Iowa State University

Iowa State University

2009-2011 Courses and Programs

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Veterinary Microbiology and Preventive Medicine

300 |400 |Graduate Courses |500 |600 |

Michael Wannemuehler, Interim Chair of Department
Distinguished Professors: Roth
Distinguished Professors (Emeritus): Beran, Cheville, Kaeberle, Ross, Switzer
Professors: Minion, Nolan, Phillips, Platt, Reynolds, Rosenbusch, Thoen, Uhlenhopp, Wannemuehler, Yoon, Zhang, Zimmerman
Professors (Emeritus): Hogle, Kramer, Moon
Professors (Collaborators): Carpenter, Kehrli, Nystrom-Dean, Schultz, Tabatabai, Thacker
Associate Professors: Cornick, Davis, Griffith
Associate Professors (Collaborators): Frey, Harp, Panigrahy, Richt, Sacco, Sharma, Zuerner
Assistant Professors: Bellaire, Blitvich, Miller, Sponseller
Assistant Professors (Collaborators): Anderson, Bannantine, Brockmeier, Faaberg, Halling, Lager, Register, Roof, Scupham, Stabel, Stanton, Vaughn, Vincent, Waters, Wesley
Instructor (Collaborator): Schlater
Lecturer: Brown
Clinician: Plummer

The Department of Veterinary Microbiology and Preventive Medicine offers instruction in the areas of bacteriology, mycology, virology, immunology, epidemiology and public health at the graduate level.

Microbiologic, immunologic, regulatory, and preventive medical aspects of infectious diseases of animals are emphasized in courses for students in the veterinary curriculum.

Professional Program of Study

For the professional curriculum in veterinary medicine leading to the degree doctor of veterinary medicine, see Veterinary Medicine, Curriculum.

The Department of Veterinary Microbiology and Preventive Medicine provides instruction on pathogenic bacteria, fungi, and viruses and their interaction with host animal species. Principles and applications of infectious diseases, immunity to disease, diagnostic methods for infectious diseases, and vaccinology are covered. Principles and applications of epidemiology, public health, preventive veterinary medicine, regulatory veterinary medicine and food safety are also emphasized.

Graduate Study

The department offers opportunities for the degree doctor of philosophy with a major in veterinary microbiology. A specialization in preventive medicine is an option for this degree. Graduates in the Veterinary Microbiology and Preventive Medicine programs have a broad understanding of the fundamental processes involved in infectious diseases, pathogenesis and immunology. They are able to effectively establish research programs, which involve complex biological systems and disease syndromes. They are also prepared to address microbial-based social, ethical and environmental problems. Graduates acquire effective written and oral communication skills which lead to successful research and teaching careers in the medical and veterinary sciences. The department also offers work towards the master of science with majors in veterinary microbiology or veterinary preventive medicine. A non-thesis master's option is available for majors in preventive medicine. Courses are open for students majoring in other graduate programs.

Prerequisite to graduate study is completion of coursework in general microbiology, biology, biochemistry, mathematical sciences, and physics. Candidates for the majors in veterinary microbiology should possess an undergraduate degree in biomedical science with emphasis in medical microbiology or the D.V.M. degree. Candidates for the major in preventive medicine should possess the D.V.M. degree.

The department also participates in the interdepartmental majors and programs in genetics, immunobiology, and MCDB (molecular, cellular, and developmental biology; see Index).

Each graduate student must demonstrate proficiency in English composition within two semesters in residence.

Courses primarily for professional curriculum students

V MPM 378. Case Study IV. (2-0) Cr. 2. S.Prereq: Second-year classification in veterinary medicine. Case-based applied learning that relates to the basic science courses. Emphasis on early integration of basic and clinical science concepts.

V MPM 380. Veterinary Immunology. (2-0) Cr. 2. S.Prereq: First-year classification in veterinary medicine. Structure and function of the immune system in animals.

V MPM 386. Veterinary Microbiology. (3-5) Cr. 5. F.Prereq: Second-year classification in veterinary medicine. Bacteria and fungi of veterinary importance with emphasis on mechanisms of disease production and laboratory diagnostic procedures.

V MPM 387. Veterinary Virology. (3-0) Cr. 3. S.Prereq: Second-year classification in veterinary medicine. Basic principles of animal virology. Pathogenesis of viral infections. The nature and ecology of viruses of veterinary and zoonotic importance.

V MPM 388. Public Health and the Role of the Veterinary Profession. (3-0) Cr. 3. S.Prereq: Second-year classification in veterinary medicine. Fundamental epidemiology, zoonotic diseases, occupational health, food safety, other public health topics.

V MPM 390. Topics in Veterinary History. (2-0) Cr. 1. S.8 weeks. Significant persons, noteworthy events, and pivotal scientific discoveries in the course of the development and advancement of veterinary medicine from ancient times to the present.

V MPM 409. Infectious Diseases of Captive Wild Animals. (0-2) Cr. 1. F.Prereq: Second year classification in veterinary medicine. Infectious diseases (bacterial, viral, and mycotic) of non-human primates, birds, ruminants, cold-blooded animals, marine mammals, and carnivores.

V MPM 437. Infectious Diseases and Preventive Medicine. (3-0) Cr. 3. S.Prereq: Third-year classification in veterinary medicine. Etiology, epidemiology, laboratory diagnosis, regulatory control and preventive medicine aspects of the infectious diseases of swine, sheep, goats, cattle and horses.

V MPM 486. Laboratory in Public Health. Cr. 1. Repeatable. F.S.Prereq: Fourth-year classification in veterinary medicine. Discussions, lectures, exercises and field trips related to veterinary public health.

V MPM 490. Independent Study. Cr. arr. Repeatable. F.S.SS.Prereq: Permission of instructor and department chair.

V MPM 491. CDC Epidemiology Elective Preceptorship. Cr. 6. F.S.SS.Introduction to preventive medicine, public health and the principles of applied epidemiology within the working atmosphere of the Centers for Disease Control.

V MPM 494. Zoo Preceptorship. Cr. 1-8. Repeatable. F.S.SS.Prereq: Fourth year classification in veterinary medicine. Elective course in zoo veterinary practice under guidance of approved veterinarians.

V MPM 496. International Preceptorship. (0-40) Cr. 1-12. Repeatable. F.S.SS.Prereq: Second-year classification in veterinary medicine. International Preceptorships and Study Abroad group programs. This course will provide opportunities for students to be involved in applied clinical, production, and/or research experiences in international locations. The course consists of 40 hour per week experiential learning opportunities.

Courses primarily for graduate students, open to qualified undergraduate students

V MPM 520. Medical Immunology I. (4-0) Cr. 4. F.Prereq: Micro 310 or V MPM 386, 3 credits in biochemistry. Nature of the immune system and its role in health and disease. Credit for either V MPM 520 or 575, but not both may be applied toward graduation.

V MPM 522. Principles of Epidemiology and Population Health. (Cross-listed with VDPAM). (3-0) Cr. 3. S.Prereq: Micro 310 or equivalent. Epidemiology and ecology of disease in populations. Disease causality and epidemiologic investigations. Issues in disease prevention, control, and eradication.

V MPM 536. Zoonoses and Environmental Health. (3-0) Cr. 3. Alt. S., offered 2010.Prereq: 386, 387 and 388 or equivalent or permission of instructor. Pathogensis and control of zoonotic diseases. Factors influencing transmission and survival of pathogenic microorganisms in the environment.

V MPM 540. Livestock Immunogenetics. (Cross-listed with An S, Micro). (2-0) Cr. 2. Alt. S., offered 2011.Prereq: An S 561 or Micro 575 or V MPM 520. Basic concepts and contemporary topics in genetic regulation of livestock immune response and disease resistance.

V MPM 542. Introduction to Molecular Biology Techniques. (Cross-listed with B M S, BBMB, BCB, EEOB, FS HN, GDCB, Hort, NREM, NutrS, VDPAM). Cr. 1. Repeatable. F.S.SS.Prereq: Graduate classification. Workshops in basic molecular biology techniques and related procedures. Satisfactory-fail only.
A. DNA Techniques. Includes genetic engineering procedures, sequencing, PCR, and genotyping. (F.S.SS.)
B. Protein Techniques. Includes fermentation, protein isolation, protein purification, SDS-PAGE, Western blotting, NMR, confocal microscopy and laser microdissection, immunophenotyping, and monoclonol antibody production. (S.SS.)
C. Cell Techniques. Includes immunophenotyping, ELISA, flow cytometry, microscopic techniques, and image analysis. (F.S.)
D. Plant Transformation. Includes Agrobacterium and particle gun-mediated transformation of tobacco, Arabidopsis, and maize, and analysis of transformants. (S.)
E. Proteomics. Includes two-dimensional electrophoresis, laser scanning, mass spectrometry, and database searching. (F.)

V MPM 565. Professional Practice in the Life Sciences. (Cross-listed with Pl P, Agron, An S, BCB, Hort, Micro). Cr. arr. Repeatable. S.Prereq: Graduate classification. Professional discourse on the ethical and legal issues facing life science researchers. Offered in modular format; each module is four weeks.
A. Professional Practices in Research. (Cr. 1.0) Good scientific practices and professional ethics in the life sciences.
B. Intellectual Property and Industry Interactions. (Cr. 0.5) Ethical and legal issues facing life scientists involved in research interactions with industry.

V MPM 575. Immunology. (Cross-listed with Micro). (3-0) Cr. 3. S.Prereq: 310. Humoral and cellular immune functions. Interactions between cells and factors of the immune system that result in health and disease. Micro 475L optional. Credit for either V MPM 575 or V MPM 520, but not both, may be applied toward graduation.

V MPM 586. Medical Bacteriology. (Cross-listed with Micro). (4-0) Cr. 4. F.Prereq: Permission of instructor. Bacteria associated with diseases of vertebrates, including virulence factors and interaction of host responses.

V MPM 586L. Medical Bacteriology Laboratory. (0-6) Cr. 2. F.Prereq: credit or enrollment in 586 or 625. Procedures used in isolation and identification of pathogenic bacteria, including molecular and genetic techniques used in research.

V MPM 587. Animal Virology. (4-0) Cr. 4.Prereq: Permission of instructor. The biology of animal viruses and pathgenic mechanisms in viral diseases.

V MPM 587L. Laboratory in Animal Virology. (0-3) Cr. 1.Prereq: Permission of the instructor. Basic laboratory techniques in virology.

V MPM 590. Special Topics. Cr. 1-5. Repeatable. F.S.SS.Prereq: Permission of instructor.

V MPM 596. International Preceptorship. (0-40) Cr. 1-12. Repeatable. F.S.SS.Prereq: Admission to graduate college. International Preceptorships and Study Abroad Group programs. This course will provide opportunties for students to be involved in applied clinical, production, and/or research experiences in international locations. The course consists of 40 hour per week experiential learning opportunties.

V MPM 599. Creative Component. Cr. arr.Prereq: Nonthesis M.S. Option only. A written report based on laboratory research, library reading, or topics related to the student's area of specialization and approved by the student's advisory committee.

Courses for graduate students

V MPM 604. Seminar. (1-0) Cr. 1. Repeatable. F.Satisfactory-fail only.

V MPM 608. Molecular Virology. (Cross-listed with Micro, Pl P). (3-0) Cr. 3. Alt. F., offered 2010.Prereq: BBMB 405 or GDCB 511. C. Miller, B. Blitvich, A. Miller. Advanced study of virus host-cell interactions. Molecular mechanisms of viral replication and pathogenesis.

V MPM 615. Molecular Immunology. (Cross-listed with BBMB, Micro). (3-0) Cr. 3. Alt. F., offered 2009.Prereq: BBMB 405 or 502. Current topics in molecular aspects of immunology: T and B cell receptors; major histocompatibility complex; antibody structure; immunosuppressive drugs and viruses; and intracellular signalling pathways leading to expression of genes that control and activate immune function.

V MPM 625. Mechanisms of Bacterial Pathogenesis. (Cross-listed with Micro). (4-0) Cr. 4. Alt. S., offered 2011.Prereq: Credit in Biochemistry and Microbiology. Review of current concepts in specific areas of microbial pathogenesis including the genetic basis for bacterial disease, genetic regulation and control of virulence factors and their mechanisms of action, and host-pathogen interactions at the cellular and molecular levels. The application of microbial genetics to understanding pathogenesis will be included.

V MPM 629. Advanced Topics in Cellular Immunology. (2-0) Cr. 2. Alt. S., offered 2010.Prereq: 520 or 575. Current topics and literature in cellular immunology. Topics include thymocyte development and selection, T cell interactions with antigen presenting cells, and lymphocyte effector functions.

V MPM 660. Pathogenesis of Persistent Infections. (Cross-listed with V Pth). (2-0) Cr. 2. Alt. S., offered 2011.Prereq: Permission of instructor. Study of current knowledge related to host pathogen interactions during persistent and chronic infections by bacteria, viruses and parasites.

V MPM 690. Current Topics. Cr. 1-3. Repeatable. F.S.SS.Prereq: Permission of instructor. Colloquia or advanced study of specific topics in a specialized field.
A. Immunology
B. Infectious Diseases

V MPM 698. Seminar in Molecular, Cellular, and Developmental Biology. (Cross-listed with MCDB, BBMB, GDCB, Micro). (2-0) Cr. 1-2. Repeatable. F.S.Student and faculty presentations.

V MPM 699. Research. Cr. arr. Repeatable.