Iowa State University

Iowa State University

2007-2009 Courses and Programs

Iowa State University Catalog

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Biomedical Sciences (B M S)

300 |400 |Graduate Courses |

Richard J. Martin, Chair of Department
Distinguished Professors: Anderson
Distinguished Professors (Emeritus): Christensen, Dellmann
University Professors: Draper
University Professors (Emeritus): Adams, Reece
Professors: Bloedel, Evans, Ghoshal, Hsu, Anumantha Kanthasamy, King, Lin, R. Martin, Randic, Riedesel, Sharp, Uemura, Ware
Professors (Emeritus): Ahrens, Bal, Carithers, Dyer, Engen, Hembrough, Pineda, Vanmeter
Professors (Collaborators): Horst
Associate Professors: Bracha, Day, Franke, Jeftinija, J. Ourednik, W. Ourednik, Sakaguchi
Professors (Emeritus): Crump, P. Martin
Associate Professors (Collaborators): Goff, Hamouche, Kangas
Assistant Professors: Greenlee, Arthi Kanthasamy, Kimber, Rowe
Assistant Professors (Adjunct): Barnhill
Assistant Professors (Collaborators): Barton, Kesl, Kwon
Senior Lecturers: Bolser
Lecturers: Kibbel

Professional Program of Study

For professional curriculum in veterinary medicine leading to the degree doctor of veterinary medicine, see Veterinary Medicine, Curriculum.

A good foundation in anatomy, physiology, and pharmacology of animals is necessary to understand the mechanisms of animal disease processes and their treatment. Study of mammalian anatomy and physiology prepares students with a background in the structural and functional activities of cells, tissues, organs, and body systems of importance to veterinary medicine.

An understanding of drug action is essential for rational drug therapy. The general pharmacology courses provide students with a background in basic pharmacology to include pharmacodynamics, toxicology, and the clinical application of drugs. Special emphasis is placed on chemical agents and therapeutic practices specific to veterinary medicine.

Graduate Programs

The department offers work for the degrees master of science and doctor of philosophy with a major in biomedical sciences and specializations in anatomy, physiology, pharmacology, and cell biology. Up to 10 credits of dual-listed veterinary anatomy courses may be applied for major graduate credit. Departmental research facilities provide for training in experimental anatomy, pharmacology, and physiology. Graduate studies are supervised by faculty members recognized in their areas of expertise. Current areas of research include: diabetes mellitus, glia-neuron signaling, neurophysiology of pain, neurotoxicology, physiology and pharmacology of nematode ion-channels, Parkinson's disease, Alzheimer's disease, pharmacology of schistosomiasis, physiology and pharmacology of thalamic neurons, physiology of the retina, and study of neural stem cells. The objective of the department is to prepare graduate students for successful careers in biomedical research and professional service. The department is part of interdepartmental programs in neuroscience, toxicology, and molecular, cellular, and developmental biology. The combined Ph.D./DVM program is an option.

Foreign language requirements may be established by the student's program of study committee.

Courses open for nonmajor graduate credit: 354, 421.

Courses primarily for professional curriculum students

B M S 329. Anatomy and Physiology of Domestic Animals. (3-0) Cr. 3. S. Prereq: Biol 212, 212L. Survey of body systems of domestic animals. Provides a medical science orientation particularly useful to students in a preveterinary medicine curriculum.

B M S 330. Principles of Morphology I. (Dual-listed with 530). (3-6) Cr. 5. F. Prereq: First-year classification in veterinary medicine. Anatomy of the dog.

B M S 331. Principles of Morphology II. (Dual-listed with 531). (2-6) Cr. 4. S. Prereq: First-year classification in veterinary medicine. Comparative and topographic anatomy of horse, ruminants, pig, and chicken.

B M S 333. Biomedical Sciences I. (5-3) Cr. 6. F. Prereq: First-year classification in veterinary medicine. Microscopic anatomy and physiology of cells, tissues, cardiovascular system, respiratory system, and urinary system.

B M S 334. Biomedical Sciences II. (5-3) Cr. 6. S. Prereq: First-year classification in veterinary medicine. Microscopic anatomy of the immune system and integument. Microscopic anatomy and physiology of the digestive system, endocrine system, and reproductive system.

B M S 337. Neuroanatomy. (Dual-listed with 537). (2-2) Cr. 3. S. Prereq: First-year classification in veterinary medicine. Neuroanatomy of domestic animals.

B M S 339. Clinical Foundations I. (Cross-listed with V C S). (0-2) Cr. 1. F. Prereq: First-year classification in veterinary medicine. Canine physical examination; basic behavior, animal handling and restraint; medical record keeping.

B M S 345. Case Study I. (0-2) Cr. 1. F. Prereq: First-year classification in veterinary medicine. Clinical applications of basic sciences taught concurrently in the fall semester of the first year curriculum in veterinary medicine.

B M S 346. Case Study II. (0-1) Cr. 1. S. Prereq: First-year classification in veterinary medicine. Clinical applications of basic sciences taught concurrently in the spring semester of the first year curriculum in veterinary medicine.

B M S 354. General Pharmacology. (Dual-listed with 554). (3-0) Cr. 3. S. Prereq: 333, 334. General principles; drug disposition; drugs acting on the nervous, cardiovascular, renal, gastrointestinal, and endocrine systems. Nonmajor graduate credit.

B M S 403. Behavior of Domestic Animals. (1-0) Cr. 1. Alt. S., offered 2008. Prereq: Classification in veterinary medicine. Normal and abnormal behavior of domestic animals.

B M S 415. Anatomy of Laboratory Animals. (Dual-listed with 515). (1-2) Cr. 2. Alt. S., offered 2008. Prereq: One year of college biology. Gross and microscopic anatomy of laboratory animals.

B M S 416. Avian Anatomy. (Dual-listed with 516). (1-2) Cr. 2. Alt. S., offered 2009. Prereq: One year college biology. Gross and microscopic anatomy of domestic, exotic, and pet birds.

B M S 421. Special and Applied Anatomy of the Horse. (1-3) Cr. 2. F. Prereq: 330 or 331 or An S 316 or 415, classification in veterinary medicine. Special and applied anatomy of the horse. Nonmajor graduate credit.

B M S 443. Pharmacology and Therapeutics. (Dual-listed with 543). (3-0) Cr. 3. F. Prereq: 354. Pharmacology and therapeutic uses of fluids, antimicrobial and antiparasitic drugs, clinical use of veterinary drugs, and adverse drug reactions.

B M S 490. Independent Study. Cr. 1-5. Repeatable. Prereq: Permission of instructor.
H. Honors

B M S 496. International Preceptorship. (0-40) Cr. 1-12. Repeatable. F.S.SS. Prereq: Second-year classification in veterinary medicine. International Preceptorships and Study Abroad Group programs. This course will provide opportunities for students to be involved in applied clinical, production, and/or research experiences in international locations. The course consists of 40 hour per week experiential learning opportunites.

Courses primarily for graduate students, open to qualified undergraduate students

B M S 501. Selected Research Methods in Biomedical Sciences. (0-8) Cr. 3. F.S.SS. Prereq: Graduate classification, permission of a BMS faculty member. Experience in biomedical techniques in selected BMS laboratories that include but is not limited to cytochemical methods, molecular biological techniques, extracellular and intracellular unit recording, microiontophoresis, microinjection, spectrophoto-fluorometric analysis of chemicals, use of radioisotopes, radioimmunoassay, Ca2+ imaging, confocal microscopy, fluorescence microscopy, and immunocytochemistry.

B M S 515. Anatomy of Laboratory Animals. (Dual-listed with 415). (1-2) Cr. 2. Alt. S., offered 2008. Prereq: One year of college biology. Gross and microscopic anatomy of laboratory animals.

B M S 516. Avian Anatomy. (Dual-listed with 416). (1-2) Cr. 2. Alt. S., offered 2009. Prereq: One year college biology. Gross and microscopic anatomy of domestic, exotic, and pet birds.

B M S 530. Principles of Morphology I. (Dual-listed with 330). (3-6) Cr. 5. F. Prereq: 10 credits in biological science and permission of the instructor. Anatomy of the dog.

B M S 531. Principles of Morphology II. (Dual-listed with 331). (2-6) Cr. 4. S. Prereq: B M S 530. Comparative and topographic anatomy of horse, ruminants, pig, and chicken.

B M S 537. Neuroanatomy. (Dual-listed with 337). (2-2) Cr. 3. S. Prereq: 10 credits in biological science and permission of the instructor. Neuroanatomy of domestic animals.

B M S 542. Introduction to Molecular Biology Techniques. (Cross-listed with GDCB, BBMB, BCB, FS HN, Hort, NutrS, VDPAM, EEOB,). Cr. 1. Repeatable. F.S.SS. Prereq: Graduate classification. Workshops in basic molecular biology techniques and related procedures. Satisfactory-fail only.
A. DNA Techniques. Includes genetic engineering procedures, sequencing, PCR, and genotyping. (F.S.SS.)
B. Protein Techniques. Includes fermentation, protein isolation, protein purification, SDS-PAGE, Western blotting, NMR, confocal microscopy and laser microdissection, immunophenotyping, and monoclonol antibody production. (S.SS.)
C. Cell Techniques. Includes immunophenotyping, ELISA, flow cytometry, microscopic techniques, and image analysis. (F.S.)
D. Plant Transformation. Includes Agrobacterium and particle gun-mediated transformation of tobacco, Arabidopsis, and maize, and analysis of transformants. (S.)
E. Proteomics. Includes two-dimensional electrophoresis, laser scanning, mass spectrometry, and database searching. (F.)

B M S 543. Pharmacology and Therapeutics. (Dual-listed with 443). (3-0) Cr. 3. F. Prereq: 554. Pharmacology and therapeutic uses of fluids, antimicrobial and antiparasitic drugs, clinical use of veterinary drugs, and adverse drug reactions.

B M S 549. Advanced Vertebrate Physiology I. (Cross-listed with An S, HHP). (3-0) Cr. 3. F. Prereq: Biol 335, credit or enrollment in BBMB 404 or 420. Neurophysiology, sensory systems, muscle, neuroendocrinology, and endocrinology.

B M S 552. Advanced Vertebrate Physiology II. (Cross-listed with An S, HHP). (3-0) Cr. 3. S. Prereq: Biol 335; credit or enrollment in BBMB 404 or 420. Cardiovascular, renal, respiratory, and digestive physiology.

B M S 554. General Pharmacology. (Dual-listed with 354). (Cross-listed with Tox). (3-0) Cr. 3. S. Prereq: 549 and 552; BBMB 404, 405. General principles; drug disposition; drugs acting on the nervous, cardiovascular, renal, gastrointestinal, and endocrine systems.

B M S 556. Cellular, Molecular and Developmental Neuroscience. (Cross-listed with GDCB, Neuro). Cr. 3-4. F. Prereq: Biol 335 or Biol 436; physics recommended. Fundamental principles of neuroscience including cellular and molecular neuroscience, nervous system development, sensory, motor and regulatory systems.

B M S 575. Cell Biology. (Cross-listed with Tox). (3-0) Cr. 3. F. Prereq: 10 credits in biological science and permission of instructor. A multi-instructor course covering major topics in cell structure and function, including: universal features of prokaryotic and eukaryotic cells, types of utilization and conversion of energy, genetic control of cell shape and functionality, internal organization of cells, communication between cells and their environment, development of multicellular systems. Students have to write a term paper.

B M S 590. Special Topics. Cr. 1-7. Repeatable. Prereq: Permission of instructor.
A. Anatomy
B. Physiology
C. Pharmacology
D. Cell biology

B M S 599. Creative Component. Cr. 1-3. Prereq: Enrollment in BMS graduate program. Permission of instructor. Creative component for non-thesis master of science degree.

Courses for graduate students

B M S 688. Research Review. Cr. 1. Repeatable. F.S. A forum for B M S students to gain experience in the critical exchange of ideas through oral presentation and discussion of scientific information.

B M S 690. Advanced Topics. Cr. 1-5. Repeatable.Prereq : Permission of instructor.
A. Anatomy
B. Physiology
C. Pharmacology
D. Cell biology

B M S 698. Seminar. Cr. 1. Repeatable.
A. Cr. R each time taken. F.S. Attendance required.
B. Cr. 1 each time taken. F.S.SS. Attendance and presentation required. Offered on a satisfactory-fail grading basis only.

B M S 699. Research. Cr. arr. Repeatable.
A. Anatomy
B. Physiology
C. Pharmacology
D. Cell biology