
1995	*Cloning and functional expression of a Shaker-related voltage-gated potassium channel gene from the flatworm Schistosoma mansoni* (Trematoda: Digenea)** (1995). E. Kim, T.A. Day, J.L. Bennett and R.A. Pax, Parasitology 110:171-180.
1994	Platyhelminth FMRFamide-related peptides (FaRPs) contract Schistosoma mansoni (Trematoda: Digenea) muscle fibres in vitro (1994). T.A. Day, A.G. Maule, C. Shaw, D.W. Halton, S. Moore, J.L. Bennett and R.A. Pax, Parasitology 109:455-459.
1993	Serotonin and its requirement for contractility in muscle fibres isolated from Schistosoma mansoni (1994). T.A. Day, J.L. Bennett and R.A. Pax, Parasitology 108:425-432.
1993	Voltage-gated currents in muscle cells of Schistosoma mansoni (1993). T.A. Day, N. Orr, J.L. Bennett and R.A. Pax, Parasitology 106:471-477.
1992	Praziquantel: The enigmatic antiparasitic (1992). T.A. Day, J.L. Bennett and R.A. Pax, Parasitology Today 8:342-344.
1992	Schistosoma mansoni: Patch-clamp study of a non-selective cation channel in the outer tegumental membrane of females (1992). T.A. Day, M.L. Lewis, J.L. Bennett and R.A. Pax, Experimental Parasitology 74:348-356.
1991	*Studies on muscle cells isolated from Schistosoma mansoni: A calcium-dependent potassium channel* (1991). K.L. Blair, T.A. Day, M.L. Lewis, J.L. Bennett and R.A. Pax, Parasitology 102:251-258.

Presentations at National and International Meetings

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