Tim Day's Lab

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Muscle organisation of Schistosoma mansoni ceracria. G.R. Mair, A.G. Maule, B. Fried, T.A. Day and D.W. Halton, Journal of Parasitology (submitted).    
Neuropeptide F (NPF) from the land planarian, Arthurdendyus triangulatus: gene organisation and expression. P.M. Dougan, G.R. Mair, D.W. Halton, W.J. Curry T.A. Day and A.G. Maule. Journal of Comparative Nuerology (in press).     
Functional voltage-gated Ca2+ channels in muscle fibers of the Platyhelminth Dugesia tigrina. P. Cobbett and T.A. Day. Comparative Biochemistry and Physiology (in press).    
Neuropeptide Signaling Systems - Potential Drug Targets for Parasite and Pest Control. A.G. Maule, A. Mousley, N.J. Marks, T.A. Day, D.P. Thompson, T.G. Geary and D.W. Halton. Current Topics in Medicinal Chemistry 2:733-758.    
Cloning and characterization of a muscle isoform of a Sodium Potassium ATPase alpha subunit (SNaK1) from Schistosoma mansoni (2001). P.J. Skelly, P.M. Dougan, A.G. Maule, T.A. Day and C.B. Shoemaker. Parasitology 123:277-284.   
Physiological effects of FMRFamide related peptides and classical transmitters on isolated muscle fibres of the turbellarian, Procerodes littoralis (2001). C.G. Moneypenny, N. Kreshchencko, T.A. Day, C. Moffett, D.W. Halton and A.G. Maule. Parasitology 122:447-455.   
Stability and reproductive fitness of S. mansoni isolates with decreased sensitivity to praziquantel (2001). S. William, A. Sabra, F. Ramzy, M. Mousa, Z. El-Demerdash, T.A. Day, J.L. Bennett and S. Botros. International Journal for Parasitology 31:1093-1100.     
Confocal microscopical study of the musculature of adult Schistosoma mansoni (2000). G.R. Mair, A.G. Maule, T.A. Day and D.W. Halton. Parasitology 121:163-170.    
Praziquantel-induced tegumental damage in vitro is diminished in schistosomes derived from praziquantel-resistant infections (2000). S. William, S. Butros, M. Ismail, A. Farghally. T.A. Day and J.L. Bennett. Parasitology 122:163-166.    
Functional ryanodine receptor channels in flatworm muscle fibres (2000). T.A. Day, J. Haithcock, M. Kimber and A.G. Maule. Parasitology 120:417-422.    
Pharmacology of FMRFamide-related peptides (FaRPs) in helminths (2000). T.G. Geary, N.J. Marks, A.G. Maule, J.W. Bowman, S.J. Alexander-Bowman, T.A. Day, M.J. Larsen, T.M. Kubiak, J.P. Davis and D.P. Thompson. Annals of the New York Academy of Sciences 897:212-227.  
Parasitic Peptides! The structure and function of neuropeptides in parasitic worms (1999). T.A. Day and A.G. Maule. Peptides 20:999-1019.    
Resistance to praziquantel: direct evidence from parasites isolated from Egyptian villagers (1999). M. Ismail, A. Metwally, S. William, S. Botros, A. Farghally, L. Tao, T.A. Day, J.L. Bennett. American Journal of Tropical Medicine & Hygiene 60:932-935.    
The metalloprotease inhibitor 1,10-phenanthroline affects Schistosoma mansoni motor activity, egg laying and viability (1998). T.A. Day and G.Z. Chen. Parasitology 116:319-325. 
The development of resistance to anthelmintics: a perspective with an emphasis on the antischistosomal drug praziquantel (1997). J.L Bennett, T.A. Day, L. Tao, M. Ismail, A. Farghally, Experimental Parasitology 87:260-267.     
Physiological effects of platyhelminth FMRFamide-related peptides (FaRPs) on the somatic musculature of the monogean Diclodophora merlangi (1997). C.G. Moneypenny, A.G. Maule, C. Shaw, T.A. Day, R.A. Pax and D.W. Halton, Parasitology 115:281-288.     
Structure-activity relationships of FMRFamide-related peptide-induced contractions of Schistosoma mansoni muscle (1997). T.A. Day, A.G. Maule, C. Shaw, and R.A. Pax, Peptides 18:917-921.     
Neurobiology of Helminth Parasites (1996). A.G. Maule, D.W. Halton, T.A. Day, R.A. Pax and C. Shaw. Chapter 6, Analytical Parasitology, Eds: M.T. Rogan & P.S. Craig, Heidelberg: Springer-Verlag.  
Neuromuscular physiology and pharmacology of parasitic flatworms (1996). R.A. Pax, T.A. Day, C.L. Miller and J.L. Bennett, Parasitology 113:S83-S96.     
S. mansoni: L-glutamate-induced contractions in isolated muscle fibers; evidence for a glutamate transporter (1996). C.L. Miller, T.A. Day, J.L. Bennett and R.A. Pax, Experimental Parasitology 84:410-419.   
Cholinergic inhibition of muscle fibres isolated from Schistosoma mansoni (Trematoda: Digenea) (1996). T.A. Day, G.Z. Chen, C. Miller, M. Tian, J.L. Bennett and R.A. Pax, Parasitology 113:55-61.   
Analysis of the kinetics and voltage-dependency of transient and delayed K+ currents in muscle fibers isolated from the flatworm Schistosoma mansoni (1995). T.A. Day, E. Kim, J.L. Bennett and R.A. Pax, Comparative Biochemistry and Physiology 111A:79-87.   
Immunohistochemical localisation of a Shaker-related potassium channel protein in Schistosoma mansoni (Trematoda: Digenea)(1995). E. Kim, T.A. Day, N.J. Marks, R.N. Johnston, D.W. Halton, C. Shaw, G.Z. Chen, J.L. Bennett and R.A. Pax, Experimental Parasitology 81:421-429.   
Cloning and functional expression of a Shaker-related voltage-gated potassium channel gene from the flatworm Schistosoma mansoni (Trematoda: Digenea) (1995). E. Kim, T.A. Day, J.L. Bennett and R.A. Pax, Parasitology 110:171-180.     
Platyhelminth FMRFamide-related peptides (FaRPs) contract Schistosoma mansoni (Trematoda: Digenea) muscle fibres in vitro (1994). T.A. Day, A.G. Maule, C. Shaw, D.W. Halton, S. Moore, J.L. Bennett and R.A. Pax, Parasitology 109:455-459.     
Serotonin and its requirement for contractility in muscle fibres isolated from Schistosoma mansoni (1994). T.A. Day, J.L. Bennett and R.A. Pax, Parasitology 108:425-432.   
Voltage-gated currents in muscle cells of Schistosoma mansoni (1993). T.A. Day, N. Orr, J.L. Bennett and R.A. Pax, Parasitology 106:471-477.   
Praziquantel: The enigmatic antiparasitic (1992). T.A. Day, J.L. Bennett and R.A. Pax, Parasitology Today 8:342-344.   
Schistosoma mansoni: Patch-clamp study of a non-selective cation channel in the outer tegumental membrane of females (1992). T.A. Day, M.L. Lewis, J.L. Bennett and R.A. Pax, Experimental Parasitology 74:348-356.   
Studies on muscle cells isolated from Schistosoma mansoni: A calcium-dependent potassium channel (1991). K.L. Blair, T.A. Day, M.L. Lewis, J.L. Bennett and R.A. Pax, Parasitology 102:251-258.   
Presentations at National and International Meetings

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