Iowa State University

Iowa State University

2009-2011 Courses and Programs

Iowa State University Catalog

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200 |300 |400 |

Minor administered by the College of Engineering

Supervisory Committee: P. Reilly (Chair), A. Bastawros, T. Kim, H. van Leeuwen, S. Pandey, G. Mirka, L. Genalo, P. Shrotriya

Undergraduate Study

The bioengineering minor at Iowa State University is an interdisciplinary program that complements a student's major discipline by providing additional insight into the interactions between various engineering disciplines and biological systems, emphasizing new ways of solving biological problems. The program provides students with unique educational experiences to apply engineering skills and create new biobased products and devices.

The program is open to all undergraduate engineering students at Iowa State University. This minor will provide students with a foundation of core Bioengineering knowledge, on which tracks will be superimposed to provide in-depth exposure to targeted areas of specialization. In addition to the core courses – - and 202 – students will complete coursework identified in the following tracks:

Bioinformatics and Systems Biology: BioE 325, BCB 211, 401, 402, and 442.

Biomaterials and Biomechanics: BioE 352, Ch E 440, Ex Sp 355, and Mat E 456.

Biomicrosystems: BioE 341, 341L, 450, 450L, and 428.

Biosystems and Environmental Engineering: A E 216 and 480, BioE 411/511, Ch E 415 and 427, and C E 421/521.

Courses primarily for undergraduate students

BioE 201. Introduction to Bioengineering I. (3-0) Cr. 3.Prereq: Chem 167. An exploration of cell structure and function, cellular metabolism, types of life forms, energy transport and use, biomolecule structure and function, and enzyme structure, function, and kinetics, with strong mathematical emphasis.

BioE 202. Introduction to Bioengineering II. (3-0) Cr. 3.Prereq: BIOE 201. Feedback loops in biological systems, cell and microbial growth patterns, fermentation kinetics. Biotechnology in diseases, wastewater treatment, genetic engineering of bacteria, fungi, plants, and animals, and biosensor operation. Strong mathematical emphasis.

BioE 325. Systems Biology for Engineering. (3-0) Cr. 3.Prereq: 202, Math 267. Review of systems approaches for modeling. Introduction or review of methods for gene regulation in cells and how to model them. Auto regulation of gene networks. Feedforward modeling, timing considerations. Feedback mechanisms. Kinetic and rate-limiting steps.

BioE 341. BioMEMs and Nanotechnology. (3-0) Cr. 3.Prereq: 202. Overview of Micro-Electro-Mechanical-System (MEMS) technologies for bioengineering, fundamentals of microfluidic device design, fabrication, and characterization, survey of microfluidic functional building blocks for lab-on-a-chip applications including mixers, valves, channels, and chambers. Topics of nanotechnology in bioengineering, nanoscale building block technologies for bioengineering including self-assembling, surface chemical treatment, nano-imprinting, nano-particles, nano-tubes, nano-wires, and stimuli-responsive biomaterials.

BioE 341L. BioMEMS and Nanotechnology Laboratory. (0-3) Cr. 1.Prereq: 202, concurrent enrollment in 341. Introductory laboratory course accompanying BioE 341. Design, fabrication, and characterization of BioMEMS lab-on-a-chip devices and nanoscale techniques for bioengineering. Student group projects. BioE341L not a necessary corequisite with BioE341.

BioE 352. Molecular, Cellular and Tissue Biomechanics. (3-0) Cr. 3.Prereq: 201, E M 324, Mat E 272. Introduction to the anatomy of the musculoskeletal system and connective tissue. Range of movement, joint dislocation, bone deformity and fracture. Application of continuum mechanics to both living and non-living systems. Laws of motion, free-body diagrams and simple force analysis of musculoskeletal system. Biomechanical response of soft and hard tissues with emphasis on microstructure and mechanical properties. Applications to bioengineering design.

BioE 411. Bioprocessing and Bioproducts. (Cross-listed with A E, BSE, C E). (3-0) Cr. 3. F.Prereq: A E 216 or equivalent, Math 160 or 165, one of Chem 167 or higher, Biol 173 or 211 or higher or BRT 501, senior or graduate classification. Sustainability, cleaner production. Taxonomy, kinetics, metabolism, aerobic and anaerobic fermentation. Biofuels, bioenergy and coproducts. Mass/energy balances, process integration, pretreatment, separation. Membrane reactors, bioelectrolysis, microbial fuel cells, nanotechnology, genetic engineering, mutagenesis.

BioE 428. Image Processing with Biomedical Applications. (3-0) Cr. 3.Prereq: E E 324. Review of signal processing, linear algebra, probability. Image sampling and quantization. Image transforms, image enhancement, image denoising/restoration. Tomographic reconstruction, segmentation and registration, recognition and shape analysis and applications in Computer Aided disease Detection (CAD).

BioE 450. Biosensing. (3-0) Cr. 3.Prereq: 202. Overview of biosensors and bioanalytical challenges; designing for performance including various analytical problems, ion-selective membranes, characteristics of enzymes and basics of bioaffinity sensing; fundamentals of bioselective layers including depositing films and membranes, surfaces for immobilization and bioselective agents; survey of different biosensing technologies including electroanalytical, biomembrane, optical, and acoustic-wave based sensors.

BioE 450L. Biosensing Laboratory. (0-3) Cr. 1.Prereq: 202, concurrent enrollment in BioE 450. Laboratory course accompanying BioE 450. Design, fabrication, and characterization of various electrical, chemical, polymer, optical and acoustic sensors. Lab is not a necessary corequisite with BioE 450.