David J. Oliver
Ph.D. Cornell University, 1975
Much of the research in my laboratory is directed to understanding
how plants alter metabolic function during growth, specifically how
plant mitochondria change. The largest change occurs in leaf
mitochondria where they switch from being classical respiratory
organelle to an organelle that is primarily directed to
photosynthesis, the photorespiratory conversion of glycine to serine.
We have been investigating the enzymology of the enzyme that
catalyzes this reaction, glycine decarboxylase, as well as how its
expression is limited to leaves grown in the light. Another major
metabolic change that we have investigated is during seed germination
where the mitochondria begin by being involved in lipid conversion to
carbohydrate and soon become the major site of respiration. Our
studies on heavy metals in plants strive to isolate the genes
responsible for resistance to the normal levels of metals found soils
and to augment their expression by genetic engineering methods to
make plants that are highly metal-resistant. These plants would be
used to revegetate metal contaminated soils and might be used to
remove metals from these sites. Finally we are studying how plants
can be altered to change the products they make and their fitness for
- Xiang, C. and D.J. Oliver. 1998. Glutathione metabolic Genes
Coordinately Respond to Heavy Metals and Jasmonic Acid in
Arabidopsis. The Plant Cell 10:1539-1550.
- Falk, K.L., R.H. Behal, C. Xiang, and D.J. Oliver. 1998.
Metabolic Bypass of the TCA Cycle During Lipid Mobilization in
Germinating Oilseeds: Regulation of NAD+-Dependent
Isocitrate Dehydrogenase Versus Fumarase. Plant Physiology
- Xiang, C. and D.J. Oliver 1998. Glutathione and its Central
Role in Mitigating Plant Stress. Handbook of Plant Stress (M.
Pessarakli, ed.) Marcel Dekker, Inc., New York, (in press).
- Pesic, B., R. Raman, C.L. Lasko, and D.J. Oliver. 1998.
Natural Polymers for Removal of Heavy Metals from Water: Sorption
of Copper by Chitosan-Pyridoxal-Epichlorohydrin. Journal of
Mining and Metallurgy 34:91-110.
- Oliver, D.J., R.H. Behal, C. Xiang, and K.L. Falk. 1998.
Changes in Fumarase and NAD+-Dependent Isocitrate
Dehydrogenase During Arabidopsis Seed Germination. Plant
Mitochondria (E. Glaser, P. Gardestrom, D. Glimelius, and I.M.
Moller, eds.) Backhys Publishers, Warmonderweg, pp. 395-400.
- Abbaraju, H.R. and D.J. Oliver. 1999. Identification of an
Unusual Myb-type Transcription Factor that Controls the
Light-Dependent Expression of the H-Protein of Glycine
Decarboxylase. Plant Molecular Biology (submitted).
- Xiang, C., P. Han, and D.J. Oliver. 1999. In solium
Selection for Arabidopsis Transformants Resistant to Kanamycin.
Plant Molecular Biology 17:59-65.
- Wurtele, E.S., R.H. Behal, X. Cui, J. Ke, J.L. Johnson, F.
Lui, B.J. Nikolau, D.H. Oliver, and P.B. Schnable. 1999. Molecular
Biology of Acetyl-CoA Generation. (Sanchex, J. Cerda-Imedo, E.,
Martinex-Forece, E., eds). University of Sevilla Press. pp.
- Xiang, C., P. Han, I Lutziger, K. Wang, and D.J. Oliver. 1999.
A Mini Binary Vector Series for Plant Transformation. Plant
Molecular Biology 40:711-717.
- Xiang, C., D. Bertrand, and D.J. Oliver. 1999. Glutathione
Synthesis in Arabidopsis: Multilevel Controls Coordinate
Responses to Stress. Sulfur Metabolism in Plants (in
- Behal, R.H. and D.J. Oliver. 1999. A Second Gene Encoding the
Plastidic Pyruvate Dehydrogenase - Subunit in Arabidopsis
thaliana. Plant Physiology 121:312-313.
- Ke, J. R.H. Behal, S. Yunkers, B.J. Nikolau, E.S. Wurtele, and
D.J. Oliver. 2000. The role of Pyruvate Dehydrogenase and
Acetyl-CoA Synthetase in Fatty Acid Synthesis in Developing
Arabidopsis Seeds. Plant Physiology 123:497-508.