200 | 300 | 400 | Graduate Courses Genetics (Gen) Courses Primarily for Undergraduate Students Gen 110. Genetics Orientation. (1-0) Cr. 0.5. F. First 8 weeks. Orientation to the area of genetics. For students considering a major in genetics. Specializations and career opportunities. Offered on a satisfactory-fail grading basis only. Gen 260. Human Heredity and Society. (3-0) Cr. 3. F. Prereq: One semester of college biology or Anthr 202. A survey course in genetics for non-biology majors interested in heredity and its importance, and implications to self and society. Not recommended for those intending to take advanced courses in genetics. Credit for graduation will not be allowed for more than one of the following: 260, 301, 320, Biol 301 and 301L and Agron 320. Gen 298. Cooperative Education. Cr. R. F.S.SS. Prereq: Permission of department cooperative education coordinator; sophomore classification. Required of all cooperative education students. Students must register for this course prior to commencing each work period. Gen 301. Principles of Genetics. (Same as Biol 301.) See Biology. Credit for graduation will not be allowed for more than one of the following: 260, 301 and 301L, 320, Biol 301 and 301L and Agron 320. Gen 301L. Principles of Genetics Laboratory. (Same as Biol 301L.) See Biology. Gen 308. Biotechnology in Agriculture, Food, and Human Health. (Dual-listed with 508.) (3-0) Cr. 3. F. S.SS. Prereq: Biol 201 and 202. Scientific principles and techniques in biotechnology. Products and applications in agriculture, food, and human health. Ethical, legal, and social implications of biotechnology. A research paper is required for graduate credit. Gen 320. Genetics, Agriculture and Biotechnology. (Same as Agron 320.) (3-0) Cr. 3. F.S. Prereq: Biol 202. Transmission genetics with an emphasis on applications in agriculture, the structure and expression of the gene, how genes behave in populations and how recombinant DNA technology can be used to improve agriculture. Credit for graduation will not be allowed for more than one of the following: 260, 301, 320, Biol 301 and 301L and Agron 320. Gen 340. Human Genetics. (3-0) Cr. 3. Alt. S., offered 2004. Prereq: Biol 301 or Gen 301. Fundamental concepts and current issues of human genetics. Human chromosome analysis, pedigree analysis, gene mapping, the human genome project, sex determination, genetics of the immune system, genetics of cancer, gene therapy, the genetic basis of human diversity, eugenics. Gen 398. Cooperative Education. Cr. R. F.S.SS. Prereq: Permission of department cooperative education coordinator; junior classification. Required of all cooperative education students. Students must register for this course prior to commencing each work period. Gen 410. Transmission Genetics. (3-0) Cr. 3. F. Prereq: Biol 301 or Gen 301. The principles and practice of transmission genetics. The Mendelian concept of the gene, mutational analysis of gene function, linkage and gene mapping, genetic fine structure analysis, chromosomal aberrations, aneuploidy and polyploidy, extrachromosomal inheritance, analysis of genetic pathways, genetics of quantitative traits. Nonmajor graduate credit. Gen 411. Molecular Genetics. (3-0) Cr. 3. S. Prereq: Biol 302. The principles of molecular genetics: gene structure and function at the molecular level, including regulation of gene expression, genetic rearrangement, and the organization of genetic information in prokaryotes and eukaryotes. Nonmajor graduate credit. Gen 462. Evolutionary Genetics. (Dual-listed with 562; same as Zool 462.) (3-0) Cr. 3. S. Prereq: Biol 303. The genetic basis of evolutionary processes in higher organisms. The role of genetic variation in adaptation, natural selection, adaptive processes, and the influence of random processes on evolutionary change. Nonmajor graduate credit Gen 490. Independent Study. Cr. arr. Prereq: 301, junior or senior classification, permission of instructor. Students in the College of Agriculture may use no more than 6 credits of Gen 490 toward the total of 128 credits required for graduation; students in the College of Liberal Arts and Sciences may use no more than 9 credits of Gen 490 toward graduation. R. Genetics research. Cr. 1 to 5 each time taken. S. Attendance and critique of genetics seminars. Cr. 1. Offered on a satisfactory-fail grading basis only. U. Laboratory teaching experience. For students registering to be undergraduate laboratory assis tants. Cr. 1 to 2. Offered on a satisfactory-fail grading basis only. Gen 491. Undergraduate Seminar. (1-0) Cr. 1. F. Prereq: Junior classification. The investigation of current issues in genetics. Graduate school and employment opportunities discussed. Practice in résumé writing and interview techniques. Required for majors in genetics. Gen 495. Molecular Biology for Computational Scientists. (Same as BCB 495.) (3-0) Cr. 3. F. Dobbs. Survey of molecular cell biology and molecular genetics for non-biologists, especially those interested in bioinformatics/computational biology. Basic cell structure and function; principles of molecular genetics; biosynthesis, structure, and function of DNA, RNA, and proteins; regulation of gene expression; selected topics. Provides biological background for BCB/Gen/Com S/Math 594. Credit for graduation will not be allowed for more than one of the following: Gen 411 and 495. Nonmajor graduate credit. Gen 498. Cooperative Education. Cr. R. F.S.SS. Prereq: Permission of department cooperative education coordinator; senior classification. Required of all cooperative education students. Students must register for this course prior to commencing each work period. Courses Primarily for Graduate Students, Open to Qualified Undergraduate Students Gen 508. Biotechnology in Agriculture, Food , and Human Health. (Dual-listed in 308.) (3-0) Cr. 3. F.S. Prereq; Biol 201 and 202. Scientific principles and techniques in biotechnology. Products and applications in agriculture, food, and human health. Ethical, legal, and social implications of biotechnology. A research paper is required for graduate credit. Gen 510. Transmission Genetics. (3-0) Cr. 3. Prereq: 410 or graduate standing. An in-depth investigation of the modern research practices of transmission genetics. Designed for students interested in genetic research. Topics include: Mendelian genetic analysis, analysis of genetic pathways, mutational analysis of gene function, chromosomal mechanics, gene mapping, extranuclear inheritance, human genetic analysis, characteristics of popular genetic model organisms. Gen 511. Molecular Genetics. (Same as MCDB 511.) (3-0) Cr. 3. S. Prereq: Biol 301 and BBMB 405. The principles of molecular genetics: gene structure and function at the molecular level, including regulation of gene expression, genetic rearrangement, and the organization of genetic information in prokaryotes and eukaryotes. Gen 512. Plant Growth and Development. (Same as Bot 512.) See Botany. Gen 520. Genetic Engineering. (Same as BBMB 520, MCDB 520.) (3-0) Cr. 3. Alt. F., offered 2003. Prereq: 411 or BBMB 405. Strategies and methods of gene cloning, restriction endonuclease mapping, southern hybridization, isolation and manipulation of plasmid DNA, and detection of specific genes in bacteria. Gen 536. Genetic Statistics. (Same as Stat 536.) See Statistics. Gen 537. Genetic Statistics. (Same as Stat 537.) See Statistics. Gen 548. Fundamental Algorithms in Computational Biology. (Same as BCB 548.) See Bioinformatics and Computational Biology. Gen 550. Evolutionary Problems for Computational Biologists. (Same as BCB 550.) See Bioinformatics and Computational Biology. Gen 556. Computational Genomics and Evolution. (Same as BCB 556.) (3-0) Cr. 3. Alt. S., offered 2005. Prereq: Biol 301. Gu. Introduction to evolutionary sequence analysis at the genome level. Topics include sequence alignment, phylogenetic inference, molecular clock analysis, ancestral state inference, sequence/structure relation, functional divergence and prediction, evolutionary development, genome duplication, and comparative genomics. Focus will be on data analysis and biological interpretation. Gen 557. Statistical Methods for Computational Biology. (Same as BCB 557.) (2-0) Cr. 2. Alt. S., offered 2004. Prereq: BCB 594. Gu. Advanced discussion about statistical modeling of DNA and amino acid sequences, microarray expression profiles and other genome-wide data interpretation. Gen 562. Evolutionary Genetics. (Dual-listed with 462; same as Bot 562, Zool 562.) (3-0) Cr. 3. S. Prereq: Biol 303. Graduate study in conjunction with 462. The genetic basis of evolutionary processes in higher organisms. The role of genetic variation in adaptation, natural selection, adaptive processes, and the influence of random processes on evolutionary change. Gen 563. Molecular Phylogenetics. (Same as Zool 563.) See Zoology. Gen 565. Professional Practice in the Life Sciences. (Same as Pl P 565.) See Plant Pathology. Gen 566. Molecular Evolution. (Same as Bot 566.) See Botany. Gen 590. Special Topics. Cr. 1 to 3. Prereq: 301 or 320. Gen 594. Computational Molecular Biology. (Same as BCB 594, Com S 594, Math 594.) (3-0) Cr. 3. F.S. Prereq: BCB 484, BCB 495, Stat 432 or equivalent courses and programming experience (C, C++, or Perl). State-of-the-art introduction to bioinformatics with emphasis on concepts and principles, combined with hands-on (keyboard) applications. Topics typically include: molecular databases, score-based sequence analysis, amino acid substitution scoring matrices, query search problems, dynamic programming and other methods for pairwise sequence alignment, motif identification, multiple sequence alignment, construction of phylogenetic trees from sequenceing data; gene structure prediction, protein structure prediction. Gen 596. Genomic Data Processing. (Same as BCB 596, Com S 596.) (3-0) Cr. 3. F. Prereq: Some knowledge of programming. Chou. Practical aspects of genomic data processing. Emphasis on projects that carry out major steps in data processing using important bioinformatics tools. Topics include base-calling, raw sequence cleaning and contaminant removal; shotgun assembly procedures and EST clustering methods; genome closure strategies and practices; sequence homology search and function prediction; annotation and submission of GenBank reports; and data collection and dissipation through the Internet. Courses for Graduate Students Gen 615. Molecular Immunology. (Same as BBMB 615.) See Biochemistry, Biophysics and Molecular Biology. Gen 675. Nucleic Acid Structure and Function. (Same as BBMB 675.) See Biochemistry, Biophysics and Molecular Biology. Gen 696. Seminar in Plant Physiology and Molecular Biology. (Same as Bot 696.) See Botany. Gen 698. Seminar in Molecular, Cellular, and Developmental Biology. (Same as MCDB 698.) See Molecular, Cellular, and Developmental Biology. Gen 699. Research.