Iowa State University

Iowa State University

2007-2009 Courses and Programs

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Molecular, Cellular, and Developmental Biology (MCDB)

Graduate Courses | www.mcdb.iastate.edu

(Interdepartmental Graduate Major)

Program Executive Committee: K. M. Johansen, Chair; G. Phillips, W. A. Miller

Participating Faculty: K. M. Johansen, Chair; L. Ambrosio, I. L. Anderson, A. Andreotti, L. Bartholomay, D. Bassham, T. Baum, G. Beattie, P. Becraft, J. Beetham, D. C. Beitz, M. Bhattacharyya, D. Birt, B. Blitvich, A. Bogdanove, B. Bonning, B. Brehm-Stecher, C. Coffman, D. Dobbs, J. Essner, C. F. Ford, D. Hannapel, E. R. Henderson, T. Huiatt, T. S. Ingebritsen, J. Johansen, K. M. Johansen, D. Jones, R. Jurenka, A. Kanthasamy, C. Komar, C. Lashbrook, M. Lee, C. Link, G. Macintosh, C. Miller, W. A. Miller, F. C. Minion, A. M. Myers, B. J. Nikolau, M. Nilsen-Hamilton, L. Nolan, J. Ourednik, V. Ourednik, R. Peters, C. Petersen, G. Phillips, J. Powell-Coffman, J. Reecy, R. M. Robson, D. S. Sakaguchi, K. Schalinske, P. S. Schnable, S. S. Shen, M. Shogren-Knaak, M. H. Spalding, C. Stahl, L. Tabatabai, R. W. Thornburg,C. K. Tuggle, E. Vollbrecht, D. F. Voytas, S. Whitham, E. S. Wurtele, Y. Yin, E. Yu

Undergraduate Study

A special program in molecular, cellular, and developmental biology is not offered for the baccalaureate. Undergraduates wishing to prepare for graduate study in molecular, cellular, and developmental biology should elect courses in biochemistry, biology, genetics, microbiology; and mathematics through calculus; chemistry through organic; and one year of physics. Biol 313, 313L, 314, and 314L are recommended to undergraduates desiring an introduction to this area.

Graduate Study

Work is offered for the master of science and doctor of philosophy degrees with a major in molecular, cellular, and developmental biology in several cooperating departments: Agronomy; Animal Science; Biochemistry, Biophysics & Molecular Biology; Biomedical Sciences; Entomology; Food Science and Human Nutrition; Genetics, Development and Cell Biology; Horticulture; Physics & Astronomy; Plant Pathology; Veterinary Microbiology & Preventive Medicine; Veterinary Pathology.

Facilities and qualified faculty are available in these departments for conducting fundamental research in the various aspects of molecular, cellular, and developmental biology. Ongoing research projects include molecular and cellular studies of viral, prokaryotic, plant, and animal systems.

Students may enter the MCDB major in one of two ways: they may apply to and be accepted into the major directly or they may formally apply to the major after being accepted by a participating department. Students admitted into MCDB will take MCDB 697 (Graduate Research Rotations) in their first two semesters and choose a major professor from the participating faculty by the end of their second semester. Students admitted by a department will choose a major professor from the participating faculty in that department. All Ph.D. students take a core curriculum consisting of the following courses: one year of biochemistry (BBMB 404, 405 or BBMB 501, 502), molecular biology (GDCB or BBMB 676, or MCDB 502 or VMPM 608), cell biology (GDCB 528, 529, 640 or BBMB 645 or BMS 575), developmental biology (GDCB 512 or 533), and seminar in MCDB (MCDB 698). In seminar, students will make journal and research presentations and attend MCDB seminars. M.S. students take the above core but may delete either the molecular genetics, cell biology, or developmental biology component. Additional coursework is selected to meet departmental requirements and to satisfy individual student research interests. All graduate students are required to teach as part of their training for an advanced degree.

Students minoring in molecular, cellular, and developmental biology at the Ph.D. level must meet the following requirements: one year of biochemistry (BBMB 404, 405, or BBMB 501, 502; one course from two of the above three areas: molecular biology (MCDB 502, 511, 545, or 676, or Micro 502, or VMPM 608), cell biology (MCDB 528, 529 or 640, or BBMB 645 or BMS 575), developmental biology (MCDB 512 or 533); and a semester of MCDB 698 (seminar in MCDB) each year.

Courses primarily for graduate students

MCDB 640. Signal Transduction. (Cross-listed with GDCB, BBMB). (3-0) Cr. 3. Alt. S., offered 2008. Prereq: GDCB 528, BBMB 404. Mechanisms and components of cellular signal transduction including receptors, G-proteins, second messengers, protein phosphorylation, other post-translational protein modications, and transcriptional regulation.

MCDB 676. Biochemistry of Gene Expression in Eucaryotes. (Cross-listed with BBMB). (2-0) Cr. 2. Alt. S., offered 2008. Prereq: BBMB 404 or 501, 405 or 502 or GDCB 511. Analysis of the biochemical processes involved in expression of eucaryotic genes and the regulation thereof, including RNA polymerase, transcriptional regulatory proteins, enhancers and silencers, chromosome structure, termination, RNA processing, RNA transport, RNA turnover, translational regulation, protein turnover.

MCDB 697. Graduate Research Rotation. Cr. 1-6. Repeatable. F.S. Graduate research projects performed under the supervision of selected faculty members in the molecular, cellular, and developmental biology program.

MCDB 698. Seminar in Molecular, Cellular, and Developmental Biology. (Cross-listed with BBMB, GDCB, Micro, V MPM). (2-0) Cr. 1-2. Repeatable. F.S. Student and faculty presentations.

MCDB 699. Research. Cr. arr. Repeatable.