Week of Sept. 22

Viral Pathogenesis

Pl P 692

Assignments

Monday

• Lucas. 2006. Plant viral movement proteins: Agents for cell-to-cell trafficking of viral genomes. Virology. 344:169-184
• Nagy and Pogany. 2006. Yeast as a model host to dissect functions of viral and host factors in tombusvirus replication. Virology. 344:211-220

Wednesday
(review articles)

• Ding and Voinnet. 2007. Antiviral Immunity Directed by Small RNAs. Cell. 130:413-426
• Robaglia and Caranta. 2006.Translation initiation factors: a weak link in plant RNA virus infection. Trends Plant Sci. 11:40-45

(paper for discussion)

• F. Qu, X. Ye, and T. J. Morris. 2008. Arabidopsis DRB4, AGO1, AGO7, and RDR6 participate in a DCL4-initiated antiviral RNA silencing pathway negatively regulated by DCL1. Proc. Natl. Acad. Sci. USA. [Epub ahead of print]. Brian

Friday (paper for discussion)

• Charron C, NicolaÔ M, Gallois JL, Robaglia C, Moury B, Palloix A, Caranta C. 2008. Natural variation and functional analyses provide evidence for co-evolution between plant eIF4E and potyviral VPg. Plant J. 54(1):56-68. Peter

… N. Baumberger, C. H. Tsai, M. Lie, E. Havecker, D. C. Baulcombe. 2007. The Polerovirus silencing suppressor P0 targets ARGONAUTE proteins for degradation. Curr. Biol. 17: 1609-14. Charles

Lecture slides and references

Viral_Path.ppt

Additional review articles

• Whitham and Wang. 2004. Roles for host factors in plant viral pathogenicity. Curr. Op. Plant Biol. 7:365-371
• Ahlquist et al. 2003. Host factors in positive-strand RNA virus genome replication. J. Virol. 77:8181-8186
• Carrington et al. 1996. Cell-to-cell and long-distance transport of viruses in plants. Plant Cell. 8:1669-1681